Medicine

Projects

Projects per year 1980 2004 2006 2007 2009 2010 2011 2012 2014 2015 2016 2017 2018 2019 2020 2026

• 320 Active
• 1425 Finished

Projects per year

Search results

• Finished

  Role of apoptosis in the intestinal epithelium during homeostasis and disease

  Blander, J.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/04/17 → 31/03/21

  Project: Research

  • intestinal mucosa 100%
  • inflammatory bowel disease 90%
  • apoptosis 88%
  • homeostasis 69%
  • phagocytes 59%

• Molecular and Metabolic phenotype of Impaired AdipoR1 in the Heart

  Lebeche, D.

  National Heart, Lung, and Blood Institute

  1/04/17 → 31/03/21

  Project: Research

  • Hypertrophic Cardiomyopathy 100%
  • Mutation 98%
  • Heart 93%
  • Phenotype 89%
  • Adiponectin Receptors 65%

• Stress and Atherosclerotic Plaque Macrophages - A Systems Biology Approach

  Fayad, Z., Mani, V., Mulder, W. & Swirski, F.

  National Heart, Lung, and Blood Institute

  17/03/17 → 28/02/22

  Project: Research

  • Systems Biology 100%
  • Atherosclerotic Plaques 87%
  • Atherosclerosis 76%
  • Macrophages 68%
  • Cardiovascular Diseases 45%

• Mechanisms of quiescence and pluripotency in disseminated tumor cells

  Sosa, M. S.

  National Cancer Institute

  15/03/17 → 29/02/20

  Project: Research

  • dormancy 100%
  • neoplasm cells 94%
  • metastasis 40%
  • therapeutics 30%
  • neoplasms 30%

• Prenatal PM2.5 and programming of respiratory outcomes: Placental biomarkers and effect modification by stress

  Lee, A.

  National Heart, Lung, and Blood Institute

  1/03/17 → 28/02/18

  Project: Research

  • Embryonic and Fetal Development 100%
  • Air Pollution 89%
  • Biomarkers 45%
  • Telomere 42%
  • Environmental Exposure 42%

• The impact of HIV-1 infection and its treatment on gastrointestinal B cells

  Mehandru, S.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/03/17 → 28/02/18

  Project: Research

  • HIV-1 100%
  • HIV Infections 94%
  • B-Lymphocytes 92%
  • Immune System 23%
  • Broadly Neutralizing Antibodies 20%

• Innate Immune Surveillance of HIV-1 During Transmission and Systemic Infection

  Chanda, S. K., Garcia-Sastre, A., Chanda, S. S. K. & Garcia-sastre, A. A.

  National Institute of Allergy and Infectious Diseases

  28/02/17 → 31/01/23

  Project: Research

  • Infectious Disease Transmission 100%
  • HIV-1 76%
  • Pattern Recognition Receptors 35%
  • Pathogen-Associated Molecular Pattern Molecules 28%
  • Interferons 25%

• Therapeutic Mechanisms of Cardiac Progenitors in Ischemic Cardiomyopathy

  Fish, K. M., Hajjar, R. & Kovacic, J.

  National Heart, Lung, and Blood Institute

  20/01/17 → 31/12/21

  Project: Research

  • Stem Cell Factor 100%
  • Exosomes 75%
  • Cardiomyopathies 67%
  • Swine 29%
  • Stem Cells 20%

• Characterization of disseminated breast cancer cells and relevance to metastasis

  Sosa, M. S.

  Susan G. Komen

  1/01/17 → 31/12/18

  Project: Research

• 2017-2018 Awards and Grants Awardees

  Watanabe, H.

  American Lung Association

  1/01/17 → 31/12/18

  Project: Research

• PTK6 promotes metastasis, chemoresistance and altered immuno-profiles of TNBC

  Irie, H.

  Susan G. Komen

  1/01/17 → 31/12/18

  Project: Research

• Role of signal sequence variation in governing HIV Env Functions

  Upadhyay, C. & Hioe, C.

  National Institute of Allergy and Infectious Diseases

  1/01/17 → 31/12/19

  Project: Research

  • Protein Sorting Signals 100%
  • Viruses 63%
  • Polysaccharides 57%
  • HIV 51%
  • HIV-1 29%

• The role of extracellular cAMP in the pathogenesis of pulmonary arterial hypertension

  Sassi, Y.

  American Heart Association

  1/01/17 → 31/12/19

  Project: Research

  • Cyclic AMP 100%
  • Pulmonary Arterial Hypertension 87%
  • Vascular Remodeling 28%
  • Pulmonary Artery 22%
  • Blood Vessels 19%

• Targeting the ChREBP-Nrf2 axis to expand functional beta cell mass

  Scott, D.

  American Diabetes Association

  1/01/17 → 31/12/19

  Project: Research

  • Glucose 100%
  • Islets of Langerhans Transplantation 81%
  • Cell Proliferation 62%
  • Transcription Factors 47%
  • Antioxidants 47%

• Targeting the ChREBP-Nrf2 axis to expand functional beta cell mass

  Scott, D.

  1/01/17 → 31/12/19

  Project: Research

  • Glucose 100%
  • Islets of Langerhans Transplantation 81%
  • Cell Proliferation 62%
  • Transcription Factors 47%
  • Antioxidants 47%

• Role of microRNA-146a as a SUMO1 regulator

  Oh, J. G.

  American Heart Association

  1/01/17 → 31/12/18

  Project: Research

  • Ubiquitin 100%
  • Heart Failure 72%
  • MicroRNAs 52%
  • Cardiac Myocytes 46%
  • Sarcoplasmic Reticulum Calcium-Transporting ATPases 18%

• m6A Methylation of mRNA as a Novel Mechanism of Cardiac Repair by Human Stem Cell-Derived Exosomes

  Sahoo, S.

  American Heart Association

  1/01/17 → 31/12/18

  Project: Research

  • Exosomes 100%
  • Methylation 83%
  • Stem Cells 83%
  • Cell- and Tissue-Based Therapy 57%
  • Cardiac Myocytes 56%

• Role of PKP2 in epicardial structure and function

  Delmar, M., Morley, G. & Small, E. M.

  National Heart, Lung, and Blood Institute

  15/12/16 → 30/11/21

  Project: Research

  • Plakophilins 100%
  • Intercellular Junctions 30%
  • Arrhythmogenic Right Ventricular Dysplasia 27%
  • Pericardium 14%
  • Fibroblasts 14%

• CENTERS OF EXCELLENCE FOR INFLUENZA RESEARCH AND SURVEILLANCE (CEIRS)

  Garcia-Sastre, A.

  1/10/16 → 30/09/17

  Project: Research

  • Orthomyxoviridae 100%
  • Human Influenza 91%
  • Cross Protection 70%
  • Pandemics 52%
  • Virulence 43%

• CENTERS OF EXCELLENCE FOR INFLUENZA RESEARCH AND SURVEILLANCE (CEIRS)

  Garcia-Sastre, A.

  1/10/16 → 30/09/17

  Project: Research

  • Orthomyxoviridae 100%
  • Human Influenza 91%
  • Cross Protection 70%
  • Pandemics 52%
  • Virulence 43%

• Multiethnic Fine-Mapping of Polycystic Ovary Syndrome Susceptibility Loci

  Dunaif, A. E., Chen, Z., Dunaif, A. & Hayes, G. M.

  National Institute of Child Health and Human Development

  30/09/16 → 30/06/21

  Project: Research

  • Polycystic Ovary Syndrome 100%
  • Genetic Loci 40%
  • Phenotype 19%
  • Follicle Stimulating Hormone 18%
  • Luteinizing Hormone 17%

• EHR-based Universal Medication Schedule to Improve Adherence to Complex Regimens

  Wolf, M. S. & Federman, A.

  National Institute of Nursing Research

  26/09/16 → 31/07/21

  Project: Research

  • Electronic Health Records 100%
  • Appointments and Schedules 88%
  • Text Messaging 32%
  • Primary Health Care 25%
  • Pharmacy 16%

• Regulation of Adipose Tissue Metabolism by Central Insulin and Leptin

  Buettner, C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  15/09/16 → 14/09/17

  Project: Research

  • White Adipose Tissue 100%
  • Lipogenesis 64%
  • Leptin 55%
  • Insulin 40%
  • Adipose Tissue 40%

• Dissecting the cellular and molecular immune interactions in human atherosclerosis

  Giannarelli, C.

  National Heart, Lung, and Blood Institute

  15/09/16 → 31/08/19

  Project: Research

  • Atherosclerosis 100%
  • Cardiovascular Diseases 67%
  • Systems Biology 55%
  • Immune System 49%
  • Anti-Inflammatory Agents 22%

• Network-driven drug repurposing approaches to treat coronary artery disease

  Giannarelli, C. & Bjorkegren, J.

  National Center for Advancing Translational Sciences

  1/09/16 → 31/07/19

  Project: Research

  • Drug Repositioning 100%
  • Coronary Artery Disease 76%
  • Foam Cells 63%
  • Atherosclerosis 61%
  • In Vitro Techniques 16%

• INCIDENCE, LATENCY, AND SURVIVAL OF CANCER FOLLOWING WORLD TRADE CENTER EXPOSURE

  Hall, C. B. C. B. & Boffetta, P.

  National Institute for Occupational Safety and Health

  1/09/16 → 31/08/20

  Project: Research

  • Survival 100%
  • Incidence 98%
  • Neoplasms 87%
  • Furans 84%
  • Occupational Groups 71%

• MECHANISMS OF ACQUIRED RESISTANCE TO SORAFENIB IN HEPATOCELLULAR CARCINOMA

  Villanueva Rodriguez, A.

  Congressionally Directed Medical Research Programs

  1/09/16 → 31/08/19

  Project: Research

  • Sorafenib 100%
  • Hepatocellular Carcinoma 56%
  • Organoids 19%
  • Veterans 12%
  • Heterografts 10%

• Genes and miRNAs controlled by ORAI3 in cardiovascular remodeling

  Lebeche, D. & Trebak, M.

  National Institute on Aging

  1/09/16 → 31/05/19

  Project: Research

  • Stromal Interaction Molecule 1 100%
  • Muscle Cells 42%
  • MicroRNAs 39%
  • Vascular Remodeling 36%
  • Ion Channels 30%

• Mechanism of Acquired Resistance to Sorafenib in HCC

  Llovet, J.

  U.S. Army

  1/09/16 → 1/09/16

  Project: Research

  • Sorafenib 100%
  • Neoplasms 27%
  • Drug Combinations 22%
  • Drug Resistance 19%
  • Animal Models 15%

• MECHANISMS OF ACQUIRED RESISTANCE TO SORAFENIB IN HEPATOCELLULAR CARCINOMA

  Friedman, S.

  Congressionally Directed Medical Research Programs

  1/09/16 → 31/08/19

  Project: Research

  • Sorafenib 100%
  • Hepatocellular Carcinoma 56%
  • Organoids 19%
  • Veterans 12%
  • Heterografts 10%

• PET/MRI of the brain-hematopoiesis-atherosclerosis axis in PTSD patients

  Fayad, Z.

  National Heart, Lung, and Blood Institute

  1/09/16 → 28/02/22

  Project: Research

  • Post-Traumatic Stress Disorders 100%
  • Hematopoiesis 97%
  • Atherosclerosis 78%
  • Magnetic Resonance Imaging 62%
  • Inflammation 48%

• MECHANISM OF ACQUIRED RESISTANCE TO SORAFENIB IN HCC

  Llovet, J.

  Congressionally Directed Medical Research Programs

  1/09/16 → 31/08/19

  Project: Research

  • Sorafenib 100%
  • Hepatocellular Carcinoma 56%
  • Organoids 19%
  • Veterans 12%
  • Heterografts 10%

• IMPACT OF WTC DUST ON IMMUNE FUNCTIONS AND PROSTATE CANCER PROMOTION

  Aaronson, S.

  National Institute for Occupational Safety and Health

  1/09/16 → 31/08/21

  Project: Research

  • Dust 100%
  • Prostatic Neoplasms 54%
  • Neoplasms 29%
  • Prostate 28%
  • Occupational Groups 24%

• INCIDENCE, LATENCY, AND SURVIVAL OF CANCER FOLLOWING WORLD TRADE CENTER EXPOSURE

  Hall, C. B. C. B. & Boffetta, P.

  National Institute for Occupational Safety and Health

  1/09/16 → 31/08/20

  Project: Research

  • Survival 100%
  • Incidence 98%
  • Neoplasms 87%
  • Furans 84%
  • Occupational Groups 71%

• HEPATITIS C VIRUS INFECTION IN WTC RESPONDERS

  Factor, S. H. S. H. & Boffetta, P.

  National Institute for Occupational Safety and Health

  1/09/16 → 31/08/18

  Project: Research

  • Hepacivirus 100%
  • Virus Diseases 43%
  • Infections 32%
  • Chronic Hepatitis C 23%
  • Referral and Consultation 16%

• INCIDENCE, LATENCY, AND SURVIVAL OF CANCER FOLLOWING WORLD TRADE CENTER EXPOSURE

  Hall, C. B. C. B. & Boffetta, P.

  National Institute for Occupational Safety and Health

  1/09/16 → 31/08/20

  Project: Research

  • Survival 100%
  • Incidence 98%
  • Neoplasms 87%
  • Furans 84%
  • Occupational Groups 71%

• Stress and atherosclerotic plaque macrophages - a systems biology approach

  Fayad, Z.

  National Heart, Lung, and Blood Institute

  1/09/16 → 28/02/22

  Project: Research

  • Biostatistics 100%
  • Macrophages 85%
  • Systems Biology 66%
  • Information management 35%

• Lineage marking in humanized mice to reveal HIV-1 reservoirs

  Chen, B.

  National Institute of Allergy and Infectious Diseases

  1/09/16 → 31/08/20

  Project: Research

  • HIV-1 100%
  • HIV 58%
  • Hematopoietic Stem Cells 27%
  • Highly Active Antiretroviral Therapy 21%
  • Immune System 14%

• HEPATITIS C VIRUS INFECTION IN WTC RESPONDERS

  Factor, S. H. S. H. & Boffetta, P.

  National Institute for Occupational Safety and Health

  1/09/16 → 31/08/18

  Project: Research

  • Hepacivirus 100%
  • Virus Diseases 43%
  • Infections 32%
  • Chronic Hepatitis C 23%
  • Referral and Consultation 16%

• Mechanisms of Acquired Resistance to Sorafenib in Hepatocellular Carcinoma

  Villanueva Rodriguez, A.

  U.S. Army

  1/09/16 → 1/09/16

  Project: Research

  • Sorafenib 100%
  • Hepatocellular Carcinoma 43%
  • Neoplasms 27%
  • Drug Combinations 22%
  • Drug Resistance 19%

• Mechanisms of Acquired Resistance to Sorafenib in Hepatocellular Carcinoma

  Friedman, S.

  U.S. Army

  1/09/16 → 1/09/16

  Project: Research

  • Sorafenib 100%
  • Hepatocellular Carcinoma 43%
  • Neoplasms 27%
  • Drug Combinations 22%
  • Drug Resistance 19%

• Optimizing Treatment of Lung Cancer Patients with Comorbidities

  Wisnivesky, J. P. & Kong, C.

  National Cancer Institute

  19/08/16 → 31/07/21

  Project: Research

  • Lung Neoplasms 100%
  • Comorbidity 97%
  • Lung Diseases 32%
  • Heart Diseases 29%
  • Chronic Disease 27%

• MULTISPECIES, INTEGRATIVE GWAS FOR FOCAL SEGMENTAL GLOMERULOSCLEROSIS

  Gharavi, A.

  Congressionally Directed Medical Research Programs

  15/08/16 → 14/08/19

  Project: Research

  • Focal Segmental Glomerulosclerosis 100%
  • Genome-Wide Association Study 51%
  • Human Genetics 10%
  • Chronic Renal Insufficiency 8%
  • Chronic Kidney Failure 7%

• Multispecies, Integrative GWAS for Focal Segmental Glomerulosclerosis

  Gharavi, A.

  U.S. Army

  15/08/16 → 15/08/16

  Project: Research

  • Focal Segmental Glomerulosclerosis 100%
  • Genome-Wide Association Study 47%
  • Military Family 11%
  • Datasets 11%
  • Kidney Glomerulus 11%

• Risk Clustering and Stratification in Genetically High-Risk Individuals Using Electronic Medical Records and Biomarkers

  Nadkarni, G.

  National Institute of Diabetes and Digestive and Kidney Diseases

  15/08/16 → 31/05/21

  Project: Research

  • Electronic Health Records 100%
  • Cluster Analysis 86%
  • Biomarkers 66%
  • Hispanic Americans 44%
  • African Americans 24%

• Role of desmosomes in cardiac electrical function

  Delmar, M. & Morley, G.

  National Heart, Lung, and Blood Institute

  15/08/16 → 30/06/21

  Project: Research

  • Plakophilins 100%
  • Desmosomes 64%
  • Arrhythmogenic Right Ventricular Dysplasia 24%
  • Cardiac Arrhythmias 15%
  • Phenotype 10%

• The Role of MMSET in the Pathogenesis and Progression of Lymphoid Malignancy

  Licht, J.

  National Cancer Institute

  11/08/16 → 31/07/21

  Project: Research

  • Precursor Cell Lymphoblastic Leukemia-Lymphoma 100%
  • Multiple Myeloma 86%
  • Mutation 48%
  • Genes 35%
  • Preliminary Data 31%

• Targeting HIV persistence in CD4+ T memory stem cells

  Simon, V.

  National Institute of Allergy and Infectious Diseases

  10/08/16 → 31/07/17

  Project: Research

  • HIV 100%
  • Stem Cells 74%
  • Memory 63%
  • Proviruses 59%
  • HIV Infections 40%

• INNATE IMMUNE PATHWAYS AND THE MICROBIOME IN HISPANICS WITH INFLAMMATORY BOWEL DISEASE

  McCauley, J. L. & Abreu, M.

  National Institute of Diabetes and Digestive and Kidney Diseases

  10/08/16 → 31/07/20

  Project: Research

  • Hispanic Americans 100%
  • Inflammatory Bowel Diseases 83%
  • Microbiota 81%
  • Mucous Membrane 15%
  • European Continental Ancestry Group 11%

• Project 3: The Role of Erythropoietin in Kidney Transplant Tolerance

  Heeger, P.

  National Institute of Allergy and Infectious Diseases

  5/08/16 → 31/07/21

  Project: Research

  • Erythropoietin 100%
  • Transplantation Tolerance 65%
  • Transplants 54%
  • Kidney 51%
  • Allografts 24%