Mount Sinai Drug Discovery Institute

Icahn School of Medicine at Mount Sinai

2990 Citations
25 h-index
46 Article
13 Short survey
11 Review article
10 Comment/debate
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- 2 Chapter

A master regulator of opioid reward in the ventral prefrontal cortex
Smith, A. C. W., Ghoshal, S., Centanni, S. W., Heyer, M. P., Corona, A., Wills, L., Andraka, E., Lei, Y., O'Connor, R. M., Caligiuri, S. P. B., Khan, S., Beaumont, K., Sebra, R. P., Kieffer, B. L., Winder, D. G., Ishikawa, M. & Kenny, P. J., 7 Jun 2024, In: Science. 384, 6700, p. eadn0886
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
Generative artificial intelligence-enabled dynamic detection of rat nicotine-related circuits
Gong, C., Jing, C., Liu, X. A., Wang, V. X., Tang, C. Y., Kenny, P. J., Li, Y., Chen, Z. & Wang, S., Mar 2024, In: Neural Computing and Applications. 36, 9, p. 4693-4707 15 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Hypothalamic CRF neurons facilitate brain reward function
Xu, X., Zheng, S., Ren, J., Li, Z., Li, J., Xu, Z., Yuan, F., Yang, Q., Margetts, A. V., Pollock, T. A., Vilca, S. J., Yang, C., Chen, G., Shen, P., Li, S., Xia, J., Chen, C., Zhou, T., Zhu, Y. & Tuesta, L. M. & 4 others, Wang, L., Kenny, P. J., Liu, X. A. & Chen, Z., 22 Jan 2024, In: Current Biology. 34, 2, p. 389-402.e5
Research output: Contribution to journal › Article › peer-review

Open Access
8 Scopus citations
Precise 3D Localization of Intracerebral Implants Using a Simple Brain Clearing Method
Catanese, J., Murakami, T. C., Catto, A., Kenny, P. J. & Ibañez-Tallon, I., Nov 2024, In: Journal of Integrative Neuroscience. 23, 11, 207.
Research output: Contribution to journal › Article › peer-review

Open Access
SR9883 is a novel small-molecule enhancer of α4β2* nicotinic acetylcholine receptor signaling that decreases intravenous nicotine self-administration in rats
Braunscheidel, K. M., Voren, G., Fowler, C. D., Lu, Q., Kuryatov, A., Cameron, M. D., Ibañez-Tallon, I., Lindstrom, J. M., Kamenecka, T. M. & Kenny, P. J., 2024, In: Frontiers in Molecular Neuroscience. 17, 1459098.
Research output: Contribution to journal › Article › peer-review

Open Access
The single-cell opioid responses in the context of HIV (SCORCH) consortium
Ament, S. A., Campbell, R. R., Lobo, M. K., Receveur, J. P., Agrawal, K., Borjabad, A., Byrareddy, S. N., Chang, L., Clarke, D., Emani, P., Gabuzda, D., Gaulton, K. J., Giglio, M., Giorgi, F. M., Gok, B., Guda, C., Hadas, E., Herb, B. R., Hu, W. & Huttner, A. & 57 others, Ishmam, M. R., Jacobs, M. M., Kelschenbach, J., Kim, D. W., Lee, C., Liu, S., Liu, X., Madras, B. K., Mahurkar, A. A., Mash, D. C., Mukamel, E. A., Niu, M., O’Connor, R. M., Pagan, C. M., Pang, A. P. S., Pillai, P., Repunte-Canonigo, V., Ruzicka, W. B., Stanley, J., Tickle, T., Tsai, S. Y. A., Wang, A., Wills, L., Wilson, A. M., Wright, S. N., Xu, S., Yang, J., Zand, M., Zhang, L., Zhang, J., Akbarian, S., Buch, S., Cheng, C. S., Corley, M. J., Fox, H. S., Gerstein, M., Gummuluru, S., Heiman, M., Ho, Y. C., Kellis, M., Kenny, P. J., Kluger, Y., Milner, T. A., Moore, D. J., Morgello, S., Ndhlovu, L. C., Rana, T. M., Sanna, P. P., Satterlee, J. S., Sestan, N., Spector, S. A., Spudich, S., Tilgner, H. U., Volsky, D. J., White, O. R., Williams, D. W. & Zeng, H., Dec 2024, In: Molecular Psychiatry. 29, 12, p. 3950-3961 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
Central and peripheral actions of nicotine that influence blood glucose homeostasis and the development of diabetes
Chen, Z., Liu, X. A. & Kenny, P. J., Aug 2023, In: Pharmacological Research. 194, 106860.
Research output: Contribution to journal › Article › peer-review

Open Access
18 Scopus citations
New medications development for smoking cessation
Lengel, D. & Kenny, P. J., Sep 2023, In: Addiction Neuroscience. 7, 100103.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
The Neurobiology of Eating Behavior in Obesity: Mechanisms and Therapeutic Targets: A Report from the 23rd Annual Harvard Nutrition Obesity Symposium
Becetti, I., Bwenyi, E. L., de Araujo, I. E., Ard, J., Cryan, J. F., Farooqi, I. S., Ferrario, C. R., Gluck, M. E., Holsen, L. M., Kenny, P. J., Lawson, E. A., Lowell, B. B., Schur, E. A., Stanley, T. L., Tavakkoli, A., Grinspoon, S. K. & Singhal, V., Jul 2023, In: American Journal of Clinical Nutrition. 118, 1, p. 314-328 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
Control of fear by discrete prefrontal GABAergic populations encoding valence-specific information
Cummings, K. A., Bayshtok, S., Dong, T. N., Kenny, P. J. & Clem, R. L., 21 Sep 2022, In: Neuron. 110, 18, p. 3036-3052.e5
Research output: Contribution to journal › Article › peer-review

Open Access
31 Scopus citations
Hedgehog-interacting protein acts in the habenula to regulate nicotine intake
Caligiuri, S. P. B., Howe, W. M., Wills, L., Smith, A. C. W., Lei, Y., Bali, P., Heyer, M. P., Moen, J. K., Ables, J. L., Elayouby, K. S., Williams, M., Fillinger, C., Oketokoun, Z., Lehmann, V. E., DiFeliceantonio, A. G., Johnson, P. M., Beaumont, K., Sebra, R. P., Ibanez-Tallon, I. & Kenny, P. J., 15 Nov 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 46, e2209870119.
Research output: Contribution to journal › Article › peer-review

Open Access
4 Scopus citations
Neurobiological Mechanisms of Nicotine Reward and Aversion
Wills, L., Ables, J. L., Braunscheidel, K. M., Caligiuri, S. P. B., Elayouby, K. S., Fillinger, C., Ishikawa, M., Moen, J. K. & Kenny, P. J., 2022, In: Pharmacological Reviews. 74, 1, p. 271-310 40 p.
Research output: Contribution to journal › Article › peer-review

Open Access
63 Scopus citations

Study Findings on Neuroscience Discussed by a Researcher at Rockefeller University (Precise 3D Localization of Intracerebral Implants Using a Simple Brain Clearing Method)
Kenny, P.
16/12/24
1 item of Media coverage
Press/Media
Scientists Uncover Hidden Mechanism Behind Opioid Addiction – Discovery Could Revolutionize Addiction Treatment
O'Connor, R., Kenny, P. & Sebra, R.
16/08/24
1 item of Media coverage
Press/Media
Good Moods Due to Opioids? Newly Discovered Brain Region Responsible
Kenny, P.
16/08/24
1 item of Media coverage
Press/Media
Hooked on a feeling: Opioids evoke positive feelings through a newly identified brain region
Kenny, P.
13/08/24
2 items of Media coverage
Press/Media
Opioids evoke positive feelings through a newly identified brain region
Kenny, P.
13/08/24
1 item of Media coverage
Press/Media
Data on Opioids Reported by a Researcher at Icahn School of Medicine at Mount Sinai (A master regulator of opioid reward in the ventral prefrontal cortex)
O'Connor, R., Kenny, P. & Sebra, R.
21/06/24
1 item of Media coverage
Press/Media
Weight Loss Drugs: Are They Really Magic?
Kenny, P.
13/06/24
3 items of Media coverage
Press/Media
Weight Loss Drugs: Are They Really Magic?
Kenny, P.
13/06/24
1 item of Media coverage
Press/Media
Psychiatry drugs finally have pharma’s attention. Can they keep it?
Kenny, P.
10/04/24
1 item of Media coverage
Press/Media
Psychiatry drugs finally have pharma’s attention. Can they keep it?
Kenny, P.
8/04/24
1 item of Media coverage
Press/Media
Nondrug DIY Treatments for Depression
O'Connor, R.
16/12/23
1 item of Media coverage
Press/Media
Exercise Helps Pro Basketball Player Chris Wright Manage His Multiple Sclerosis
O'Connor, R. & Fabian, M.
7/12/23
1 item of Media coverage
Press/Media

Mount Sinai Drug Discovery Institute

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Purva Bali

Robert DeVita

Masago Ishikawa

Paul Kenny

Hasib Salah-Uddin

A master regulator of opioid reward in the ventral prefrontal cortex

Generative artificial intelligence-enabled dynamic detection of rat nicotine-related circuits

Hypothalamic CRF neurons facilitate brain reward function

Precise 3D Localization of Intracerebral Implants Using a Simple Brain Clearing Method

SR9883 is a novel small-molecule enhancer of α4β2* nicotinic acetylcholine receptor signaling that decreases intravenous nicotine self-administration in rats

The single-cell opioid responses in the context of HIV (SCORCH) consortium

Central and peripheral actions of nicotine that influence blood glucose homeostasis and the development of diabetes

New medications development for smoking cessation

The Neurobiology of Eating Behavior in Obesity: Mechanisms and Therapeutic Targets: A Report from the 23rd Annual Harvard Nutrition Obesity Symposium

Control of fear by discrete prefrontal GABAergic populations encoding valence-specific information

Hedgehog-interacting protein acts in the habenula to regulate nicotine intake

Neurobiological Mechanisms of Nicotine Reward and Aversion

Study Findings on Neuroscience Discussed by a Researcher at Rockefeller University (Precise 3D Localization of Intracerebral Implants Using a Simple Brain Clearing Method)

Scientists Uncover Hidden Mechanism Behind Opioid Addiction – Discovery Could Revolutionize Addiction Treatment

Good Moods Due to Opioids? Newly Discovered Brain Region Responsible

Hooked on a feeling: Opioids evoke positive feelings through a newly identified brain region

Opioids evoke positive feelings through a newly identified brain region

Data on Opioids Reported by a Researcher at Icahn School of Medicine at Mount Sinai (A master regulator of opioid reward in the ventral prefrontal cortex)

Weight Loss Drugs: Are They Really Magic?

Weight Loss Drugs: Are They Really Magic?

Psychiatry drugs finally have pharma’s attention. Can they keep it?

Psychiatry drugs finally have pharma’s attention. Can they keep it?

Nondrug DIY Treatments for Depression

Exercise Helps Pro Basketball Player Chris Wright Manage His Multiple Sclerosis

Mount Sinai Drug Discovery Institute

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Press/Media