Mount Sinai Global Health and Emerging Pathogens Institute

Icahn School of Medicine at Mount Sinai

102956 Citations
158 h-index
876 Article
67 Review article
47 Comment/debate
24 Letter
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Addressing SARS-CoV-2 evolution: neutralization of emerging variants of concern by the AVX/COVID-12 ‘Patria’ vaccine based on HexaPro-S ancestral Wuhan spike or its updated BA.2.75.2 version
Carballo-Uicab, G., Mellado-Sánchez, G., González-González, E., Salinas-Trujano, J., Mendoza-Salazar, I., López-Olvera, K., Gómez-Castellano, K. M., Salazar, M. I., Torres-Flores, J. M., Chagoya-Cortés, H. E., Paz-De la Rosa, G., Mena, I., Rojas-Martínez, O., Lara-Puente, J. H., Peralta-Sánchez, G. J., Sarfati-Mizrahi, D., Torres-Flores, A., Sun, W., Krammer, F. & García-Sastre, A. & 5 others, Palese, P., López-Macías, C., Lozano-Dubernard, B., Pérez-Tapia, S. M. & Almagro, J. C., 2025, In: Frontiers in Immunology. 16, 1565934.
Research output: Contribution to journal › Article › peer-review
A live attenuated NS1-deficient vaccine candidate for cattle-origin influenza A (H5N1) clade 2.3.4.4.b viruses
Mostafa, A., Ye, C., Barre, R. S., Shivanna, V., Meredith, R., Platt, R. N., Escobedo, R. A., Bayoumi, M., Castro, E. M., Jackson, N., Cupic, A., Nogales, A., Anderson, T. J. C., García-Sastre, A. & Martinez-Sobrido, L., Dec 2025, In: npj Vaccines. 10, 1, 151.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
An integrated approach for the accurate detection of HERV-K HML-2 transcription and protein synthesis
Gleason, C., Terry, S. N., Hernandez, M. M., Jacob, S., Fenyo, D., Johnson, J. R., Deikus, G., Francoeur, N., Hahn, A., Sebra, R., Zamarin, D., Molina, H., Simon, V. & Mulder, L. C. F., 27 Jan 2025, In: Nucleic Acids Research. 53, 2, gkaf011.
Research output: Contribution to journal › Article › peer-review

Open Access
An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection
Walter, Z., Li, M., Molho, M., Berish, L., Isopi, A., O'Mara, M., Dittmar, M., Nwaezeapu, C., Richards, A., McCullagh, M., Krogan, N. J., Cherry, S., Johnson, J. R. & Ramage, H., 27 May 2025, In: Cell Reports. 44, 5, 115728.
Research output: Contribution to journal › Article › peer-review
Annual (2024) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)
Kuhn, J. H., Adkins, S., Alkhovsky, S. V., An, W., Avšič-Županc, T., Ayllón, M. A., Bačnik, K., Bahl, J., Balkema-Buschmann, A., Ballinger, M. J., Beer, M., Bejerman, N., Bergeron, É., Biedenkopf, N., Blair, C. D., Blasdell, K. R., Bradfute, S. B., Briese, T., Brown, K. & Brown, P. A. & 168 others, Buchholz, U. J., Buchmeier, M. J., Bukreyev, A., Burt, F., Calisher, C. H., Calvelage, S., Cao, M., Casas, I., Chabi-Jesus, C., Chandran, K., Charrel, R. N., Crane, A., Cuypers, L. N., Bó, E. D., de la Torre, J. C., de Souza, W. M., de Swart, R. L., Debat, H. J., Dheilly, N. M., Paola, N. D., Serio, F. D., Dietzgen, R. G., Digiaro, M., Felix Drexler, J., Paul Duprex, W., Dürrwald, R., Easton, A. J., Elbeaino, T., Ergünay, K., Eshak, M. I. Y., Feng, G., Firth, A. E., Fooks, A. R., Formenty, P. B. H., Freitas-Astúa, J., Freuling, C. M., Gadd, T., Gago-Zachert, S., García, M. L., García-Sastre, A., Garrison, A. R., Goldberg, T. L., Gonzalez, J. P. J., de Bellocq, J. G., Griffiths, A., Groschup, M. H., Gryseels, S., Gutiérrez-Aguirre, I., Günther, S., Hammond, J., Hepojoki, J., Horie, M., Hume, A. J., Hyndman, T. H., Höper, D., Jiāng, D., Junglen, S., Klempa, B., Klingström, J., Kondō, H., Koonin, E. V., Krupovic, M., Kubota, K., Kurath, G., Kutnjak, D., Laenen, L., Lambert, A. J., Lee, B., Li, C., Lǐ, J., Li, J. M., Lukashevich, I. S., Maes, P., Marklewitz, M., Marshall, S. H., Marzano, S. Y. L., McCauley, J. W., Mehle, N., Mirazimi, A., Morikawa, T., Mühlberger, E., Müller, T., Naidu, R., Natsuaki, T., Navarro, B., Navarro, J. A., Neriya, Y., Netesov, S. V., Nicoloso, V. M., Neumann, G., Nokireki, T., Nowotny, N., Nunes, M. R. T., Ochoa-Corona, F. M., Palacios, G., Pallás, V., Papa, A., Paraskevopoulou, S., Parrish, C. R., Pauvolid-Corrêa, A., Pecman, A., Pérez, D. R., Pfaff, F., Plemper, R. K., Postler, T. S., Radoshitzky, S. R., Ramos-González, P. L., Ravnikar, M., Resende, R. O., Reuter, G., Reyes, C. A., Rivarez, M. P. S., Romanowski, V., Rubbenstroth, D., Rubino, L., Runstadler, J. A., Ruiz-Padilla, A., Sabanadzovic, S., Salvato, M. S., Sasaya, T., Schmaljohn, C. S., Schmidt-Posthaus, H., Schwemmle, M., Seljak, G., Seuberlich, T., Shi, M., Shimomoto, Y., Simmonds, P., Sironi, M., Smith, D. B., Smither, S., Song, J. W., Spann, K. M., Spengler, J. R., Stenglein, M. D., Takada, A., Takemura, C., Tammiranta, N., Tesh, R. B., Thornburg, N. J., Tischler, N. D., Tomitaka, Y., Tomonaga, K., Tordo, N., Turina, M., Tzanetakis, I. E., Vaira, A. M., van den Hoogen, B., Vanmechelen, B., Vasilakis, N., Verbeek, M., von Bargen, S., Vučurović, A., Wada, J., Wahl, V., Walker, P. J., Wang, F., Whitfield, A. E., Williams, J. V., Wolf, Y. I., Yanagisawa, H., Yang, C., Ye, G., Yu, M. C., Zerbini, F. M., Zhang, S., Økland, A. L. & Hughes, H. R., 2025, In: Journal of General Virology. 106, 6, 002077.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
A single immunization with intranasal Newcastle disease virus (NDV)-based XBB.1.5 variant vaccine reduces disease and transmission in animals against matched-variant challenge
Slamanig, S., Lemus, N., Lai, T. Y., Singh, G., Mishra, M., Abdeljawad, A., Boza, M., Dolange, V., Singh, G., Lee, B., González-Domínguez, I., Schotsaert, M., Krammer, F., Palese, P. & Sun, W., 25 Jan 2025, In: Vaccine. 45, 126586.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
A Surrogate Enzyme-Linked Immunosorbent Assay to Select High-Titer Human Convalescent Plasma for Treating Immunocompromised Patients Infected With Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern
Dolange, V., Slamanig, S., Abdeljawad, A., Lai, T. Y., Lemus, N., Singh, G., Carreño, J. M., Abbad, A., Srivastava, K., Simon, V., Sachithanandham, J., Pekosz, A., Sullivan, D., Krammer, F., Sun, W., Palese, P. & González-Domínguez, I., 15 Apr 2025, In: Journal of Infectious Diseases. 231, 4, p. e723-e733
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
A ventilated perfused lung model platform to dissect the response of the lungs to viral infection
Derman, I. D., Alioglu, M. A., Moses, J. C., Chroneos, Z. C., Yilmaz, Y. O., Banerjee, D., Koff, J., Rizvi, S. H. A., Klunk, D. N., Celik, N., Pochareddy, S., Umstead, T. M., Namli, I., Holton, S. E., Mikacenic, C., Thompson, J. L., Castaneda, D. C., Hickey, D. R., Nagamine, M. & Warang, P. & 5 others, Schotsaert, M., Chen, P., Peeples, M. E., Palucka, K. & Ozbolat, I. T., Jul 2025, In: Trends in Biotechnology. 43, 7, p. 1714-1742 29 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza
Soni, S., Yildiz, S., Allen, E. K., Petersen, H., Peeples, M., Zahed, S. E., Rosas, L., Anang, V., Antonescu, L., Nho, R. S., Mora, A. L., Horowitz, J. C., Rojas, M., Medina, R. A., Thomas, P. G., García-Sastre, A., Tesfaigzi, Y. & Mebratu, Y. A., 15 Jul 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 28, e2424367122.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Co-administration of seasonal quadrivalent influenza and COVID-19 vaccines leads to enhanced immune responses to influenza virus and reduced immune responses to SARS-CoV-2 in naive mice
Abbad, A., Yueh, J., Yellin, T., Singh, G., Carreño, J. M., Clark, J. J., Muramatsu, H., Tiwari, S., Bhavsar, D., Alzua, G. P., Pardi, N., Simon, V. & Krammer, F., 19 Mar 2025, In: Vaccine. 50, 126825.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Contrasting interferon-mediated antiviral responses in human lung adenocarcinoma cells
Esparza, M., El Zahed, S. S., Karakus, U., Niederstrasser, H., Gao, B., Batten, K., Shay, J. W., Posner, B., Hirsch, F. R., Girard, L., Huang, L. J. S., Minna, J., García-Sastre, A. & Fontoura, B. M. A., Jun 2025, In: Journal of Virology. 99, 6, e00469-25.
Research output: Contribution to journal › Article › peer-review
Correction to: Virus-induced senescence is a driver and therapeutic target in COVID-19 (Nature, (2021), 599, 7884, (283-289), 10.1038/s41586-021-03995-1)
Lee, S., Yu, Y., Trimpert, J., Benthani, F., Mairhofer, M., Richter-Pechanska, P., Wyler, E., Belenki, D., Kaltenbrunner, S., Pammer, M., Kausche, L., Firsching, T. C., Dietert, K., Schotsaert, M., Martínez-Romero, C., Singh, G., Kunz, S., Niemeyer, D., Ghanem, R. & Salzer, H. J. F. & 28 others, Paar, C., Mülleder, M., Uccellini, M., Michaelis, E. G., Khan, A., Lau, A., Schönlein, M., Habringer, A., Tomasits, J., Adler, J. M., Kimeswenger, S., Gruber, A. D., Hoetzenecker, W., Steinkellner, H., Purfürst, B., Motz, R., Di Pierro, F., Lamprecht, B., Osterrieder, N., Landthaler, M., Drosten, C., García-Sastre, A., Langer, R., Ralser, M., Eils, R., Reimann, M., Fan, D. N. Y. & Schmitt, C. A., 27 Feb 2025, In: Nature. 638, 8052, p. E46
Research output: Contribution to journal › Comment/debate
1 Scopus citations

Research on Proteins Published by Researchers at University of California (Structures of Native Doublet Microtubules from Trichomonas vaginalis Reveal Parasite-Specific Proteins)
Johnson, J.
19/05/25
1 item of Media coverage
Press/Media
St. Jude Children's Research Hospital: Infant immune systems respond differently to severe COVID-19
Aydillo-Gomez, T., Miorin, L. & Garcia-Sastre, A.
16/05/25 → 17/05/25
2 items of Media coverage
Press/Media
Infant immune systems respond differently to severe COVID-19
Aydillo-Gomez, T., Miorin, L. & Garcia-Sastre, A.
16/05/25
2 items of Media coverage
Press/Media
Investigators from University of California San Francisco (UCSF) Target Chlamydia (The Chlamydia Effector Dre1 Binds Dynactin To Reposition Host Organelles During Infection)
Krogan, N. & Johnson, J.
9/05/25
1 item of Media coverage
Press/Media
Eric J. Nestler, MD, PhD, leading brain scientist and Interim Dean of the Icahn School of Medicine at Mount Sinai, elected to the National Academy of Sciences
Merad, M., Nestler, E. J., Carr, B., Palese, P., Garcia-Sastre, A., Charney, D., Mayberg,, H. & Hurd, Y.
5/05/25
1 item of Media coverage
Press/Media
Eric J. Nestler, MD, PhD, Leading Brain Scientist and Interim Dean of the Icahn School of Medicine at Mount Sinai, Elected to the National Academy of Sciences
Merad, M., Nestler, E. J., Carr, B., Palese, P., Charney, D., Mayberg,, H., Hurd, Y. & Garcia-Sastre, A.
2/05/25
1 item of Media coverage
Press/Media
Lung Immune Cell Type “Quietly” Controls Inflammation in COVID-19
tenOever,, B.
28/04/25
1 item of Media coverage
Press/Media
The Hidden Role of NAMs in Protecting Lungs From COVID-19
tenOever,, B.
28/04/25
1 item of Media coverage
Press/Media
HMN 2025: How Rare lung immune cells act as peacekeepers in opposition to lethal COVID-19 irritation
tenOever,, B.
28/04/25
1 item of Media coverage
Press/Media
Immune Cells: Deciding Life and Death
tenOever,, B.
26/04/25
1 item of Media coverage
Press/Media
NYU Langone Health: Lung Immune Cell Type Quietly Controls Inflammation in COVID-19
tenOever,, B.
25/04/25
9 items of Media coverage
Press/Media
Lung Immune Cell Type Quietly Controls Inflammation In COVID-19
tenOever,, B.
25/04/25
66 items of Media coverage
Press/Media

Mount Sinai Global Health and Emerging Pathogens Institute

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Adolfo Garcia-Sastre

Jeffrey Johnson

Michael Schotsaert

Viviana Simon

Addressing SARS-CoV-2 evolution: neutralization of emerging variants of concern by the AVX/COVID-12 ‘Patria’ vaccine based on HexaPro-S ancestral Wuhan spike or its updated BA.2.75.2 version

A live attenuated NS1-deficient vaccine candidate for cattle-origin influenza A (H5N1) clade 2.3.4.4.b viruses

An integrated approach for the accurate detection of HERV-K HML-2 transcription and protein synthesis

An integrated proteomics approach identifies phosphorylation sites on viral and host proteins that regulate West Nile virus infection

Annual (2024) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)

A single immunization with intranasal Newcastle disease virus (NDV)-based XBB.1.5 variant vaccine reduces disease and transmission in animals against matched-variant challenge

A Surrogate Enzyme-Linked Immunosorbent Assay to Select High-Titer Human Convalescent Plasma for Treating Immunocompromised Patients Infected With Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern

A ventilated perfused lung model platform to dissect the response of the lungs to viral infection

BIK polymorphism and proteasome regulation unveil host risk factor for severe influenza

Co-administration of seasonal quadrivalent influenza and COVID-19 vaccines leads to enhanced immune responses to influenza virus and reduced immune responses to SARS-CoV-2 in naive mice

Contrasting interferon-mediated antiviral responses in human lung adenocarcinoma cells

Correction to: Virus-induced senescence is a driver and therapeutic target in COVID-19 (Nature, (2021), 599, 7884, (283-289), 10.1038/s41586-021-03995-1)

Research on Proteins Published by Researchers at University of California (Structures of Native Doublet Microtubules from Trichomonas vaginalis Reveal Parasite-Specific Proteins)

St. Jude Children's Research Hospital: Infant immune systems respond differently to severe COVID-19

Infant immune systems respond differently to severe COVID-19

Investigators from University of California San Francisco (UCSF) Target Chlamydia (The Chlamydia Effector Dre1 Binds Dynactin To Reposition Host Organelles During Infection)

Eric J. Nestler, MD, PhD, leading brain scientist and Interim Dean of the Icahn School of Medicine at Mount Sinai, elected to the National Academy of Sciences

Eric J. Nestler, MD, PhD, Leading Brain Scientist and Interim Dean of the Icahn School of Medicine at Mount Sinai, Elected to the National Academy of Sciences

Lung Immune Cell Type “Quietly” Controls Inflammation in COVID-19

The Hidden Role of NAMs in Protecting Lungs From COVID-19

HMN 2025: How Rare lung immune cells act as peacekeepers in opposition to lethal COVID-19 irritation

Immune Cells: Deciding Life and Death

NYU Langone Health: Lung Immune Cell Type Quietly Controls Inflammation in COVID-19

Lung Immune Cell Type Quietly Controls Inflammation In COVID-19

Mount Sinai Global Health and Emerging Pathogens Institute

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Press/Media