Mount Sinai Center for Bioinformatics

Icahn School of Medicine at Mount Sinai

Organization profile

The Mount Sinai Center for Bioinformatics develops analytic methods to help experimental biologists to study the increasingly diverse and complex data that are collected from human cells, tissues, and patients. Our Center builds on many of the strengths of the Icahn School of Medicine at Mount Sinai. The Medical School has strong departments in basic science research and clinical care, and we aim to strengthen between these departments.

35888 Citations
70 h-index
180 Article
19 Review article
8 Short survey
7 Conference contribution
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Causal inference can lead us to modifiable mechanisms and informative archetypes in sepsis
Baillie, J. K., Angus, D., Burnham, K., Calandra, T., Calfee, C., Gutteridge, A., Hacohen, N., Khatri, P., Langley, R., Ma’ayan, A., Marshall, J., Maslove, D., Prescott, H. C., Rowan, K., Scicluna, B. P., Seymour, C., Shankar-Hari, M., Shapiro, N., Joost Wiersinga, W. & Singer, M. & 1 others, Randolph, A. G., Dec 2024, In: Intensive Care Medicine. 50, 12, p. 2031-2042 12 p.
Research output: Contribution to journal › Review article › peer-review
Comprehensive proteogenomic characterization of rare kidney tumors
Chinnaiyan, A. M., Cieslik, M., Dhanasekaran, S. M., Zhang, H., Nesvizhskii, A. I. & Clinical Proteomic Tumor Analysis Consortium, 21 May 2024, In: Cell Reports Medicine. 5, 5, 101547.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
Multiomics2Targets identifies targets from cancer cohorts profiled with transcriptomics, proteomics, and phosphoproteomics
Deng, E. Z., Marino, G. B., Clarke, D. J. B., Diamant, I., Resnick, A. C., Ma, W., Wang, P. & Ma'ayan, A., 19 Aug 2024, In: Cell Reports Methods. 4, 8, 100839.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Pan-cancer proteogenomics characterization of tumor immunity
Clinical Proteomic Tumor Analysis Consortium, 29 Feb 2024, In: Cell. 187, 5, p. 1255-1277.e27
Research output: Contribution to journal › Article › peer-review

Open Access
15 Scopus citations
Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy
Vinik, Y., Maimon, A., Dubey, V., Raj, H., Abramovitch, I., Malitsky, S., Itkin, M., Ma'ayan, A., Westermann, F., Gottlieb, E., Ruppin, E. & Lev, S., 8 May 2024, In: Advanced Science. 11, 17, 2307263.
Research output: Contribution to journal › Article › peer-review

Open Access
9 Scopus citations
Protocol for using Multiomics2Targets to identify targets and driver kinases for cancer cohorts profiled with multi-omics assays
Marino, G. B., Deng, E. Z., Clarke, D. J. B., Diamant, I., Resnick, A. C., Ma, W., Wang, P. & Ma'ayan, A., 20 Dec 2024, In: STAR Protocols. 5, 4, 103457.
Research output: Contribution to journal › Article › peer-review

Open Access
Regulatory elements in SEM1-DLX5-DLX6 (7q21.3) locus contribute to genetic control of coronal nonsyndromic craniosynostosis and bone density-related traits
Nicoletti, P., Zafer, S., Matok, L., Irron, I., Patrick, M., Haklai, R., Evangelista, J. E., Marino, G. B., Ma'ayan, A., Sewda, A., Holmes, G., Britton, S. R., Lee, W. J., Wu, M., Ru, Y., Arnaud, E., Botto, L., Brody, L. C., Byren, J. C. & Caggana, M. & 57 others, Carmichael, S. L., Cilliers, D., Conway, K., Crawford, K., Cuellar, A., Di Rocco, F., Engel, M., Fearon, J., Feldkamp, M. L., Finnell, R., Fisher, S., Freudlsperger, C., Garcia-Fructuoso, G., Hagge, R., Heuzé, Y., Harshbarger, R. J., Hobbs, C., Howley, M., Jenkins, M. M., Johnson, D., Justice, C. M., Kane, A., Kay, D., Gosain, A. K., Langlois, P., Legal-Mallet, L., Lin, A. E., Mills, J. L., Morton, J. E. V., Noons, P., Olshan, A., Persing, J., Phipps, J. M., Redett, R., Reefhuis, J., Rizk, E., Samson, T. D., Shaw, G. M., Sicko, R., Smith, N., Staffenberg, D., Stoler, J., Sweeney, E., Taub, P. J., Timberlake, A. T., Topczewska, J., Wall, S. A., Wilson, A. F., Wilson, L. C., Boyadjiev, S. A., Wilkie, A. O. M., Richtsmeier, J. T., Jabs, E. W., Romitti, P. A., Karasik, D., Birnbaum, R. Y. & Peter, I., Jan 2024, In: Genetics in Medicine Open. 2, 101851.
Research output: Contribution to journal › Article › peer-review

Open Access
Rummagene: massive mining of gene sets from supporting materials of biomedical research publications
Clarke, D. J. B., Marino, G. B., Deng, E. Z., Xie, Z., Evangelista, J. E. & Ma’ayan, A., Dec 2024, In: Communications Biology. 7, 1, 482.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
RummaGEO: Automatic mining of human and mouse gene sets from GEO
Marino, G. B., Clarke, D. J. B., Lachmann, A., Deng, E. Z. & Ma'ayan, A., 11 Oct 2024, In: Patterns. 5, 10, 101072.
Research output: Contribution to journal › Article › peer-review

Open Access
Computational screen to identify potential targets for immunotherapeutic identification and removal of senescence cells
Deng, E. Z., Fleishman, R. H., Xie, Z., Marino, G. B., Clarke, D. J. B. & Ma'ayan, A., Jun 2023, In: Aging Cell. 22, 6, e13809.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
D2H2: diabetes data and hypothesis hub
Marino, G. B., Ahmed, N., Xie, Z., Jagodnik, K. M., Han, J., Clarke, D. J. B., Lachmann, A., Keller, M. P., Attie, A. D. & Ma'Ayan, A., 2023, In: Bioinformatics Advances. 3, 1, vbad178.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
Dex-Benchmark: datasets and code to evaluate algorithms for transcriptomics data analysis
Xie, Z., Chen, C. & Ma’ayan, A., 2023, In: PeerJ. 11, e16351.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations

Increased autoreactivity and maturity of EBI2+ antibody-secreting cells from nasal polyps
Ma’ayan, A.
10/09/24
1 item of Media coverage
Press/Media
Researchers' from Icahn School of Medicine at Mount Sinai Report Details of New Studies and Findings in the Area of Genetics [Regulatory elements in SEM1-DLX5-DLX6 (7q21.3) locus contribute to genetic control of coronal nonsyndromic ...]
Nicoletti, P., Peter, I., Holmes, G. & Ma’ayan, A.
22/07/24
1 item of Media coverage
Press/Media
Findings from Icahn School of Medicine at Mount Sinai Reveals New Findings on Cancer (Pan-cancer Proteogenomics Characterization of Tumor Immunity)
Reva, B. A., Sebra, R., Wang, P., Song, X., Ma’ayan, A., Petralia, F. & Chowdhury, S.
4/06/24
1 item of Media coverage
Press/Media
New Findings from Icahn School of Medicine at Mount Sinai Describe Advances in Biology (Rummagene: massive mining of gene sets from supporting materials of biomedical research publications)
Ma’ayan, A.
6/05/24
1 item of Media coverage
Press/Media
Scientists analyze the immune environment in cancer
Wang, P., Ma’ayan, A. & Petralia, F.
16/02/24
1 item of Media coverage
Press/Media
Mount Sinai Health System: Researchers Characterize the Immune Landscape in Cancer
Wang, P., Ma’ayan, A. & Petralia, F.
14/02/24 → 15/02/24
2 items of Media coverage
Press/Media
Mount Sinai Hospital: Researchers Characterize the Immune Landscape in Cancer
Wang, P., Ma’ayan, A. & Petralia, F.
15/02/24
1 item of Media coverage
Press/Media
Researchers Characterize the Immune Landscape in Cancer
Wang, P., Ma’ayan, A. & Petralia, F.
14/02/24
6 items of Media coverage
Press/Media
NIH Award to Establish Data Integration Hub for Common Fund Programs
Nestler, E. J. & Ma’ayan, A.
17/10/23
1 item of Media coverage
Press/Media
Icahn School of Medicine at Mount Sinai, University of California San Diego Receive $8.5M Award to Establish a Data Integration Hub for NIH Common Fund Supported Programs
Nestler, E. J. & Ma’ayan, A.
13/10/23
1 item of Media coverage
Press/Media
Icahn School of Medicine at Mount Sinai and the University of California San Diego Receive $8.5 Million Award to Establish a Data Integration Hub for NIH Common Fund Supported Programs
Nestler, E. J. & Ma’ayan, A.
11/10/23
2 items of Media coverage
Press/Media
Icahn School of Medicine at Mount Sinai and the University of California San Diego Receive $8.5 Million NIH Award to Establish a Data Integration Hub
Nestler, E. J. & Ma’ayan, A.
11/10/23
17 items of Media coverage
Press/Media

Mount Sinai Center for Bioinformatics

Organization profile

Organization profile

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Alexander Lachmann

Avi Ma’ayan

Causal inference can lead us to modifiable mechanisms and informative archetypes in sepsis

Comprehensive proteogenomic characterization of rare kidney tumors

Multiomics2Targets identifies targets from cancer cohorts profiled with transcriptomics, proteomics, and phosphoproteomics

Pan-cancer proteogenomics characterization of tumor immunity

Programming a Ferroptosis-to-Apoptosis Transition Landscape Revealed Ferroptosis Biomarkers and Repressors for Cancer Therapy

Protocol for using Multiomics2Targets to identify targets and driver kinases for cancer cohorts profiled with multi-omics assays

Regulatory elements in SEM1-DLX5-DLX6 (7q21.3) locus contribute to genetic control of coronal nonsyndromic craniosynostosis and bone density-related traits

Rummagene: massive mining of gene sets from supporting materials of biomedical research publications

RummaGEO: Automatic mining of human and mouse gene sets from GEO

Computational screen to identify potential targets for immunotherapeutic identification and removal of senescence cells

D2H2: diabetes data and hypothesis hub

Dex-Benchmark: datasets and code to evaluate algorithms for transcriptomics data analysis

Increased autoreactivity and maturity of EBI2+ antibody-secreting cells from nasal polyps

Researchers' from Icahn School of Medicine at Mount Sinai Report Details of New Studies and Findings in the Area of Genetics [Regulatory elements in SEM1-DLX5-DLX6 (7q21.3) locus contribute to genetic control of coronal nonsyndromic ...]

Findings from Icahn School of Medicine at Mount Sinai Reveals New Findings on Cancer (Pan-cancer Proteogenomics Characterization of Tumor Immunity)

New Findings from Icahn School of Medicine at Mount Sinai Describe Advances in Biology (Rummagene: massive mining of gene sets from supporting materials of biomedical research publications)

Scientists analyze the immune environment in cancer

Mount Sinai Health System: Researchers Characterize the Immune Landscape in Cancer

Mount Sinai Hospital: Researchers Characterize the Immune Landscape in Cancer

Researchers Characterize the Immune Landscape in Cancer

NIH Award to Establish Data Integration Hub for Common Fund Programs

Icahn School of Medicine at Mount Sinai, University of California San Diego Receive $8.5M Award to Establish a Data Integration Hub for NIH Common Fund Supported Programs

Icahn School of Medicine at Mount Sinai and the University of California San Diego Receive $8.5 Million Award to Establish a Data Integration Hub for NIH Common Fund Supported Programs

Icahn School of Medicine at Mount Sinai and the University of California San Diego Receive $8.5 Million NIH Award to Establish a Data Integration Hub

Mount Sinai Center for Bioinformatics

Organization profile

Organization profile

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Press/Media