Projects per year
Organization profile
organization profile
The Mount Sinai Center for Bioinformatics develops analytic methods to help experimental biologists to study the increasingly diverse and complex data that are collected from human cells, tissues, and patients. Our Center builds on many of the strengths of the Icahn School of Medicine at Mount Sinai. The Medical School has strong departments in basic science research and clinical care, and we aim to strengthen between these departments.
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Dive into the research topics where Mount Sinai Center for Bioinformatics is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
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Elucidating the Molecular Mechanisms that Mediate DKD Progression in Patients Living with HIV
He, J. J. C. & Ma’ayan, A.
National Institute of Diabetes and Digestive and Kidney Diseases
1/12/21 → 30/11/23
Project: Research
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Illuminating the Druggable Genome Data Coordinating Center - Engagement Plan with the CFDE
Lambert, C. C. G., Ma’ayan, A., Ma'ayan, A. & Oprea, T. I.
23/09/20 → 22/09/22
Project: Research
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Integrative informatics approach to develop safe glucocorticoid therapies
Budunova, I., Dudley, J. & Ma’ayan, A.
National Institute of General Medical Sciences
15/08/15 → 30/04/21
Project: Research
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Role of HIPK2 in kidney fibrosis
National Institute of Diabetes and Digestive and Kidney Diseases
1/07/10 → 30/06/21
Project: Research
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ECC UNIT II
Ma'ayan, A. A. & Ma’ayan, A.
National Institute of General Medical Sciences
18/09/07 → 31/08/12
Project: Research
Research output
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Age alters the oncogenic trajectory toward luminal mammary tumors that activate unfolded proteins responses
Jenkins, E. C., Chattopadhyay, M., Gomez, M., Torre, D., Ma'ayan, A., Torres-Martin, M., Sia, D. & Germain, D., Oct 2022, In: Aging Cell. 21, 10, e13665.Research output: Contribution to journal › Article › peer-review
Open Access -
A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses
Gross, S. M., Dane, M. A., Smith, R. L., Devlin, K. L., McLean, I. C., Derrick, D. S., Mills, C. E., Subramanian, K., London, A. B., Torre, D., Evangelista, J. E., Clarke, D. J. B., Xie, Z., Erdem, C., Lyons, N., Natoli, T., Pessa, S., Lu, X., Mullahoo, J., Li, J., & 30 others, Dec 2022, In: Communications Biology. 5, 1, 1066.Research output: Contribution to journal › Article › peer-review
Open Access -
BlitzGSEA: efficient computation of gene set enrichment analysis through gamma distribution approximation
Lachmann, A., Xie, Z. & Ma'ayan, A., 15 Apr 2022, In: Bioinformatics. 38, 8, p. 2356-2357 2 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Connecting omics signatures and revealing biological mechanisms with iLINCS
Pilarczyk, M., Fazel-Najafabadi, M., Kouril, M., Shamsaei, B., Vasiliauskas, J., Niu, W., Mahi, N., Zhang, L., Clark, N. A., Ren, Y., White, S., Karim, R., Xu, H., Biesiada, J., Bennett, M. F., Davidson, S. E., Reichard, J. F., Roberts, K., Stathias, V., Koleti, A., & 6 others, Dec 2022, In: Nature Communications. 13, 1, 4678.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
DrugShot: querying biomedical search terms to retrieve prioritized lists of small molecules
Kropiwnicki, E., Lachmann, A., Clarke, D. J. B., Xie, Z., Jagodnik, K. M. & Ma’ayan, A., Dec 2022, In: BMC Bioinformatics. 23, 1, 76.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Gene and drug landing page aggregator
Clarke, D. J. B., Kuleshov, M. V., Xie, Z., Evangelista, J. E., Meyers, M. R., Kropiwnicki, E., Jenkins, S. L. & Ma'ayan, A., 2022, In: Bioinformatics Advances. 2, 1, vbac013.Research output: Contribution to journal › Article › peer-review
Open Access -
Gene set predictor for post-treatment Lyme disease
Clarke, D. J. B., Rebman, A. W., Fan, J., Soloski, M. J., Aucott, J. N. & Ma'ayan, A., 15 Nov 2022, In: Cell Reports Medicine. 3, 11, 100816.Research output: Contribution to journal › Article › peer-review
Open Access -
Getting Started with LINCS Datasets and Tools
Xie, Z., Kropiwnicki, E., Wojciechowicz, M. L., Jagodnik, K. M., Shu, I., Bailey, A., Clarke, D. J. B., Jeon, M., Evangelista, J. E., V. Kuleshov, M., Lachmann, A., Parigi, A. A., Sanchez, J. M., Jenkins, S. L. & Ma'ayan, A., Jul 2022, In: Current Protocols. 2, 7, e487.Research output: Contribution to journal › Article › peer-review
Open Access -
Getting Started with the IDG KMC Datasets and Tools
Kropiwnicki, E., Binder, J. L., Yang, J. J., Holmes, J., Lachmann, A., Clarke, D. J. B., Sheils, T., Kelleher, K. J., Metzger, V. T., Bologa, C. G., Oprea, T. I. & Ma'ayan, A., Jan 2022, In: Current Protocols. 2, 1, e355.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Making Common Fund data more findable: catalyzing a data ecosystem
Charbonneau, A. L., Brady, A., Czajkowski, K., Aluvathingal, J., Canchi, S., Carter, R., Chard, K., Clarke, D. J. B., Crabtree, J., Creasy, H. H., D'Arcy, M., Felix, V., Giglio, M., Gingrich, A., Harris, R. M., Hodges, T. K., Ifeonu, O., Jeon, M., Kropiwnicki, E., Lim, M. C. W., & 22 others, 2022, In: GigaScience. 11, giac105.Research output: Contribution to journal › Article › peer-review
Open Access -
PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes
Wickramasinghe, N. M., Sachs, D., Shewale, B., Gonzalez, D. M., Dhanan-Krishnan, P., Torre, D., LaMarca, E., Raimo, S., Dariolli, R., Serasinghe, M. N., Mayourian, J., Sebra, R., Beaumont, K., Iyengar, S., French, D. L., Hansen, A., Eschenhagen, T., Chipuk, J. E., Sobie, E. A., Jacobs, A., & 6 others, 7 Apr 2022, In: Cell Stem Cell. 29, 4, p. 559-576.e7Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
SigCom LINCS: data and metadata search engine for a million gene expression signatures
Evangelista, J. E., Clarke, D. J. B., Xie, Z., Lachmann, A., Jeon, M., Chen, K., Jagodnik, K. M., Jenkins, S. L., Kuleshov, M. V., Wojciechowicz, M. L., Schürer, S. C., Medvedovic, M. & Ma'ayan, A., 5 Jul 2022, In: Nucleic Acids Research. 50, W1, p. W697-W709Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations
Press/Media
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Studies in the Area of Lyme Disease Reported from Icahn School of Medicine at Mount Sinai (Gene Set Predictor for Post-treatment Lyme Disease)
25/01/23
1 item of Media coverage
Press/Media
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Genes to potentially diagnose long-term Lyme disease identified.
17/01/23
1 item of Media coverage
Press/Media
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Genes for Potential Long-Term Lyme Disease Diagnosis Identified
29/11/22
1 item of Media coverage
Press/Media
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Genes could be key to diagnosing Lyme disease, scientists say
28/11/22
1 item of Media coverage
Press/Media
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Genetic profiling of Lyme disease could bring new therapeutic targets
17/11/22
1 item of Media coverage
Press/Media
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Long-Term Risk of Breast Cancer after Diagnosis of Benign Breast Disease by Screening Mammography
17/11/22
1 item of Media coverage
Press/Media
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Scientists discover genes to diagnose long-term Lyme disease
16/11/22
6 items of Media coverage
Press/Media
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Gene Set Could Identify Patients With Post-Treatment Lyme Disease
16/11/22
1 item of Media coverage
Press/Media
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Genes to Potentially Diagnose Long-Term Lyme Disease Identified
14/11/22 → 16/11/22
70 items of Media coverage
Press/Media
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Genes to Potentially Diagnose Long-Term Lyme Disease Identified.
15/11/22
1 item of Media coverage
Press/Media
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Mount Sinai Health System: Genes to Potentially Diagnose Long-Term Lyme Disease Identified
15/11/22
1 item of Media coverage
Press/Media