Institute for Next Generation Healthcare

Icahn School of Medicine at Mount Sinai

Alessandro Laganà
Person
20072026

21834 Citations
69 h-index
186 Article
28 Review article
17 Comment/debate
13 Chapter
More

A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma
Immune Atlas Consortium, Jan 2026, In: Nature Cancer. 7, 1, p. 224-246 23 p.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma
Ohlstrom, D. J., Pilcher, W. C., Michaud, M. E., Acharya, C., Satpathy, S., Gonzalez-Kozlova, E., Jayasinghe, R. G., Ferguson, K., Mumme, H. L., Nanda, S., Song, Y., Mantrala, S., Karagkouni, D., Schulman, J., Pabustan, N., Vieira Dos Santos, J., Sherbenou, D. W., Keats, J. J., Gout, A. M. & Foltz, S. & 16 others, Lagana, A., Kourelis, T., Vij, R., Dhodapkar, M. V., Avigan, D., Cho, H. J., Baughn, L. B., Nooka, A. K., Lonial, S., Kumar, S., Samur, M. K., Vlachos, I. S., Ding, L., Gnjatic, S., Mulligan, G. & Bhasin, M. K., 4 Mar 2026, In: Blood cancer discovery. 7, 2, p. 266-286 21 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Long-term remission after cilta-cel in multiple myeloma is linked to diverse T cells and low myeloid suppression
Vieira dos Santos, J., Melnekoff, D. T., Aleman, A., Mouhieddine, T. H., Montes de Oca, R., Wang, F., Rajeeve, S., Bhalla, S., Van Oekelen, O., Upadhyaya, B., Ghodke-Puranik, Y., Leshchenko, V., Kim-Schulze, S., Rahman, A., Afik, S., Lewinsky, H., Plaks, V., Thibaud, S., Cho, H. J. & Richter, J. & 9 others, Rodriguez, C., Sanchez, L., Rossi, A., Richard, S., Chari, A., Madduri, D., Jagannath, S., Parekh, S. & Laganà, A., 10 Feb 2026, In: Blood advances. 10, 3, p. 604-607 4 p.
Research output: Contribution to journal › Article › peer-review

Open Access
FaMMily Affairs: Dissecting inherited contributions to multiple myeloma risk
Bodnar, S., Brander, T., Gold, J., Iverson, A., Lagana, A., Onel, K., Jagannath, S., Parekh, S. & Thibaud, S., Feb 2025, In: Seminars in Hematology. 62, 1, p. 11-19 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
Melanoma antigen genes (MAGE); novel functional targets in multiple myeloma
Mei, A. H. C., Laganà, A., Osman, R. & Cho, H. J., Feb 2025, In: Seminars in Hematology. 62, 1, p. 43-49 7 p.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
Targeted Therapy of CAR+ T-Cell Lymphoma after Anti-BCMA CAR T-Cell Therapy
Aleman, A., Van Oekelen, O., Melnekoff, D. T., Grossman, L., Mouhieddine, T. H., Kurowski, A., Odak, I., Reci, S., Desai, S., Meledathu, S., Naidu, M. P., Shukla, R. P., Dutta, R. P., Kappes, K., Serebryakova, K., Jackson, H., Lu, J., Chatikhine, A., Kulkarni, R. & Moinfar, Z. & 15 others, Croken, M. M., Mehrotra, M., Baskovich, B., Rayamajhi, S., Richard, S., Rossi, A. C., Salib, C., Houldsworth, J., Brown, B. D., Merad, M., Laganà, A., Brunner, P. M., Jagannath, S., Brody, J. D. & Parekh, S., 21 Aug 2025, In: New England Journal of Medicine. 393, 8, p. 823-825 3 p.
Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations
The role of 1q abnormalities in multiple myeloma: Genomic insights, clinical implications, and therapeutic challenges
Avigan, Z. M., Mitsiades, C. S. & Laganà, A., Feb 2025, In: Seminars in Hematology. 62, 1, p. 20-30 11 p.
Research output: Contribution to journal › Article › peer-review
8 Scopus citations
Utilizing RADAR for the Integration of Genomic Data and Immunotherapy Targets in Precision Oncology for Multiple Myeloma
Laganà, A., Sariya, S., Melnekoff, D. T., Ram, M. & Parekh, S., 21 Aug 2025, Cancer Detection and Diagnosis: A Handbook of Emerging Technologies. CRC Press, p. 280-294 15 p.
Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Iberdomide increases innate and adaptive immune cell subsets in the bone marrow of patients with relapsed/refractory multiple myeloma
Van Oekelen, O., Amatangelo, M., Guo, M., Upadhyaya, B., Cribbs, A. P., Kelly, G., Patel, M., Kim-Schulze, S., Flynt, E., Lagana, A., Gooding, S., Merad, M., Jagganath, S., Pierceall, W. E., Oppermann, U., Thakurta, A. & Parekh, S., 18 Jun 2024, In: Cell Reports Medicine. 5, 6, 101584.
Research output: Contribution to journal › Article › peer-review

Open Access
14 Scopus citations
Multiple Myeloma Risk and Outcomes Are Associated with Pathogenic Germline Variants in DNA Repair Genes
Thibaud, S., Subaran, R. L., Newman, S., Lagana, A., Melnekoff, D. T., Bodnar, S., Ram, M., Soens, Z., Genthe, W., Brander, T., Mouhieddine, T. H., Van Oekelen, O., Houldsworth, J., Cho, H. J., Richard, S., Richter, J., Rodriguez, C., Rossi, A., Sanchez, L. & Chari, A. & 4 others, Moshier, E., Jagannath, S., Parekh, S. & Onel, K., 1 Nov 2024, In: Blood cancer discovery. 5, 6, p. 428-441 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
17 Scopus citations
Predictors of response to venetoclax and therapeutic potential of CDK7 inhibition in multiple myeloma
Dutta, R. P., Thibaud, S., Leshchenko, V., Ram, M., Melnekoff, D. T., Bhalla, S., Restrepo, P., Gupta, V. A., Barwick, B. G., Newman, S., McCafferty, J., Hantash, F., Nooka, A. K., Cho, H. J., Richard, S., Rodriguez, C., Rossi, A., Sanchez, L., Chari, A. & Boise, L. H. & 4 others, Jagannath, S., Richter, J., Parekh, S. & Laganà, A., Dec 2024, In: Blood Neoplasia. 1, 4, 100049.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
The Genetic and Molecular Drivers of Multiple Myeloma: Current Insights, Clinical Implications, and the Path Forward
Ram, M., Fraser, M. R., Dos Santos, J. V., Tasakis, R., Islam, A., Abo-Donia, J. U., Parekh, S. & Lagana, A., 2024, In: Pharmacogenomics and Personalized Medicine. 17, p. 573-609 37 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
8 Scopus citations

BIDMC Researchers Help Define Risk in Multiple Myeloma Using Tumor Microenvironment Analysis
Nie, K., Kim-Schulze, S., D'Souza, D., Rahman, A., Laganà, A., Cho, H., Gnjatic, S. & Chen, Z.
9/01/26
2 items of Media coverage
Press/Media
BIDMC Researchers Help Define Risk in Multiple Myeloma Using Tumor Microenvironment Analysis
Nie, K., Kim-Schulze, S., D'Souza, D., Rahman, A., Laganà, A., Cho, H., Gnjatic, S. & Chen, Z.
9/01/26
1 item of Media coverage
Press/Media
Mount Sinai Showcases Hematology Research at the 67th ASH Annual Meeting
Shih, A., Mouhieddine, T., Papapetrou, E., Parekh, S., Laganà, A., Jagannath, S., Marron, T., Tremblay, D., Brody, J., Ferrara, J., Mascarenhas, J., Wagenblast, E., Curtis, S. & Dutta, R. P.
3/12/25 → 4/12/25
3 items of Media coverage
Press/Media
HMN 2025: why some myeloma patients stay cancer-free for years after CAR T therapy
Laganà, A.
21/11/25
1 item of Media coverage
Press/Media
Patient Immune System Characteristics and Long-Term Remission From CAR T-Cell Therapy in Multiple Myeloma
Laganà, A.
20/11/25
1 item of Media coverage
Press/Media
Cilta-Cel Remission: Immune Synergy Explained
Laganà, A.
18/11/25
1 item of Media coverage
Press/Media
Mount Sinai Study Reveals Why Some Myeloma Patients Stay Cancer-Free for Years After CAR T Therapy
Laganà, A.
12/11/25 → 13/11/25
7 items of Media coverage
Press/Media
Mount Sinai Study Uncovers Why Certain Myeloma Patients Remain Cancer-Free Long After CAR T Therapy
Laganà, A.
12/11/25
2 items of Media coverage
Press/Media
Researchers at Leicester General Hospital Publish New Data on Proinsulin (Comparison of the effectiveness of fast-acting insulin aspart with rapid-acting insulin analogues on glycaemic control: a retrospective cohort study using patient data ...)
Jensen, A.
11/11/25
1 item of Media coverage
Press/Media
Mount Sinai Researchers Pioneer First Targeted Therapy for Rare T-Cell Lymphoma After CAR T Treatment
Merad, M., Mouhieddine, T., Parekh, S., Laganà, A., Brown, B., Jagannath, S., Brody, J., Brunner, P., Baskovich, B., Odak, I., Dutta, R. P. & Melnekoff, D.
21/08/25 → 22/08/25
5 items of Media coverage
Press/Media
Spar Nord Bank's Extraordinary Meeting Highlights and Changes
Jensen, A.
24/06/25
1 item of Media coverage
Press/Media
Proceedings Of The Extraordinary General Meeting Of Spar Nord Bank A/S
Jensen, A.
24/06/25
1 item of Media coverage
Press/Media

Institute for Next Generation Healthcare

Fingerprint

Collaborations and top research areas from the last five years

Dive into details

Alessandro Laganà

A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma

Longitudinal Profiling of Tumor and Immune Compartments Uncovers Patterns of Dysregulation and Associations with Response in Multiple Myeloma

Long-term remission after cilta-cel in multiple myeloma is linked to diverse T cells and low myeloid suppression

FaMMily Affairs: Dissecting inherited contributions to multiple myeloma risk

Melanoma antigen genes (MAGE); novel functional targets in multiple myeloma

Targeted Therapy of CAR+ T-Cell Lymphoma after Anti-BCMA CAR T-Cell Therapy

The role of 1q abnormalities in multiple myeloma: Genomic insights, clinical implications, and therapeutic challenges

Utilizing RADAR for the Integration of Genomic Data and Immunotherapy Targets in Precision Oncology for Multiple Myeloma

Iberdomide increases innate and adaptive immune cell subsets in the bone marrow of patients with relapsed/refractory multiple myeloma

Multiple Myeloma Risk and Outcomes Are Associated with Pathogenic Germline Variants in DNA Repair Genes

Predictors of response to venetoclax and therapeutic potential of CDK7 inhibition in multiple myeloma

The Genetic and Molecular Drivers of Multiple Myeloma: Current Insights, Clinical Implications, and the Path Forward

BIDMC Researchers Help Define Risk in Multiple Myeloma Using Tumor Microenvironment Analysis

BIDMC Researchers Help Define Risk in Multiple Myeloma Using Tumor Microenvironment Analysis

Mount Sinai Showcases Hematology Research at the 67th ASH Annual Meeting

HMN 2025: why some myeloma patients stay cancer-free for years after CAR T therapy

Patient Immune System Characteristics and Long-Term Remission From CAR T-Cell Therapy in Multiple Myeloma

Cilta-Cel Remission: Immune Synergy Explained

Mount Sinai Study Reveals Why Some Myeloma Patients Stay Cancer-Free for Years After CAR T Therapy

Mount Sinai Study Uncovers Why Certain Myeloma Patients Remain Cancer-Free Long After CAR T Therapy

Researchers at Leicester General Hospital Publish New Data on Proinsulin (Comparison of the effectiveness of fast-acting insulin aspart with rapid-acting insulin analogues on glycaemic control: a retrospective cohort study using patient data ...)

Mount Sinai Researchers Pioneer First Targeted Therapy for Rare T-Cell Lymphoma After CAR T Treatment

Spar Nord Bank's Extraordinary Meeting Highlights and Changes

Proceedings Of The Extraordinary General Meeting Of Spar Nord Bank A/S

Institute for Next Generation Healthcare

Fingerprint

Collaborations and top research areas from the last five years

Profiles

Research output

Press/Media