Mount Sinai Center for Transformative Disease Modeling

Icahn School of Medicine at Mount Sinai

3 Finished
4 Active

Dissect regulation of glial nets surrounding amyloid plaques in Alzheimer's disease
Friedel, R., Wang, M. & Zou, H.
National Institute on Aging
5/05/22 → 30/04/25
Project: Research
Systematic dissection of novel Alzheimer's genes in microglia
Wang, M.
Alzheimer's Association
1/01/22 → …
Project: Research
Systems modeling of shared and distinct molecular mechanisms underlying comorbid Major Depressive Disorder and Alzheimer's disease
Salton, S., Ehrlich, M., Ehrlich, M. E., Ehrlich, M. M. E., Salton, S. R. & Zhang, B.
National Institute on Aging
30/09/18 → 30/04/23
Project: Research
Characterizing the Influence of Immune Inflammatory Activities in the Clinical Progression of Alzheimer's Disease Dementia
Ho, L.
American Federation for Aging Research
1/01/02 → …
Project: Research
Characterization of protective roles of ApoE2 against aging and Alzheimer's disease
Cai, D., LaDu, M. J. & Zhang, B.
National Institute on Aging
15/09/19 → 31/08/21
Project: Research
Identification and characterization of AD risk networks using multi-dimensional omics data
Goate, A., Cruchaga, C. & Zhang, B.
National Institute on Aging
15/07/16 → 31/05/21
Project: Research
Pasinetti: Overall; Dietary Botanicals in the Preservation of Cognitive and Psychological Resilience (Pasinetti)
Pasinetti, G., Dixon, R. A., Faith, J., Ho, L., Russo, S. & Wang, J.
National Center for Complementary and Integrative Health
1/09/15 → 30/06/21
Project: Research

14951 Citations
64 h-index
222 Article
24 Comment/debate
22 Review article
8 Chapter
More

Author Correction: Inferring structural variant cancer cell fraction (Nature Communications, (2020), 11, 1, (730), 10.1038/s41467-020-14351-8)
PCAWG Evolution and Heterogeneity Working Group & PCAWG Consortium, Dec 2022, In: Nature Communications. 13, 1, 7568.
Research output: Contribution to journal › Comment/debate

Open Access
Author Correction: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig (Nature Communications, (2020), 11, 1, (731), 10.1038/s41467-020-14352-7)
PCAWG Evolution and Heterogeneity Working Group & PCAWG Consortium, Dec 2022, In: Nature Communications. 13, 1, 7567.
Research output: Contribution to journal › Comment/debate

Open Access
Author Correction: Integrative pathway enrichment analysis of multivariate omics data (Nature Communications, (2020), 11, 1, (735), 10.1038/s41467-019-13983-9)
PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 2022, In: Nature Communications. 13, 1, 7570.
Research output: Contribution to journal › Comment/debate

Open Access
Author Correction: High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations (Nature Communications, (2020), 11, 1, (736), 10.1038/s41467-019-13885-w)
PCAWG Transcriptome Working Group, PCAWG Structural Variation Working Group & PCAWG Consortium, Dec 2022, In: Nature Communications. 13, 1, 7572.
Research output: Contribution to journal › Comment/debate

Open Access
Author Correction: Combined burden and functional impact tests for cancer driver discovery using DriverPower (Nature Communications, (2020), 11, 1, (734), 10.1038/s41467-019-13929-1)
PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 2022, In: Nature Communications. 13, 1, 7571.
Research output: Contribution to journal › Comment/debate

Open Access
Author Correction: Pathway and network analysis of more than 2500 whole cancer genomes (Nature Communications, (2020), 11, 1, (729), 10.1038/s41467-020-14367-0)
PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 2022, In: Nature Communications. 13, 1, 7566.
Research output: Contribution to journal › Comment/debate

Open Access
Author Correction: A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns (Nature Communications, (2020), 11, 1, (728), 10.1038/s41467-019-13825-8)
PCAWG Tumor Subtypes and Clinical Translation Working Group & PCAWG Consortium, Dec 2022, In: Nature Communications. 13, 1, 7573.
Research output: Contribution to journal › Comment/debate

Open Access
Author Correction: Genomic footprints of activated telomere maintenance mechanisms in cancer (Nature Communications, (2020), 11, 1, (733), 10.1038/s41467-019-13824-9)
PCAWG-Structural Variation Working Group & PCAWG Consortium, Dec 2022, In: Nature Communications. 13, 1, 7574.
Research output: Contribution to journal › Comment/debate

Open Access
Benefits of dietary polyphenols in Alzheimer’s disease
El Gaamouch, F., Chen, F., Ho, L., Lin, H. Y., Yuan, C., Wong, J. & Wang, J., 13 Dec 2022, In: Frontiers in Aging Neuroscience. 14, 1019942.
Research output: Contribution to journal › Short survey › peer-review

Open Access
Biopsy and blood-based molecular biomarker of inflammation in IBD
Argmann, C., Hou, R., Ungaro, R. C., Irizar, H., Al-Taie, Z., Huang, R., Kosoy, R., Venkat, S., Song, W. M., Di'narzo, A. F., Losic, B., Hao, K., Peters, L., Comella, P. H., Wei, G., Atreja, A., Mahajan, M., Iuga, A., Desai, P. T., Branigan, P., & 15 othersStojmirovic, A., Perrigoue, J., Brodmerkel, C., Curran, M., Friedman, J. R., Hart, A., Lamousé-Smith, E., Wehkamp, J., Mehandru, S., Schadt, E. E., Sands, B. E., Dubinsky, M. C., Colombel, J. F., Kasarskis, A. & Suárez-Fariñas, M., 2022, (Accepted/In press) In: Gut. 326451.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Changes in polyphenol serum levels and cognitive performance after dietary supplementation with Concord grape juice in veterans with Gulf War Illness
Van Doren, W. W., Iqbal, U. H., Helmer, D. A., Litke, D. R., Simon, J. E., Wu, Q., Zhao, D., Yin, Z., Ho, L., Osinubi, O. & Pasinetti, G. M., 1 Mar 2022, In: Life Sciences. 292, 119797.
Research output: Contribution to journal › Article › peer-review
Cholesterol and matrisome pathways dysregulated in astrocytes and microglia
TCW, J., Qian, L., Pipalia, N. H., Chao, M. J., Liang, S. A., Shi, Y., Jain, B. R., Bertelsen, S. E., Kapoor, M., Marcora, E., Sikora, E., Andrews, E. J., Martini, A. C., Karch, C. M., Head, E., Holtzman, D. M., Zhang, B., Wang, M., Maxfield, F. R., Poon, W. W., & 1 othersGoate, A. M., 23 Jun 2022, In: Cell. 185, 13, p. 2213-2233.e25
Research output: Contribution to journal › Article › peer-review
26 Scopus citations

Researchers from Tsinghua University Report on Findings in Chemicals and Chemistry (Realizing Metastable Cobaltite Perovskite Via Proton-induced Filling of Oxygen Vacancy Channels)
Qian Wang
26/01/23
1 item of Media coverage
Press/Media
Findings from Beijing Institute of Technology Reveals New Findings on Tribology (Effects of Operating Conditions On the Tribological Behavior of a Wet Multi-disc Clutch During the Running-in Process)
Qian Wang
25/01/23
1 item of Media coverage
Press/Media
Research Results from Affiliated Yantai Yuhuangding Hospital of Qingdao University Update Understanding of Thymectomy (Robot-assisted thoracoscopic surgery vs. sternotomy for thymectomy: A systematic review and meta-analysis)
Qian Wang
24/01/23
1 item of Media coverage
Press/Media
Alarm Bells Ring for Great Hammerheads After Scientists Sequence the Genomes of Endangered Sharks
Minghui Wang
23/01/23
2 items of Media coverage
Press/Media
New Findings Reported from Icahn School of Medicine at Mount Sinai Describe Advances in Alzheimer Disease [Dual-specificity Protein Phosphatase 4 (Dusp4) Overexpression Improves Learning Behavior Selectively In Female 5xfad Mice, and Reduces ...]
Noam Beckmann, Mickael Audrain, Qian Wang, Eric Schadt, Minghui Wang, Michelle Ehrlich, Samuel Gandy & Rajeev Joshi
16/01/23
1 item of Media coverage
Press/Media
New Nanosheets Data Have Been Reported by Investigators at Tsinghua University [Interfacial Polarization Suppression of P(Vdf-hfp) Film Through 2d Montmorillonite Nanosheets Coating]
Qian Wang
11/01/23
1 item of Media coverage
Press/Media
Researchers from Chinese Academy of Sciences Detail Findings in Chemicals and Chemistry (In-situ Production of Iron Flocculation and Reactive Oxygen Species By Electrochemically Decomposing Siderite: an Innovative Fe-ec Route To Remove ...)
Qian Wang
10/01/23
1 item of Media coverage
Press/Media
Data on Photoinhibition Discussed by Researchers at Chinese Academy of Sciences (Photoinhibition of Photosystem I Induced by Different Intensities of Fluctuating Light Is Determined by the Kinetics of pH Formation Rather Than Linear Electron ...)
Qian Wang
10/01/23
1 item of Media coverage
Press/Media
State Intellectual Property Office of China Receives Electric Power Science Res Institute of Liaoning Province Electric Power, Beijing Double Bayesian Intelligent Safety Science and Tech Limited, Univ Northeast and Shenyang Automation Res Institute of Chi
Qian Wang
7/01/23
1 item of Media coverage
Press/Media
Findings from Tsinghua University in the Area of Nanoscience and Nanotechnology Reported (Spin Selectivity In Chiral Hybrid Cobalt Halide Films With Ultrasmooth Surface)
Qian Wang
2/01/23
1 item of Media coverage
Press/Media
Investigators from Tsinghua University Report New Data on Nanocoatings (Improving Surface Performance of Silicone Rubber for Composite Insulators By Multifunctional Nano-coating)
Qian Wang
2/01/23
1 item of Media coverage
Press/Media
Icahn School of Medicine at Mount Sinai Researchers Broaden Understanding of Alzheimer Disease [Dual-Specificity Protein Phosphatase 4 (DUSP4) Overexpression Improves Learning Behavior Selectively in Female 5xFAD Mice, and Reduces b-Amyloid Load ...]
Noam Beckmann, Mickael Audrain, Qian Wang, Eric Schadt, Minghui Wang, Michelle Ehrlich, Samuel Gandy & Rajeev Joshi
27/12/22
1 item of Media coverage
Press/Media

Mount Sinai Center for Transformative Disease Modeling

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