Mount Sinai Global Health and Emerging Pathogens Institute

Search results

  • 2021

    Reduced Nucleoprotein Availability Impairs Negative-Sense RNA Virus Replication and Promotes Host Recognition

    Nilsson-Payant, B. E., Blanco-Melo, D., Uhl, S., Escudero-Pérez, B., Olschewski, S., Thibault, P., Panis, M., Rosenthal, M., Muñoz-Fontela, C., Lee, B. & tenOever, B. R., May 2021, In: Journal of Virology. 95, 9, e02274-20.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • Repeated cross-sectional sero-monitoring of SARS-CoV-2 in New York City

    Stadlbauer, D., Tan, J., Jiang, K., Hernandez, M. M., Fabre, S., Amanat, F., Teo, C., Arunkumar, G. A., McMahon, M., Capuano, C., Twyman, K., Jhang, J., Nowak, M. D., Simon, V., Sordillo, E. M., van Bakel, H. & Krammer, F., 4 Feb 2021, In: Nature. 590, 7844, p. 146-150 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    90 Scopus citations
  • Replication-competent ∆ns1 influenza a viruses expressing reporter genes

    Nogales, A., Schotsaert, M., Rathnasinghe, R., Dediego, M. L., García-Sastre, A. & Martinez-Sobrido, L., Apr 2021, In: Viruses. 13, 4, 698.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Restriction factor compendium for influenza A virus reveals a mechanism for evasion of autophagy

    Martin-Sancho, L., Tripathi, S., Rodriguez-Frandsen, A., Pache, L., Sanchez-Aparicio, M., McGregor, M. J., Haas, K. M., Swaney, D. L., Nguyen, T. T., Mamede, J. I., Churas, C., Pratt, D., Rosenthal, S. B., Riva, L., Nguyen, C., Beltran-Raygoza, N., Soonthornvacharin, S., Wang, G., Jimenez-Morales, D., De Jesus, P. D., & 10 othersMoulton, H. M., Stein, D. A., Chang, M. W., Benner, C., Ideker, T., Albrecht, R. A., Hultquist, J. F., Krogan, N. J., García-Sastre, A. & Chanda, S. K., Oct 2021, In: Nature Microbiology. 6, 10, p. 1319-1333 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • Safety and Immunogenicity Analysis of a Newcastle Disease Virus (NDV-HXP-S) Expressing the Spike Protein of SARS-CoV-2 in Sprague Dawley Rats

    Tcheou, J., Raskin, A., Singh, G., Kawabata, H., Bielak, D., Sun, W., González-Domínguez, I., Sather, D. N., García-Sastre, A., Palese, P., Krammer, F. & Carreño, J. M., 18 Nov 2021, In: Frontiers in Immunology. 12, 791764.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Safety and Immunogenicity of a Newcastle Disease Virus Vector-Based SARS-CoV-2 Vaccine Candidate, AVX/COVID-12-HEXAPRO (Patria), in Pigs

    Lara-Puente, J. H., Carreño, J. M., Sun, W., Suárez-Martínez, A., Ramírez-Martínez, L., Quezada-Monroy, F., de la Rosa, G. P., Vigueras-Moreno, R., Singh, G., Rojas-Martínez, O., Chagoya-Cortés, H. E., Sarfati-Mizrahi, D., Soto-Priante, E., López-Macías, C., Krammer, F., Castro-Peralta, F., Palese, P., García-Sastre, A. & Lozano-Dubernard, B., 1 Oct 2021, In: mBio. 12, 5, e01908-21.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • SARS-CoV-2 infection induces beta cell transdifferentiation

    Tang, X., Uhl, S., Zhang, T., Xue, D., Li, B., Vandana, J. J., Acklin, J. A., Bonnycastle, L. L., Narisu, N., Erdos, M. R., Bram, Y., Chandar, V., Chong, A. C. N., Lacko, L. A., Min, Z., Lim, J. K., Borczuk, A. C., Xiang, J., Naji, A., Collins, F. S., & 5 othersEvans, T., Liu, C., tenOever, B. R., Schwartz, R. E. & Chen, S., 3 Aug 2021, In: Cell Metabolism. 33, 8, p. 1577-1591.e7

    Research output: Contribution to journalArticlepeer-review

    Open Access
    122 Scopus citations
  • SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium

    Eriksen, A. Z., Møller, R., Makovoz, B., Uhl, S. A., tenOever, B. R. & Blenkinsop, T. A., 1 Jul 2021, In: Cell Stem Cell. 28, 7, p. 1205-1220.e7

    Research output: Contribution to journalArticlepeer-review

    Open Access
    46 Scopus citations
  • SARS-CoV-2 in Transit: Characterization of SARS-CoV-2 Genomes From Venezuelan Migrants in Colombia

    Patiño, L. H., Ballesteros, N., Muñoz, M., Castañeda, S., Hernández, C., Gomez, S., Florez, C., Rico, A., Pardo, L., Hernandez-Pereira, C. E., Delgado-Noguera, L., Grillet, M. E., Hernandez, M. M., Khan, Z., van de Guchte, A., Dutta, J., Gonzalez-Reiche, A. S., Simon, V., van Bakel, H., Sordillo, E. M., & 2 othersRamírez, J. D. & Paniz-Mondolfi, A. E., Sep 2021, In: International Journal of Infectious Diseases. 110, p. 410-416 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2

    The Personalized Virology Initiative, 22 Jul 2021, In: Cell. 184, 15, p. 3936-3948.e10

    Research output: Contribution to journalArticlepeer-review

    Open Access
    168 Scopus citations
  • SARS-CoV-2 spike E484K mutation reduces antibody neutralisation

    Personalized Virology Initiative study group, Jul 2021, In: The Lancet Microbe. 2, 7, p. e283-e284

    Research output: Contribution to journalLetterpeer-review

    Open Access
    255 Scopus citations
  • SARS-CoV-2 vaccines for all but a single dose for COVID-19 survivors

    Frieman, M., Harris, A. D., Herati, R. S., Krammer, F., Mantovani, A., Rescigno, M., Sajadi, M. M. & Simon, V., Jun 2021, In: eBioMedicine. 68, 103401.

    Research output: Contribution to journalComment/debate

    Open Access
    45 Scopus citations
  • Scalable, effective, and rapid decontamination of SARS-CoV-2 contaminated N95 respirators using germicidal ultraviolet C (UVC) irradiation device

    Rathnasinghe, R., Karlicek, R. F., Schotsaert, M., Koffas, M., Arduini, B. L., Jangra, S., Wang, B., Davis, J. L., Alnaggar, M., Costa, A., Vincent, R., García-Sastre, A., Vashishth, D. & Balchandani, P., Dec 2021, In: Scientific Reports. 11, 1, 19970.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine**

    Jangra, S., De Vrieze, J., Choi, A., Rathnasinghe, R., Laghlali, G., Uvyn, A., Van Herck, S., Nuhn, L., Deswarte, K., Zhong, Z., Sanders, N. N., Lienenklaus, S., David, S. A., Strohmeier, S., Amanat, F., Krammer, F., Hammad, H., Lambrecht, B. N., Coughlan, L., García-Sastre, A., & 2 othersDe Geest, B. G. & Schotsaert, M., 19 Apr 2021, In: Angewandte Chemie - International Edition. 60, 17, p. 9467-9473 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    40 Scopus citations
  • TAP dysfunction in dendritic cells enables noncanonical cross-presentation for T cell priming

    Barbet, G., Nair-Gupta, P., Schotsaert, M., Yeung, S. T., Moretti, J., Seyffer, F., Metreveli, G., Gardner, T., Choi, A., Tortorella, D., Tampé, R., Khanna, K. M., García-Sastre, A. & Blander, J. M., Apr 2021, In: Nature Immunology. 22, 4, p. 497-509 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    27 Scopus citations
  • The arrival and spread of SARS-CoV-2 in Colombia

    Ramírez, J. D., Florez, C., Muñoz, M., Hernández, C., Castillo, A., Gomez, S., Rico, A., Pardo, L., Barros, E. C., Castañeda, S., Ballesteros, N., Martínez, D., Vega, L., Jaimes, J. E., Cruz-Saavedra, L., Herrera, G., Patiño, L. H., Teherán, A. A., Gonzalez-Reiche, A. S., Hernandez, M. M., & 4 othersSordillo, E. M., Simon, V., van Bakel, H. & Paniz-Mondolfi, A., Feb 2021, In: Journal of Medical Virology. 93, 2, p. 1158-1163 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • The Experts Speak: A New Feature in the JICR

    Gale, M., Savan, R., Garcia-Sastre, A., Prokunina-Olsso, L., Balamurugan, K. & Young, H. A., May 2021, In: Journal of Interferon and Cytokine Research. 41, 5, p. 161-163 3 p.

    Research output: Contribution to journalComment/debate

    Open Access
  • The nf-κ b transcriptional footprint is essential for sars-cov-2 replication

    Nilsson-Payant, B. E., Uhl, S., Grimont, A., Doane, A. S., Cohen, P., Patel, R. S., Higgins, C. A., Acklin, J. A., Bram, Y., Chandar, V., Blanco-Melo, D., Panis, M., Lim, J. K., Elemento, O., Schwartz, R. E., Rosenberg, B. R., Chandwani, R. & tenOever, B. R., Dec 2021, In: Journal of Virology. 95, 23, e01257-21.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    55 Scopus citations
  • The spike d614g mutation increases sars-cov-2 infection of multiple human cell types

    Daniloski, Z., Jordan, T. X., Ilmain, J. K., Guo, X., Bhabha, G., Tenoever, B. R. & Sanjana, N. E., Feb 2021, In: eLife. 10, p. 1-16 16 p., e65365.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    124 Scopus citations
  • The virucidal effects of 405 nm visible light on SARS-CoV-2 and influenza A virus

    Rathnasinghe, R., Jangra, S., Miorin, L., Schotsaert, M., Yahnke, C. & Garcίa-Sastre, A., Dec 2021, In: Scientific Reports. 11, 1, 19470.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    25 Scopus citations
  • TIPICO X: report of the 10th interactive infectious disease workshop on infectious diseases and vaccines

    Rivero-Calle, I., Gómez-Rial, J., Bont, L., Gessner, B. D., Kohn, M., Dagan, R., Payne, D. C., Bruni, L., Pollard, A. J., García-Sastre, A., Faustman, D. L., Osterhaus, A., Butler, R., Giménez Sánchez, F., Álvarez, F., Kaforou, M., Bello, X. & Martinón-Torres, F., 2021, In: Human Vaccines and Immunotherapeutics. 17, 3, p. 759-772 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • TIPICO XI: report of the first series and podcast on infectious diseases and vaccines (aTIPICO)

    Martinón-Torres, F., García-Sastre, A., Pollard, A. J., Martín, C., Osterhaus, A., Ladhani, S. N., Ramilo, O., Gómez Rial, J., Salas, A., Bosch, F. X., Martinón-Torres, M., Mina, M. J. & Cherry, J., 2021, In: Human Vaccines and Immunotherapeutics. 17, 11, p. 4299-4327 29 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Tissue-based SARS-CoV-2 detection in fatal COVID-19 infections: Sustained direct viral-induced damage is not necessary to drive disease progression

    El Jamal, S. M., Pujadas, E., Ramos, I., Bryce, C., Grimes, Z. M., Amanat, F., Tsankova, N. M., Mussa, Z., Olson, S., Salem, F., Miorin, L., Aydillo, T., Schotsaert, M., Albrecht, R. A., Liu, W. C., Marjanovic, N., Francoeur, N., Sebra, R., Sealfon, S. C., García-Sastre, A., & 3 othersFowkes, M., Cordon-Cardo, C. & Westra, W. H., Aug 2021, In: Human Pathology. 114, p. 110-119 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    26 Scopus citations
  • TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation

    Ho, J. S. Y., Mok, B. W. Y., Campisi, L., Jordan, T., Yildiz, S., Parameswaran, S., Wayman, J. A., Gaudreault, N. N., Meekins, D. A., Indran, S. V., Morozov, I., Trujillo, J. D., Fstkchyan, Y. S., Rathnasinghe, R., Zhu, Z., Zheng, S., Zhao, N., White, K., Ray-Jones, H., Malysheva, V., & 33 othersThiecke, M. J., Lau, S. Y., Liu, H., Zhang, A. J., Lee, A. C. Y., Liu, W. C., Jangra, S., Escalera, A., Aydillo, T., Melo, B. S., Guccione, E., Sebra, R., Shum, E., Bakker, J., Kaufman, D. A., Moreira, A. L., Carossino, M., Balasuriya, U. B. R., Byun, M., Albrecht, R. A., Schotsaert, M., Garcia-Sastre, A., Chanda, S. K., Miraldi, E. R., Jeyasekharan, A. D., TenOever, B. R., Spivakov, M., Weirauch, M. T., Heinz, S., Chen, H., Benner, C., Richt, J. A. & Marazzi, I., 13 May 2021, In: Cell. 184, 10, p. 2618-2632.e17

    Research output: Contribution to journalArticlepeer-review

    Open Access
    62 Scopus citations
  • Tox2 is required for the maintenance of GC TFH cells and the generation of memory TFH cells

    Horiuchi, S., Wu, H., Liu, W. C., Schmitt, N., Provot, J., Liu, Y., Bentebibel, S. E., Albrecht, R. A., Schotsaert, M., Forst, C. V., Zhang, B. & Ueno, H., Oct 2021, In: Science advances. 7, 41, abj1249.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • Transcriptomics-based drug repositioning pipeline identifies therapeutic candidates for COVID-19

    Le, B. L., Andreoletti, G., Oskotsky, T., Vallejo-Gracia, A., Rosales, R., Yu, K., Kosti, I., Leon, K. E., Bunis, D. G., Li, C., Kumar, G. R., White, K. M., García-Sastre, A., Ott, M. & Sirota, M., Dec 2021, In: Scientific Reports. 11, 1, 12310.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    27 Scopus citations
  • Unconventional viral gene expression mechanisms as therapeutic targets

    Ho, J. S. Y., Zhu, Z. & Marazzi, I., 20 May 2021, In: Nature. 593, 7859, p. 362-371 10 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    26 Scopus citations
  • Variable cellular responses to SARS-CoV-2 in fully vaccinated patients with multiple myeloma

    PVI/Seronet Study Group, 8 Nov 2021, In: Cancer Cell. 39, 11, p. 1442-1444 3 p.

    Research output: Contribution to journalLetterpeer-review

    Open Access
    60 Scopus citations
  • Virus-induced senescence is a driver and therapeutic target in COVID-19

    Lee, S., Yu, Y., Trimpert, J., Benthani, F., Mairhofer, M., Richter-Pechanska, P., Wyler, E., Belenki, D., Kaltenbrunner, S., Pammer, M., Kausche, L., Firsching, T. C., Dietert, K., Schotsaert, M., Martínez-Romero, C., Singh, G., Kunz, S., Niemeyer, D., Ghanem, R., Salzer, H. J. F., & 28 othersPaar, C., Mülleder, M., Uccellini, M., Michaelis, E. G., Khan, A., Lau, A., Schönlein, M., Habringer, A., Tomasits, J., Adler, J. M., Kimeswenger, S., Gruber, A. D., Hoetzenecker, W., Steinkellner, H., Purfürst, B., Motz, R., Di Pierro, F., Lamprecht, B., Osterrieder, N., Landthaler, M., Drosten, C., García-Sastre, A., Langer, R., Ralser, M., Eils, R., Reimann, M., Fan, D. N. Y. & Schmitt, C. A., 11 Nov 2021, In: Nature. 599, 7884, p. 283-289 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    166 Scopus citations
  • Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses

    Chen, W., Foo, S. S., Hong, E., Wu, C., Lee, W. S., Lee, S. A., Evseenko, D., Moreira, M. E. L., García-Sastre, A., Cheng, G., Nielsen-Saines, K., Brasil, P., Avvad-Portari, E. & Jung, J. U., Apr 2021, In: Nature Microbiology. 6, 4, p. 455-466 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • 2020

    2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

    Kuhn, J. H., Adkins, S., Alioto, D., Alkhovsky, S. V., Amarasinghe, G. K., Anthony, S. J., Avšič-Županc, T., Ayllón, M. A., Bahl, J., Balkema-Buschmann, A., Ballinger, M. J., Bartonička, T., Basler, C., Bavari, S., Beer, M., Bente, D. A., Bergeron, É., Bird, B. H., Blair, C., Blasdell, K. R., & 209 othersBradfute, S. B., Breyta, R., Briese, T., Brown, P. A., Buchholz, U. J., Buchmeier, M. J., Bukreyev, A., Burt, F., Buzkan, N., Calisher, C. H., Cao, M., Casas, I., Chamberlain, J., Chandran, K., Charrel, R. N., Chen, B., Chiumenti, M., Choi, I. R., Clegg, J. C. S., Crozier, I., da Graça, J. V., Dal Bó, E., Dávila, A. M. R., de la Torre, J. C., de Lamballerie, X., de Swart, R. L., Di Bello, P. L., Di Paola, N., Di Serio, F., Dietzgen, R. G., Digiaro, M., Dolja, V. V., Dolnik, O., Drebot, M. A., Drexler, J. F., Dürrwald, R., Dufkova, L., Dundon, W. G., Duprex, W. P., Dye, J. M., Easton, A. J., Ebihara, H., Elbeaino, T., Ergünay, K., Fernandes, J., Fooks, A. R., Formenty, P. B. H., Forth, L. F., Fouchier, R. A. M., Freitas-Astúa, J., Gago-Zachert, S., Gāo, G. F., García, M. L., García-Sastre, A., Garrison, A. R., Gbakima, A., Goldstein, T., Gonzalez, J. P. J., Griffiths, A., Groschup, M. H., Günther, S., Guterres, A., Hall, R. A., Hammond, J., Hassan, M., Hepojoki, J., Hepojoki, S., Hetzel, U., Hewson, R., Hoffmann, B., Hongo, S., Höper, D., Horie, M., Hughes, H. R., Hyndman, T. H., Jambai, A., Jardim, R., Jiāng, D., Jin, Q., Jonson, G. B., Junglen, S., Karadağ, S., Keller, K. E., Klempa, B., Klingström, J., Kobinger, G., Kondō, H., Koonin, E. V., Krupovic, M., Kurath, G., Kuzmin, I. V., Laenen, L., Lamb, R. A., Lambert, A. J., Langevin, S. L., Lee, B., Lemos, E. R. S., Leroy, E. M., Li, D., Lǐ, J., Liang, M., Liú, W., Liú, Y., Lukashevich, I. S., Maes, P., Marciel de Souza, W., Marklewitz, M., Marshall, S. H., Martelli, G. P., Martin, R. R., Marzano, S. Y. L., Massart, S., McCauley, J. W., Mielke-Ehret, N., Minafra, A., Minutolo, M., Mirazimi, A., Mühlbach, H. P., Mühlberger, E., Naidu, R., Natsuaki, T., Navarro, B., Navarro, J. A., Netesov, S. V., Neumann, G., Nowotny, N., Nunes, M. R. T., Nylund, A., Økland, A. L., Oliveira, R. C., Palacios, G., Pallas, V., Pályi, B., Papa, A., Parrish, C. R., Pauvolid-Corrêa, A., Pawęska, J. T., Payne, S., Pérez, D. R., Pfaff, F., Radoshitzky, S. R., Rahman, A. U., Ramos-González, P. L., Resende, R. O., Reyes, C. A., Rima, B. K., Romanowski, V., Robles Luna, G., Rota, P., Rubbenstroth, D., Runstadler, J. A., Ruzek, D., Sabanadzovic, S., Salát, J., Sall, A. A., Salvato, M. S., Sarpkaya, K., Sasaya, T., Schwemmle, M., Shabbir, M. Z., Shí, X., Shí, Z., Shirako, Y., Simmonds, P., Širmarová, J., Sironi, M., Smither, S., Smura, T., Song, J. W., Spann, K. M., Spengler, J. R., Stenglein, M. D., Stone, D. M., Straková, P., Takada, A., Tesh, R. B., Thornburg, N. J., Tomonaga, K., Tordo, N., Towner, J. S., Turina, M., Tzanetakis, I., Ulrich, R. G., Vaira, A. M., van den Hoogen, B., Varsani, A., Vasilakis, N., Verbeek, M., Wahl, V., Walker, P. J., Wang, H., Wang, J., Wang, X., Wang, L. F., Wèi, T., Wells, H., Whitfield, A. E., Williams, J. V., Wolf, Y. I., Wú, Z., Yang, X., Yáng, X., Yu, X., Yutin, N., Zerbini, F. M., Zhang, T., Zhang, Y. Z., Zhou, G. & Zhou, X., 1 Dec 2020, In: Archives of Virology. 165, 12, p. 3023-3072 50 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    157 Scopus citations
  • A cross-reactive mouse monoclonal antibody against rhinovirus mediates phagocytosis in vitro

    Behzadi, M. A., Choi, A., Duehr, J., Feyznezhad, R., Upadhyay, C., Schotsaert, M., Palese, P. & Nachbagauer, R., 1 Dec 2020, In: Scientific Reports. 10, 1, 9750.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Activity of human serum antibodies in an influenza virus hemagglutinin stalk-based ADCC reporter assay correlates with activity in a CD107a degranulation assay

    Chromikova, V., Tan, J., Aslam, S., Rajabhathor, A., Bermudez-Gonzalez, M., Ayllon, J., Simon, V., García-Sastre, A., Salaun, B., Nachbagauer, R. & Krammer, F., 18 Feb 2020, In: Vaccine. 38, 8, p. 1953-1961 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • A genome-wide CRISPR-Cas9 screen reveals the requirement of host cell sulfation for schmallenberg virus infection

    Thamamongood, T., Aebischer, A., Wagner, V., Chang, M. W., Elling, R., Benner, C., García-Sastre, A., Kochs, G., Beer, M. & Schwemmle, M., Sep 2020, In: Journal of Virology. 94, 17, e00752-20.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • A high-throughput assay for circulating antibodies directed against the s protein of severe acute respiratory syndrome coronavirus 2

    Weiss, S., Klingler, J., Hioe, C., Amanat, F., Baine, I., Arinsburg, S., Kojic, E. M., Stoever, J., Liu, S. T. H., Jurczyszak, D., Bermudez-Gonzalez, M., Simon, V., Krammer, F. & Zolla-Pazner, S., 15 Nov 2020, In: Journal of Infectious Diseases. 222, 10, p. 1629-1634 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids

    Yang, L., Han, Y., Nilsson-Payant, B. E., Gupta, V., Wang, P., Duan, X., Tang, X., Zhu, J., Zhao, Z., Jaffré, F., Zhang, T., Kim, T. W., Harschnitz, O., Redmond, D., Houghton, S., Liu, C., Naji, A., Ciceri, G., Guttikonda, S., Bram, Y., & 17 othersNguyen, D. H. T., Cioffi, M., Chandar, V., Hoagland, D. A., Huang, Y., Xiang, J., Wang, H., Lyden, D., Borczuk, A., Chen, H. J., Studer, L., Pan, F. C., Ho, D. D., tenOever, B. R., Evans, T., Schwartz, R. E. & Chen, S., 2 Jul 2020, In: Cell Stem Cell. 27, 1, p. 125-136.e7

    Research output: Contribution to journalArticlepeer-review

    Open Access
    473 Scopus citations
  • A newcastle disease virus (NDV) expressing a membrane-anchored spike as a cost-effective inactivated SARS-CoV-2 vaccine

    Sun, W., McCroskery, S., Liu, W. C., Leist, S. R., Liu, Y., Albrecht, R. A., Slamanig, S., Oliva, J., Amanat, F., Schäfer, A., Dinnon, K. H., Innis, B. L., García-Sastre, A., Krammer, F., Baric, R. S. & Palese, P., Dec 2020, In: Vaccines. 8, 4, p. 1-14 14 p., 771.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    51 Scopus citations
  • Animal models for COVID-19

    Muñoz-Fontela, C., Dowling, W. E., Funnell, S. G. P., Gsell, P. S., Riveros-Balta, A. X., Albrecht, R. A., Andersen, H., Baric, R. S., Carroll, M. W., Cavaleri, M., Qin, C., Crozier, I., Dallmeier, K., de Waal, L., de Wit, E., Delang, L., Dohm, E., Duprex, W. P., Falzarano, D., Finch, C. L., & 44 othersFrieman, M. B., Graham, B. S., Gralinski, L. E., Guilfoyle, K., Haagmans, B. L., Hamilton, G. A., Hartman, A. L., Herfst, S., Kaptein, S. J. F., Klimstra, W. B., Knezevic, I., Krause, P. R., Kuhn, J. H., Le Grand, R., Lewis, M. G., Liu, W. C., Maisonnasse, P., McElroy, A. K., Munster, V., Oreshkova, N., Rasmussen, A. L., Rocha-Pereira, J., Rockx, B., Rodríguez, E., Rogers, T. F., Salguero, F. J., Schotsaert, M., Stittelaar, K. J., Thibaut, H. J., Tseng, C. T., Vergara-Alert, J., Beer, M., Brasel, T., Chan, J. F. W., García-Sastre, A., Neyts, J., Perlman, S., Reed, D. S., Richt, J. A., Roy, C. J., Segalés, J., Vasan, S. S., Henao-Restrepo, A. M. & Barouch, D. H., 22 Oct 2020, In: Nature. 586, 7830, p. 509-515 7 p.

    Research output: Contribution to journalReview articlepeer-review

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    560 Scopus citations
  • An In Vitro Microneutralization Assay for SARS-CoV-2 Serology and Drug Screening

    Amanat, F., White, K. M., Miorin, L., Strohmeier, S., McMahon, M., Meade, P., Liu, W. C., Albrecht, R. A., Simon, V., Martinez-Sobrido, L., Moran, T., García-Sastre, A. & Krammer, F., 1 Sep 2020, In: Current Protocols in Microbiology. 58, 1, e108.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    118 Scopus citations
  • A novel SUMOylation site in the influenza a virus NS1 protein identified with a highly sensitive FRET assay

    Way, G., Xiong, Z., Wang, G., Dai, H., Zheng, S., García-Sastre, A. & Liao, J., 10 Nov 2020, In: Journal of Biotechnology. 323, p. 121-127 7 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

    Schoof, M., Faust, B., Saunders, R. A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesbølle, C. B., Puchades, C., Azumaya, C. M., Kratochvil, H. T., Zimanyi, M., Deshpande, I., Liang, J., Dickinson, S., Nguyen, H. C., Chio, C. M., Merz, G. E., Thompson, M. C., Diwanji, D., & 36 othersSchaefer, K., Anand, A. A., Dobzinski, N., Zha, B. S., Simoneau, C. R., Leon, K., White1, K. M., Chio, U. S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A. M., Rizo, A. N., Moss, F., Brilot, A. F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill1, A. W., Nock, S., Liu, Y., Krogan, N. J., Ralston, C. Y., Swaney, D. L., Garciá-Sastre, A., Ott, M., Vignuzzi, M., Walter, P. & Manglik, A., 18 Dec 2020, In: Science. 370, 6523, p. 1473-1479 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    265 Scopus citations
  • A Quantitative Genetic Interaction Map of HIV Infection

    Gordon, D. E., Watson, A., Roguev, A., Zheng, S., Jang, G. M., Kane, J., Xu, J., Guo, J. Z., Stevenson, E., Swaney, D. L., Franks-Skiba, K., Verschueren, E., Shales, M., Crosby, D. C., Frankel, A. D., Marson, A., Marazzi, I., Cagney, G. & Krogan, N. J., 16 Apr 2020, In: Molecular Cell. 78, 2, p. 197-209.e7

    Research output: Contribution to journalArticlepeer-review

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    14 Scopus citations
  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

    Gordon, D. E., Jang, G. M., Bouhaddou, M., Xu, J., Obernier, K., White, K. M., O’Meara, M. J., Rezelj, V. V., Guo, J. Z., Swaney, D. L., Tummino, T. A., Hüttenhain, R., Kaake, R. M., Richards, A. L., Tutuncuoglu, B., Foussard, H., Batra, J., Haas, K., Modak, M., Kim, M., & 105 othersHaas, P., Polacco, B. J., Braberg, H., Fabius, J. M., Eckhardt, M., Soucheray, M., Bennett, M. J., Cakir, M., McGregor, M. J., Li, Q., Meyer, B., Roesch, F., Vallet, T., Mac Kain, A., Miorin, L., Moreno, E., Naing, Z. Z. C., Zhou, Y., Peng, S., Shi, Y., Zhang, Z., Shen, W., Kirby, I. T., Melnyk, J. E., Chorba, J. S., Lou, K., Dai, S. A., Barrio-Hernandez, I., Memon, D., Hernandez-Armenta, C., Lyu, J., Mathy, C. J. P., Perica, T., Pilla, K. B., Ganesan, S. J., Saltzberg, D. J., Rakesh, R., Liu, X., Rosenthal, S. B., Calviello, L., Venkataramanan, S., Liboy-Lugo, J., Lin, Y., Huang, X. P., Liu, Y. F., Wankowicz, S. A., Bohn, M., Safari, M., Ugur, F. S., Koh, C., Savar, N. S., Tran, Q. D., Shengjuler, D., Fletcher, S. J., O’Neal, M. C., Cai, Y., Chang, J. C. J., Broadhurst, D. J., Klippsten, S., Sharp, P. P., Wenzell, N. A., Kuzuoglu-Ozturk, D., Wang, H. Y., Trenker, R., Young, J. M., Cavero, D. A., Hiatt, J., Roth, T. L., Rathore, U., Subramanian, A., Noack, J., Hubert, M., Stroud, R. M., Frankel, A. D., Rosenberg, O. S., Verba, K. A., Agard, D. A., Ott, M., Emerman, M., Jura, N., von Zastrow, M., Verdin, E., Ashworth, A., Schwartz, O., d’Enfert, C., Mukherjee, S., Jacobson, M., Malik, H. S., Fujimori, D. G., Ideker, T., Craik, C. S., Floor, S. N., Fraser, J. S., Gross, J. D., Sali, A., Roth, B. L., Ruggero, D., Taunton, J., Kortemme, T., Beltrao, P., Vignuzzi, M., García-Sastre, A., Shokat, K. M., Shoichet, B. K. & Krogan, N. J., 16 Jul 2020, In: Nature. 583, 7816, p. 459-468 10 p.

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    2936 Scopus citations
  • A serological assay to detect SARS-CoV-2 seroconversion in humans

    Amanat, F., Stadlbauer, D., Strohmeier, S., Nguyen, T. H. O., Chromikova, V., McMahon, M., Jiang, K., Arunkumar, G. A., Jurczyszak, D., Polanco, J., Bermudez-Gonzalez, M., Kleiner, G., Aydillo, T., Miorin, L., Fierer, D. S., Lugo, L. A., Kojic, E. M., Stoever, J., Liu, S. T. H., Cunningham-Rundles, C., & 10 othersFelgner, P. L., Moran, T., García-Sastre, A., Caplivski, D., Cheng, A. C., Kedzierska, K., Vapalahti, O., Hepojoki, J. M., Simon, V. & Krammer, F., 1 Jul 2020, In: Nature Medicine. 26, 7, p. 1033-1036 4 p.

    Research output: Contribution to journalArticlepeer-review

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    1180 Scopus citations
  • Author Correction: Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection (Nature Communications, (2020), 11, 1, (2537), 10.1038/s41467-020-16429-9)

    Kaul, D., Rathnasinghe, R., Ferres, M., Tan, G. S., Barrera, A., Pickett, B. E., Methe, B. A., Das, S. R., Budnik, I., Halpin, R. A., Wentworth, D., Schmolke, M., Mena, I., Albrecht, R. A., Singh, I., Nelson, K. E., García-Sastre, A., Dupont, C. L. & Medina, R. A., 1 Dec 2020, In: Nature Communications. 11, 1, 3132.

    Research output: Contribution to journalComment/debate

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    4 Scopus citations
  • Characterizing emerging canine H3 influenza viruses

    Martinez-Sobrido, L., Blanco-Lobo, P., Rodriguez, L., Fitzgerald, T., Zhang, H., Nguyen, P., Anderson, C. S., Holden-Wiltse, J., Bandyopadhyay, S., Nogales, A., DeDiego, M. L., Wasik, B. R., Miller, B. L., Henry, C., Wilson, P. C., Sangster, M. Y., Treanor, J. J., Topham, D. J., Byrd-Leotis, L., Steinhauer, D. A., & 64 othersCummings, R. D., Luczo, J. M., Tompkins, S. M., Sakamoto, K., Jones, C. A., Steel, J., Lowen, A. C., Danzy, S., Tao, H., Fink, A. L., Klein, S. L., Wohlgemuth, N., Fenstermacher, K. J., el Najjar, F., Pekosz, A., Sauer, L., Lewis, M. K., Shaw-Saliba, K., Rothman, R. E., Liu, Z. Y., Chen, K. F., Parrish, C. R., Voorhees, I. E. H., Kawaoka, Y., Neumann, G., Chiba, S., Fan, S., Hatta, M., Kong, H., Zhong, G., Wang, G., Uccellini, M. B., García-Sastre, A., Perez, D. R., Ferreri, L. M., Herfst, S., Richard, M., Fouchier, R., Burke, D., Pattinson, D., Smith, D. J., Meliopoulos, V., Freiden, P., Livingston, B., Sharp, B., Cherry, S., Dib, J. C., Yang, G., Russell, C. J., Barman, S., Webby, R. J., Krauss, S., Danner, A., Woodard, K., Peiris, M., Perera, R. A. P. M., Chan, M. C. W., Govorkova, E. A., Marathe, B. M., Pascua, P. N. Q., Smith, G., Li, Y. T., Thomas, P. G. & Schultz-Cherry, S., Apr 2020, In: PLoS Pathogens. 16, 4, e1008409.

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    23 Scopus citations
  • Chemical intervention of influenza virus mRNA nuclear export

    Esparza, M., Mor, A., Niederstrasser, H., White, K., White, A., Zhang, K., Gao, S., Wang, J., Liang, J., Sho, S., Sakthivel, R., Sathe, A. A., Xing, C., Muñoz-Moreno, R., Shay, J. W., García-Sastre, A., Ready, J., Posner, B. & Fontoura, B. M. A., 1 Apr 2020, In: PLoS Pathogens. 16, 4, e1008407.

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    11 Scopus citations
  • Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

    Gordon, D. E., Hiatt, J., Bouhaddou, M., Rezelj, V. V., Ulferts, S., Braberg, H., Jureka, A. S., Obernier, K., Guo, J. Z., Batra, J., Kaake, R. M., Weckstein, A. R., Owens, T. W., Gupta, M., Pourmal, S., Titus, E. W., Cakir, M., Soucheray, M., McGregor, M., Cakir, Z., & 178 othersJang, G., O'Meara, M. J., Tummino, T. A., Zhang, Z., Foussard, H., Rojc, A., Zhou, Y., Kuchenov, D., Hüttenhain, R., Xu, J., Eckhardt, M., Swaney, D. L., Fabius, J. M., Ummadi, M., Tutuncuoglu, B., Rathore, U., Modak, M., Haas, P., Haas, K. M., Naing, Z. Z. C., Pulido, E. H., Shi, Y., Barrio-Hernandez, I., Memon, D., Petsalaki, E., Dunham, A., Marrero, M. C., Burke, D., Koh, C., Vallet, T., Silvas, J. A., Azumaya, C. M., Billesbølle, C., Brilot, A. F., Campbell, M. G., Diallo, A., Dickinson, M. S., Diwanji, D., Herrera, N., Hoppe, N., Kratochvil, H. T., Liu, Y., Merz, G. E., Moritz, M., Nguyen, H. C., Nowotny, C., Puchades, C., Rizo, A. N., Schulze-Gahmen, U., Smith, A. M., Sun, M., Young, I. D., Zhao, J., Asarnow, D., Biel, J., Bowen, A., Braxton, J. R., Chen, J., Chio, C. M., Chio, U. S., Deshpande, I., Doan, L., Faust, B., Flores, S., Jin, M., Kim, K., Lam, V. L., Li, F., Li, J., Li, Y. L., Li, Y., Liu, X., Lo, M., Lopez, K. E., Melo, A. A., Moss, F. R., Nguyen, P., Paulino, J., Pawar, K. I., Peters, J. K., Pospiech, T. H., Safari, M., Sangwan, S., Schaefer, K., Thomas, P. V., Thwin, A. C., Trenker, R., Tse, E., Tsui, T. K. M., Wang, F., Whitis, N., Yu, Z., Zhang, K., Zhang, Y., Zhou, F., Saltzberg, D., Hodder, A. J., Shun-Shion, A. S., Williams, D. M., White, K. M., Rosales, R., Kehrer, T., Miorin, L., Moreno, E., Patel, A. H., Rihn, S., Khalid, M. M., Vallejo-Gracia, A., Fozouni, P., Simoneau, C. R., Roth, T. L., Wu, D., Karim, M. A., Ghoussaini, M., Dunham, I., Berardi, F., Weigang, S., Chazal, M., Park, J., Logue, J., McGrath, M., Weston, S., Haupt, R., Hastie, C. J., Elliott, M., Brown, F., Burness, K. A., Reid, E., Dorward, M., Johnson, C., Wilkinson, S. G., Geyer, A., Giesel, D. M., Baillie, C., Raggett, S., Leech, H., Toth, R., Goodman, N., Keough, K. C., Lind, A. L., Klesh, R. J., Hemphill, K. R., Carlson-Stevermer, J., Oki, J., Holden, K., Maures, T., Pollard, K. S., Sali, A., Agard, D. A., Cheng, Y., Fraser, J. S., Frost, A., Jura, N., Kortemme, T., Manglik, A., Southworth, D. R., Stroud, R. M., Alessi, D. R., Davies, P., Frieman, M. B., Ideker, T., Abate, C., Jouvenet, N., Kochs, G., Shoichet, B., Ott, M., Palmarini, M., Shokat, K. M., García-Sastre, A., Rassen, J. A., Grosse, R., Rosenberg, O. S., Verba, K. A., Basler, C. F., Vignuzzi, M., Peden, A. A., Beltrao, P. & Krogan, N. J., 4 Dec 2020, In: Science. 370, 6521, eabe9403.

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    Open Access
    432 Scopus citations
  • Comparison of transgenic and adenovirus hACE2 mouse models for SARS-CoV-2 infection

    Rathnasinghe, R., Strohmeier, S., Amanat, F., Gillespie, V. L., Krammer, F., García-Sastre, A., Coughlan, L., Schotsaert, M. & Uccellini, M. B., 2020, In: Emerging Microbes and Infections. 9, 1, p. 2433-2445 13 p.

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    109 Scopus citations
  • 14 Scopus citations