Research output per year
Research output per year
Research output
- 1 - 50 out of 226 results
Search results
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2023
Genome-wide methylomic regulation of multiscale gene networks in Alzheimer's disease
Wang, E., Wang, M., Guo, L., Fullard, J. F., Micallef, C., Bendl, J., Song, W. M., Ming, C., Huang, Y., Li, Y., Yu, K., Peng, J., Bennett, D. A., De Jager, P. L., Roussos, P., Haroutunian, V. & Zhang, B., 2023, (Accepted/In press) In: Alzheimer's and Dementia.Research output: Contribution to journal › Article › peer-review
Open Access -
Multi-omics-based analysis of high grade serous ovarian cancer subtypes reveals distinct molecular processes linked to patient prognosis
Wang, Y. A., Neff, R., Song, W. M., Zhou, X., Vatansever, S., Walsh, M. J., Chen, S. H. & Zhang, B., 2023, (Accepted/In press) In: FEBS Open Bio.Research output: Contribution to journal › Article › peer-review
Open Access -
Pseudo-temporal dynamics of chemoresistant triple negative breast cancer cells reveal EGFR/HER2 inhibition as synthetic lethal during mid-neoadjuvant chemotherapy
Song, W. M., Chia, P. L., Zhou, X., Walsh, M., Silva, J. & Zhang, B., 17 Feb 2023, In: iScience. 26, 2, 106064.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Biopsy and blood-based molecular biomarker of inflammation in IBD
Argmann, C., Hou, R., Ungaro, R. C., Irizar, H., Al-Taie, Z., Huang, R., Kosoy, R., Venkat, S., Song, W. M., Di'narzo, A. F., Losic, B., Hao, K., Peters, L., Comella, P. H., Wei, G., Atreja, A., Mahajan, M., Iuga, A., Desai, P. T., Branigan, P., & 15 others, 2022, (Accepted/In press) In: Gut. 326451.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Changes in polyphenol serum levels and cognitive performance after dietary supplementation with Concord grape juice in veterans with Gulf War Illness
Van Doren, W. W., Iqbal, U. H., Helmer, D. A., Litke, D. R., Simon, J. E., Wu, Q., Zhao, D., Yin, Z., Ho, L., Osinubi, O. & Pasinetti, G. M., 1 Mar 2022, In: Life Sciences. 292, 119797.Research output: Contribution to journal › Article › peer-review
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Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
TCW, J., Qian, L., Pipalia, N. H., Chao, M. J., Liang, S. A., Shi, Y., Jain, B. R., Bertelsen, S. E., Kapoor, M., Marcora, E., Sikora, E., Andrews, E. J., Martini, A. C., Karch, C. M., Head, E., Holtzman, D. M., Zhang, B., Wang, M., Maxfield, F. R., Poon, W. W., & 1 others, 23 Jun 2022, In: Cell. 185, 13, p. 2213-2233.e25Research output: Contribution to journal › Article › peer-review
30 Scopus citations -
Chronic Intermittent Hypoxia Enhances Pathological Tau Seeding, Propagation, and Accumulation and Exacerbates Alzheimer-like Memory and Synaptic Plasticity Deficits and Molecular Signatures
Kazim, S. F., Sharma, A., Saroja, S. R., Seo, J. H., Larson, C. S., Ramakrishnan, A., Wang, M., Blitzer, R. D., Shen, L., Peña, C. J., Crary, J. F., Shimoda, L. A., Zhang, B., Nestler, E. J. & Pereira, A. C., 15 Feb 2022, In: Biological Psychiatry. 91, 4, p. 346-358 13 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Common and species-specific molecular signatures, networks, and regulators of influenza virus infection in mice, ferrets, and humans
Forst, C. V., Martin-Sancho, L., Tripathi, S., Wang, G., Dos Anjos Borges, L. G., Wang, M., Geber, A., Lashua, L., Ding, T., Zhou, X., Carter, C. E., Metreveli, G., Rodriguez-Frandsen, A., Urbanowski, M. D., White, K. M., Stein, D. A., Moulton, H., Chanda, S. K., Pache, L., Shaw, M. L., & 4 others, Oct 2022, In: Science advances. 8, 40, eabm5859.Research output: Contribution to journal › Article › peer-review
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Crystallin Mu in Medial Amygdala Mediates the Effect of Social Experience on Cocaine Seeking in Males but Not in Females
Walker, D. M., Zhou, X., Cunningham, A. M., Ramakrishnan, A., Cates, H. M., Lardner, C. K., Peña, C. J., Bagot, R. C., Issler, O., Van der Zee, Y., Lipschultz, A. P., Godino, A., Browne, C. J., Hodes, G. E., Parise, E. M., Torres-Berrio, A., Kennedy, P. J., Shen, L., Zhang, B. & Nestler, E. J., 1 Dec 2022, In: Biological Psychiatry. 92, 11, p. 895-906 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Culture shock: microglial heterogeneity, activation, and disrupted single-cell microglial networks in vitro
Cadiz, M. P., Jensen, T. D., Sens, J. P., Zhu, K., Song, W. M., Zhang, B., Ebbert, M., Chang, R. & Fryer, J. D., Dec 2022, In: Molecular Neurodegeneration. 17, 1, 26.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces β-Amyloid Load in Males and Females
Pan, A. L., Audrain, M., Sakakibara, E., Joshi, R., Zhu, X., Wang, Q., Wang, M., Beckmann, N. D., Schadt, E. E., Gandy, S., Zhang, B., Ehrlich, M. E. & Salton, S. R., Dec 2022, In: Cells. 11, 23, 3880.Research output: Contribution to journal › Article › peer-review
Open Access -
Dynamic plasticity of prostate cancer intermediate cells during androgen receptor-targeted therapy
Sandhu, H. S., Portman, K. L., Zhou, X., Zhao, J., Rialdi, A., Sfakianos, J. P., Guccione, E., Kyprianou, N., Zhang, B. & Mulholland, D. J., 26 Jul 2022, In: Cell Reports. 40, 4, 111123.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models
Cai, C. Z., Zhuang, X. X., Zhu, Q., Wu, M. Y., Su, H., Wang, X. J., Iyaswamy, A., Yue, Z., Wang, Q., Zhang, B., Xue, Y., Tan, J., Li, M., He, H. & Lu, J. H., 2022, In: Theranostics. 12, 4, p. 1738-1755 18 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Integrative metabolomics-genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease
for the Alzheimer's Disease Neuroimaging Initiative (ADNI) & the Alzheimer Disease Metabolomics Consortium, Jun 2022, In: Alzheimer's and Dementia. 18, 6, p. 1260-1278 19 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice
Lyons, C. E., Zhou, X., Razzoli, M., Chen, M., Xia, W., Ashe, K., Zhang, B. & Bartolomucci, A., May 2022, In: European Journal of Neuroscience. 55, 9-10, p. 2971-2985 15 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Microglial INPP5D limits plaque formation and glial reactivity in the PSAPP mouse model of Alzheimer's disease
Castranio, E. L., Hasel, P., Haure-Mirande, J. V., Ramirez Jimenez, A. V., Hamilton, B. W., Kim, R. D., Glabe, C. G., Wang, M., Zhang, B., Gandy, S., Liddelow, S. A. & Ehrlich, M. E., 2022, (Accepted/In press) In: Alzheimer's and Dementia.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Modeling COVID-19 dynamic using a two-strain model with vaccination
de León, U. A. P., Avila-Vales, E. & Huang, K. L., Apr 2022, In: Chaos, Solitons and Fractals. 157, 111927.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Modeling the Transmission of the SARS-CoV-2 Delta Variant in a Partially Vaccinated Population
de León, U. A. P., Avila-Vales, E. & Huang, K., Jan 2022, In: Viruses. 14, 1, 158.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Multiethnic Investigation of Risk and Immune Determinants of COVID-19 Outcomes
Jun, T., Mathew, D., Sharma, N., Nirenberg, S., Huang, H. H., Kovatch, P., Wherry, E. J. & Huang, K. L., 22 Jul 2022, In: Frontiers in Cellular and Infection Microbiology. 12, 933190.Research output: Contribution to journal › Article › peer-review
Open Access -
Numb is required for optimal contraction of skeletal muscle
De Gasperi, R., Mo, C., Azulai, D., Wang, Z., Harlow, L. M., Du, Y., Graham, Z., Pan, J., Liu, X. H., Guo, L., Zhang, B., Ko, F., Raczkowski, A. M., Bauman, W. A., Goulbourne, C. N., Zhao, W., Brotto, M. & Cardozo, C. P., Feb 2022, In: Journal of Cachexia, Sarcopenia and Muscle. 13, 1, p. 454-466 13 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination
Wang, N., Wang, M., Jeevaratnam, S., Rosenberg, C., Ikezu, T. C., Shue, F., Doss, S. V., Alnobani, A., Martens, Y. A., Wren, M., Asmann, Y. W., Zhang, B., Bu, G. & Liu, C. C., Dec 2022, In: Molecular Neurodegeneration. 17, 1, 75.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Peripheral and cognitive benefits of physical exercise in a mouse model of midlife metabolic syndrome
El Gaamouch, F., Lin, H. Y., Wang, Q., Zhao, W., Pan, J., Liu, K., Wong, J., Wu, C., Yuan, C., Cheng, H., Qin, W., Hao, K., Zhang, B. & Wang, J., Dec 2022, In: Scientific Reports. 12, 1, 3260.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Proteomic Analyses Identify Therapeutic Targets in Hepatocellular Carcinoma
Elmas, A., Lujambio, A. & Huang, K. L., 30 Mar 2022, In: Frontiers in Oncology. 12, 814120.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Sex disparities in influenza: A multiscale network analysis
Wang, C., Lashua, L. P., Carter, C. E., Johnson, S. K., Wang, M., Ross, T. M., Ghedin, E., Zhang, B. & Forst, C. V., 20 May 2022, In: iScience. 25, 5, 104192.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Sex-Specific Transcriptional Changes in Response to Adolescent Social Stress in the Brain's Reward Circuitry
Walker, D. M., Zhou, X., Cunningham, A. M., Lipschultz, A. P., Ramakrishnan, A., Cates, H. M., Bagot, R. C., Shen, L., Zhang, B. & Nestler, E. J., 1 Jan 2022, In: Biological Psychiatry. 91, 1, p. 118-128 11 p.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
Xu, P., Wang, M., Song, W. M., Wang, Q., Yuan, G. C., Sudmant, P. H., Zare, H., Tu, Z., Orr, M. E. & Zhang, B., Dec 2022, In: Molecular Neurodegeneration. 17, 1, 5.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Whole genome sequencing–based copy number variations reveal novel pathways and targets in Alzheimer's disease
Ming, C., Wang, M., Wang, Q., Neff, R., Wang, E., Shen, Q., Reddy, J. S., Wang, X., Allen, M., Ertekin-Taner, N., De Jager, P. L., Bennett, D. A., Haroutunian, V., Schadt, E. & Zhang, B., Oct 2022, In: Alzheimer's and Dementia. 18, 10, p. 1846-1867 22 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2021
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation
Sayed, F. A., Kodama, L., Fan, L., Carling, G. K., Udeochu, J. C., Le, D., Li, Q., Zhou, L., Ying Wong, M., Horowitz, R., Ye, P., Mathys, H., Wang, M., Niu, X., Mazutis, L., Jiang, X., Wang, X., Gao, F., Brendel, M., Telpoukhovskaia, M., & 20 others, 1 Dec 2021, In: Science Translational Medicine. 13, 622, abe3947.Research output: Contribution to journal › Article › peer-review
16 Scopus citations -
AeQTL: eQTL analysis using region-based aggregation of rare genomic variants
Dong, G., Wendl, M. C., Zhang, B., Ding, L. & Huang, K. L., 2021, In: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 26, p. 172-183 12 p.Research output: Contribution to journal › Article › peer-review
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Analytical protocol to identify local ancestry-associated molecular features in cancer
Cancer Genome Atlas Analysis Network, 17 Dec 2021, In: STAR Protocols. 2, 4, 100766.Research output: Contribution to journal › Article › peer-review
Open Access -
Association of neurogranin gene expression with Alzheimer's disease pathology in the perirhinal cortex
Sun, X., Wang, Q., Blennow, K., Zetterberg, H., McCarthy, M., Loewenstein, D. A., Vontell, R., Yue, Z. & Zhang, B., 2021, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 7, 1, e12162.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Atlas of RNA editing events affecting protein expression in aged and Alzheimer’s disease human brain tissue
Ma, Y., Dammer, E. B., Felsky, D., Duong, D. M., Klein, H. U., White, C. C., Zhou, M., Logsdon, B. A., McCabe, C., Xu, J., Wang, M., Wingo, T. S., Lah, J. J., Zhang, B., Schneider, J., Allen, M., Wang, X., Ertekin-Taner, N., Seyfried, N. T., Levey, A. I., & 2 others, Dec 2021, In: Nature Communications. 12, 1, 7035.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Deep Analysis of the Peripheral Immune System in IBD Reveals New Insight in Disease Subtyping and Response to Monotherapy or Combination Therapy
Kosoy, R., Kim-Schulze, S., Rahman, A., Friedman, J. R., Huang, R., Peters, L. A., Amir, E. A., Perrigoue, J., Stojmirovic, A., Song, W. M., Ke, H., Ungaro, R., Mehandru, S., Cho, J., Dubinsky, M., Curran, M., Brodmerkel, C., Schadt, E. E., Sands, B. E., Colombel, J. F., & 3 others, Jan 2021, In: Cellular and Molecular Gastroenterology and Hepatology. 12, 2, p. 599-632 34 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Diverse immune response of DNA damage repair-deficient tumors
Qing, T., Jun, T., Lindblad, K. E., Lujambio, A., Marczyk, M., Pusztai, L. & Huang, K. L., 18 May 2021, In: Cell Reports Medicine. 2, 5, 100276.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity
Wahane, S., Zhou, X., Zhou, X., Guo, L., Friedl, M. S., Kluge, M., Ramakrishnan, A., Shen, L., Friedel, C. C., Zhang, B., Friedel, R. H. & Zou, H., 24 Feb 2021, In: Science advances. 7, 9, eabd8811.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Genetic dependency of Alzheimer’s disease-associated genes across cells and tissue types
Jaladanki, S. K., Elmas, A., Malave, G. S. & Huang, K. L., Dec 2021, In: Scientific Reports. 11, 1, 12107.Research output: Contribution to journal › Article › peer-review
Open Access -
Genomic and molecular features distinguish young adult cancer from later-onset cancer
Lee, W., Wang, Z., Saffern, M., Jun, T. & Huang, K. L., 16 Nov 2021, In: Cell Reports. 37, 7, 110005.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Genomic determinants of homologous recombination deficiency across human cancers
Qing, T., Wang, X., Jun, T., Ding, L., Pusztai, L. & Huang, K. L., Sep 2021, In: Cancers. 13, 18, 4572.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
MicroRNA-195 rescues AD-associated lysosomal defects
Cao, J., Huang, M., Guo, L., Zhu, L., Hou, J., Zhang, L., Pero, A., Ng, S., Gaamouch, F. E., Elder, G., Sano, M., Goate, A., Tcw, J., Haroutunian, V., Zhang, B. & Cai, D., Sep 2021, In: Molecular Psychiatry. 26, 9, p. 4563 1 p.Research output: Contribution to journal › Article › peer-review
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MicroRNA-195 rescues ApoE4-induced cognitive deficits and lysosomal defects in Alzheimer’s disease pathogenesis
Cao, J., Huang, M., Guo, L., Zhu, L., Hou, J., Zhang, L., Pero, A., Ng, S., El Gaamouch, F., Elder, G., Sano, M., Goate, A., Tcw, J., Haroutunian, V., Zhang, B. & Cai, D., Sep 2021, In: Molecular Psychiatry. 26, 9, p. 4687-4701 15 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets
Neff, R. A., Wang, M., Vatansever, S., Guo, L., Ming, C., Wang, Q., Wang, E., Horgusluoglu-Moloch, E., Song, W. M., Li, A., Castranio, E. L., Julia, T. C. W., Ho, L., Goate, A., Fossati, V., Noggle, S., Gandy, S., Ehrlich, M. E., Katsel, P., Schadt, E., & 4 others, 6 Jan 2021, In: Science advances. 7, 2, eabb5398.Research output: Contribution to journal › Article › peer-review
Open Access54 Scopus citations -
Network models of primary melanoma microenvironments identify key melanoma regulators underlying prognosis
Song, W. M., Agrawal, P., Von Itter, R., Fontanals-Cirera, B., Wang, M., Zhou, X., Mahal, L. K., Hernando, E. & Zhang, B., 1 Dec 2021, In: Nature Communications. 12, 1, 1214.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Non-cancer-related pathogenic germline variants and expression consequences in ten-thousand cancer genomes
Wang, Z., Fan, X., Shen, Y., Pagadala, M. S., Signer, R., Cygan, K. J., Fairbrother, W. G., Carter, H., Chung, W. K. & Huang, K. L., Dec 2021, In: Genome Medicine. 13, 1, 147.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Pan-cancer proteogenomic investigations identify post-transcriptional kinase targets
Elmas, A., Tharakan, S., Jaladanki, S., Galsky, M. D., Liu, T. & Huang, K. L., Dec 2021, In: Communications Biology. 4, 1, 1112.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Phenome-wide and expression quantitative trait locus associations of coronavirus disease 2019 genetic risk loci
Moon, C. Y., Schilder, B. M., Raj, T. & Huang, K. L., 25 Jun 2021, In: iScience. 24, 6, 102550.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Prediction of individual COVID-19 diagnosis using baseline demographics and lab data
Zhang, J., Jun, T., Frank, J., Nirenberg, S., Kovatch, P. & Huang, K. L., Dec 2021, In: Scientific Reports. 11, 1, 13913.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Profiling senescent cells in human brains reveals neurons with CDKN2D/p19 and tau neuropathology
Dehkordi, S. K., Walker, J., Sah, E., Bennett, E., Atrian, F., Frost, B., Woost, B., Bennett, R. E., Orr, T. C., Zhou, Y., Andhey, P. S., Colonna, M., Sudmant, P. H., Xu, P., Wang, M., Zhang, B., Zare, H. & Orr, M. E., Dec 2021, In: Nature Aging. 1, 12, p. 1107-1116 10 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Prosaposin mediates inflammation in atherosclerosis
van Leent, M. M. T., Beldman, T. J., Toner, Y. C., Lameijer, M. A., Rother, N., Bekkering, S., Teunissen, A. J. P., Zhou, X., van der Meel, R., Malkus, J., Nauta, S. A., Klein, E. D., Fay, F., Sanchez-Gaytan, B. L., Pérez-Medina, C., Kluza, E., Ye, Y. X., Wojtkiewicz, G., Fisher, E. A., Swirski, F. K., & 13 others, 10 Mar 2021, In: Science Translational Medicine. 13, 584, eabe1433.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Reactive or transgenic increase in microglial TYROBP reveals a TREM2-independent TYROBP–APOE link in wild-type and Alzheimer's-related mice
Audrain, M., Haure-Mirande, J. V., Mleczko, J., Wang, M., Griffin, J. K., St George-Hyslop, P. H., Fraser, P., Zhang, B., Gandy, S. & Ehrlich, M. E., Feb 2021, In: Alzheimer's and Dementia. 17, 2, p. 149-163 15 p.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
Selective linkage of mitochondrial enzymes to intracellular calcium stores differs between human-induced pluripotent stem cells, neural stem cells, and neurons
Chen, H., Cross, A. C., Thakkar, A., Xu, H., Li, A., Paull, D., Noggle, S. A., Kruger, L., Denton, T. T. & Gibson, G. E., Mar 2021, In: Journal of Neurochemistry. 156, 6, p. 867-879 13 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations