Institute for Exposomic Research

2023

DDX3X Syndrome: Summary of Findings and Recommendations for Evaluation and Care

Levy, T., Siper, P. M., Lerman, B., Halpern, D., Zweifach, J., Belani, P., Thurm, A., Kleefstra, T., Berry-Kravis, E., Buxbaum, J. D. & Grice, D. E., Jan 2023, In: Pediatric Neurology. 138, p. 87-94 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Human 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure and thyroid cancer risk

van Gerwen, M., Vasan, V., Genden, E. & Saul, S. R., Apr 2023, In: Toxicology. 488, 153474.

Research output: Contribution to journal › Review article › peer-review

Navigating the pitfalls of mapping DNA and RNA modifications

Kong, Y., Mead, E. A. & Fang, G., 2023, (Accepted/In press) In: Nature Reviews Genetics.

Research output: Contribution to journal › Review article › peer-review

Psychosis spectrum illnesses as disorders of prefrontal critical period plasticity

Vinogradov, S., Chafee, M. V., Lee, E. & Morishita, H., Jan 2023, In: Neuropsychopharmacology. 48, 1, p. 168-185 18 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Understanding Neuropeptide Transmission in the Brain by Optical Uncaging and Release

Xiong, H., Wilson, B. A., Slesinger, P. A. & Qin, Z., 15 Feb 2023, In: ACS Chemical Neuroscience. 14, 4, p. 516-523 8 p.

Research output: Contribution to journal › Review article › peer-review

2022

AI/ML-driven advances in untargeted metabolomics and exposomics for biomedical applications

Petrick, L. M. & Shomron, N., 20 Jul 2022, In: Cell Reports Physical Science. 3, 7, 100978.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

Allergies to food and airborne allergens in children and adolescents: role of epigenetics in a changing environment

Melén, E., Koppelman, G. H., Vicedo-Cabrera, A. M., Andersen, Z. J. & Bunyavanich, S., Nov 2022, In: The Lancet Child and Adolescent Health. 6, 11, p. 810-819 10 p.

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus

Ekhtiari, H., Zare-Bidoky, M., Sangchooli, A., Janes, A. C., Kaufman, M. J., Oliver, J. A., Prisciandaro, J. J., Wüstenberg, T., Anton, R. F., Bach, P., Baldacchino, A., Beck, A., Bjork, J. M., Brewer, J., Childress, A. R., Claus, E. D., Courtney, K. E., Ebrahimi, M., Filbey, F. M., Ghahremani, D. G., & 40 othersAzbari, P. G., Goldstein, R. Z., Goudriaan, A. E., Grodin, E. N., Hamilton, J. P., Hanlon, C. A., Hassani-Abharian, P., Heinz, A., Joseph, J. E., Kiefer, F., Zonoozi, A. K., Kober, H., Kuplicki, R., Li, Q., London, E. D., McClernon, J., Noori, H. R., Owens, M. M., Paulus, M. P., Perini, I., Potenza, M., Potvin, S., Ray, L., Schacht, J. P., Seo, D., Sinha, R., Smolka, M. N., Spanagel, R., Steele, V. R., Stein, E. A., Steins-Loeber, S., Tapert, S. F., Verdejo-Garcia, A., Vollstädt-Klein, S., Wetherill, R. R., Wilson, S. J., Witkiewitz, K., Yuan, K., Zhang, X. & Zilverstand, A., Mar 2022, In: Nature Protocols. 17, 3, p. 567-595 29 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

Assessing Differential Variability of High-Throughput DNA Methylation Data

Saddiki, H., Colicino, E. & Lesseur, C., Dec 2022, In: Current Environmental Health Reports. 9, 4, p. 625-630 6 p.

Research output: Contribution to journal › Review article › peer-review

Association of Personal Characteristics and Effectiveness of Immunotherapy in Late-Stage Non-Small Cell Lung Cancer: A Systematic Review

Patel, K., Alpert, N., Tuminello, S. & Taioli, E., 1 Apr 2022, In: JNCI Cancer Spectrum. 6, 2, pkac015.

Research output: Contribution to journal › Review article › peer-review

Open Access

Astrocytes in cocaine addiction and beyond

Wang, J., Holt, L. M., Huang, H. H., Sesack, S. R., Nestler, E. J. & Dong, Y., Jan 2022, In: Molecular Psychiatry. 27, 1, p. 652-668 17 p.

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Beyond the neuron: Role of non-neuronal cells in stress disorders

Cathomas, F., Holt, L. M., Parise, E. M., Liu, J., Murrough, J. W., Casaccia, P., Nestler, E. J. & Russo, S. J., 6 Apr 2022, In: Neuron. 110, 7, p. 1116-1138 23 p.

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Cancer risk among World Trade Center rescue and recovery workers: A review

Boffetta, P., Hall, C. B., Todd, A. C., Goldfarb, D. G., Schymura, M. J., Li, J., Cone, J. E. & Zeig-Owens, R., 1 Jul 2022, In: Ca-A Cancer Journal for Clinicians. 72, 4, p. 308-314 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Circadian Rhythm Disruption as a Contributor to Racial Disparities in Prostate Cancer

Dasari, S. S., Archer, M., Mohamed, N. E., Tewari, A. K., Figueiro, M. G. & Kyprianou, N., Oct 2022, In: Cancers. 14, 20, 5116.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Cognitive impairment and World Trade Centre-related exposures

Clouston, S. A. P., Hall, C. B., Kritikos, M., Bennett, D. A., DeKosky, S., Edwards, J., Finch, C., Kreisl, W. C., Mielke, M., Peskind, E. R., Raskind, M., Richards, M., Sloan, R. P., Spiro, A., Vasdev, N., Brackbill, R., Farfel, M., Horton, M., Lowe, S., Lucchini, R. G., & 12 othersPrezant, D., Reibman, J., Rosen, R., Seil, K., Zeig-Owens, R., Deri, Y., Diminich, E. D., Fausto, B. A., Gandy, S., Sano, M., Bromet, E. J. & Luft, B. J., Feb 2022, In: Nature Reviews Neurology. 18, 2, p. 103-116 14 p.

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Disease Burden and Unmet Need in Eosinophilic Esophagitis

Bredenoord, A. J., Patel, K., Schoepfer, A. M., Dellon, E. S., Chehade, M., Aceves, S. S., Spergel, J. M., Shumel, B., Deniz, Y., Rowe, P. J. & Jacob-Nara, J. A., 1 Aug 2022, In: American Journal of Gastroenterology. 117, 8, p. 1231-1241 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Economic Evaluation of Prenatal and Postpartum Care in Women With Gestational Diabetes and Hypertensive Disorders of Pregnancy: A Systematic Review

Li, W., Kim, C. S., Howell, E. A., Janevic, T., Liu, B., Shi, L. & Li, Y., Dec 2022, In: Value in Health. 25, 12, p. 2062-2080 19 p.

Research output: Contribution to journal › Review article › peer-review

Environmental exposures: Evolving evidence for their roles in adult allergic disorders

Harada, K. & Miller, R. L., 2022, In: Current Opinion in Allergy and Clinical Immunology. 22, 1, p. 24-28 5 p.

Research output: Contribution to journal › Review article › peer-review

Environmental Metal Exposure, Neurodevelopment, and the Role of Iron Status: a Review

Schildroth, S., Kordas, K., Bauer, J. A., Wright, R. O. & Claus Henn, B., Dec 2022, In: Current Environmental Health Reports. 9, 4, p. 758-787 30 p.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Eosinophilic esophagitis: Immune mechanisms and therapeutic targets

Khokhar, D., Marella, S., Idelman, G., Chang, J. W., Chehade, M. & Hogan, S. P., Oct 2022, In: Clinical and Experimental Allergy. 52, 10, p. 1142-1156 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

Exposure to per-and Polyfluoroalkyl Substances and Markers of Liver Injury: A Systematic Review and Meta-Analysis

Costello, E., Rock, S., Stratakis, N., Eckel, S. P., Walker, D. I., Valvi, D., Cserbik, D., Jenkins, T., Xanthakos, S. A., Kohli, R., Sisley, S., Vasiliou, V., La Merrill, M. A., Rosen, H., Conti, D. V., McConnell, R. & Chatzi, L., Apr 2022, In: Environmental Health Perspectives. 130, 4, 046001.

Research output: Contribution to journal › Review article › peer-review

Open Access

23 Scopus citations

Gene-based therapeutics for rare genetic neurodevelopmental psychiatric disorders

Gene Therapy Workshop Faculty, 6 Jul 2022, In: Molecular Therapy. 30, 7, p. 2416-2428 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

Hypertrophic Cardiomyopathy in RASopathies: Diagnosis, Clinical Characteristics, Prognostic Implications, and Management

Lioncino, M., Monda, E., Verrillo, F., Moscarella, E., Calcagni, G., Drago, F., Marino, B., Digilio, M. C., Putotto, C., Calabrò, P., Russo, M. G., Roberts, A. E., Gelb, B. D., Tartaglia, M. & Limongelli, G., Jan 2022, In: Heart Failure Clinics. 18, 1, p. 19-29 11 p.

Research output: Contribution to journal › Review article › peer-review

10 Scopus citations

Impact of Circadian Rhythms on the Development and Clinical Management of Genitourinary Cancers

Kaur, P., Mohamed, N. E., Archer, M., Figueiro, M. G. & Kyprianou, N., 9 Mar 2022, In: Frontiers in Oncology. 12, 759153.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Inflammatory Diseases of the Aorta: JACC Focus Seminar, Part 2

Kadian-Dodov, D., Seo, P., Robson, P. M., Fayad, Z. A. & Olin, J. W., 23 Aug 2022, In: Journal of the American College of Cardiology. 80, 8, p. 832-844 13 p.

Research output: Contribution to journal › Review article › peer-review

It May Not All Be Overdiagnosis: The Potential Role of Environmental Exposures in the Thyroid Cancer Incidence Increase

Van Gerwen, M., Alsen, M. & Genden, E., 1 Sep 2022, In: Epidemiology. 33, 5, p. 607-610 4 p.

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Key transcription factors mediating cocaine-induced plasticity in the nucleus accumbens

Teague, C. D. & Nestler, E. J., Jan 2022, In: Molecular Psychiatry. 27, 1, p. 687-709 23 p.

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Lifespan evolution of neurocognitive impairment in schizophrenia - A narrative review

Fett, A. K. J., Reichenberg, A. & Velthorst, E., Jun 2022, In: Schizophrenia Research: Cognition. 28, 100237.

Research output: Contribution to journal › Review article › peer-review

Open Access

7 Scopus citations

Managing food allergy: GA²LEN guideline 2022

GALEN Food Allergy Guideline Group, Sep 2022, In: World Allergy Organization Journal. 15, 9, 100687.

Research output: Contribution to journal › Review article › peer-review

Open Access

7 Scopus citations

Managing Food Allergy When the Patient Is Not Highly Allergic

Sicherer, S. H., Abrams, E. M., Nowak-Wegrzyn, A. & Hourihane, J. O. B., Jan 2022, In: Journal of Allergy and Clinical Immunology: In Practice. 10, 1, p. 46-55 10 p.

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

MEK inhibitors for neurofibromatosis type 1 manifestations: Clinical evidence and consensus

de Blank, P. M. K., Gross, A. M., Akshintala, S., Blakeley, J. O., Bollag, G., Cannon, A., Dombi, E., Fangusaro, J., Gelb, B. D., Hargrave, D., Kim, A. R., Klesse, L. J., Loh, M., Martin, S., Moertel, C., Packer, R., Payne, J. M., Rauen, K. A., Rios, J. J., Robison, N., & 12 othersSchorry, E. K., Shannon, K., Stevenson, D. A., Stieglitz, E., Ullrich, N. J., Walsh, K. S., Weiss, B. D., Wolters, P. L., Yohay, K., Yohe, M. E., Widemann, B. C. & Fisher, M. J., 2 Nov 2022, In: Neuro-Oncology. 24, 11, p. 1845-1856 12 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Multidisciplinary clinical guidance on trastuzumab deruxtecan (T-DXd)–related interstitial lung disease/pneumonitis—Focus on proactive monitoring, diagnosis, and management

Swain, S. M., Nishino, M., Lancaster, L. H., Li, B. T., Nicholson, A. G., Bartholmai, B. J., Naidoo, J., Schumacher-Wulf, E., Shitara, K., Tsurutani, J., Conte, P., Kato, T., Andre, F. & Powell, C. A., May 2022, In: Cancer Treatment Reviews. 106, 102378.

Research output: Contribution to journal › Review article › peer-review

Open Access

15 Scopus citations

New prospectives on treatment opportunities in RASopathies

Gelb, B. D., Yohe, M. E., Wolf, C. & Andelfinger, G., Dec 2022, In: American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 190, 4, p. 541-560 20 p.

Research output: Contribution to journal › Review article › peer-review

Pediatric and Congenital Cardiovascular Disease Research Challenges and Opportunities: JACC Review Topic of the Week

Opotowsky, A. R., Allen, K. Y., Bucholz, E. M., Burns, K. M., del Nido, P., Fenton, K. N., Gelb, B. D., Kirkpatrick, J. N., Kutty, S., Lambert, L. M., Lopez, K. N., Olivieri, L. J., Pajor, N. M., Pasquali, S. K., Petit, C. J., Sood, E., VanBuren, J. M., Pearson, G. D. & Miyamoto, S. D., 6 Dec 2022, In: Journal of the American College of Cardiology. 80, 23, p. 2239-2250 12 p.

Research output: Contribution to journal › Review article › peer-review

Powering Research through Innovative Methods for Mixtures in Epidemiology (PRIME) Program: Novel and Expanded Statistical Methods

Joubert, B. R., Kioumourtzoglou, M. A., Chamberlain, T., Chen, H. Y., Gennings, C., Turyk, M. E., Miranda, M. L., Webster, T. F., Ensor, K. B., Dunson, D. B. & Coull, B. A., 1 Feb 2022, In: International Journal of Environmental Research and Public Health. 19, 3, 1378.

Research output: Contribution to journal › Review article › peer-review

Open Access

8 Scopus citations

Proposal of 0.5 mg of protein/100 g of processed food as threshold for voluntary declaration of food allergen traces in processed food—A first step in an initiative to better inform patients and avoid fatal allergic reactions: A GA²LEN position paper

Zuberbier, T., Dörr, T., Aberer, W., Alvaro, M., Angier, E., Arasi, S., Arshad, H., Ballmer-Weber, B., Bartra, J., Beck, L., Bégin, P., Bindslev-Jensen, C., Bislimovska, J., Bousquet, J., Brockow, K., Bush, A., Cianferoni, A., Cork, M. J., Custovic, A., Darsow, U., & 65 othersde Jong, N., Deleanu, D., Del Giacco, S., Deschildre, A., Dunn Galvin, A., Ebisawa, M., Fernández-Rivas, M., Ferrer, M., Fiocchi, A., Gerth van Wijk, R., Gotua, M., Grimshaw, K., Grünhagen, J., Heffler, E., Hide, M., Hoffmann-Sommergruber, K., Incorvaia, C., Janson, C., Malte John, S., Jones, C., Jutel, M., Katoh, N., Kendziora, B., Kinaciyan, T., Knol, E., Kurbacheva, O., Lau, S., Loh, R., Lombardi, C., Mäkelä, M., Marchisotto, M. J., Makris, M., Maurer, M., Meyer, R., Mijakoski, D., Minov, J., Mullol, J., Nilsson, C., Nowak–Wegrzyn, A., Nwaru, B. I., Odemyr, M., Pajno, G. B., Paudel, S., Papadopoulos, N. G., Renz, H., Ricci, G., Ring, J., Rogala, B., Sampson, H., Senna, G., Sitkauskiene, B., Smith, P. K., Stevanovic, K., Stoleski, S., Szajewska, H., Tanaka, A., Todo-Bom, A., Topal, F. A., Valovirta, E., Van Ree, R., Venter, C., Wöhrl, S., Wong, G. W. K., Zhao, Z. & Worm, M., Jun 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 6, p. 1736-1750 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

Prospects for precision genetic medicine in congenital heart disease

Gelb, B. D., Dec 2022, In: Current Opinion in Genetics and Development. 77, 101983.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Responding to the opioid crisis in North America and beyond: recommendations of the Stanford–Lancet Commission

Humphreys, K., Shover, C. L., Andrews, C. M., Bohnert, A. S. B., Brandeau, M. L., Caulkins, J. P., Chen, J. H., Cuéllar, M. F., Hurd, Y. L., Juurlink, D. N., Koh, H. K., Krebs, E. E., Lembke, A., Mackey, S. C., Larrimore Ouellette, L., Suffoletto, B. & Timko, C., 5 Feb 2022, In: The Lancet. 399, 10324, p. 555-604 50 p.

Research output: Contribution to journal › Review article › peer-review

48 Scopus citations

Structural and functional brain recovery in individuals with substance use disorders during abstinence: A review of longitudinal neuroimaging studies

Parvaz, M. A., Rabin, R. A., Adams, F. & Goldstein, R. Z., 1 Mar 2022, In: Drug and Alcohol Dependence. 232, 109319.

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

The heart in RASopathies

Delogu, A. B., Limongelli, G., Versacci, P., Adorisio, R., Kaski, J. P., Blandino, R., Maiolo, S., Monda, E., Putotto, C., De Rosa, G., Chatfield, K. C., Gelb, B. D. & Calcagni, G., Dec 2022, In: American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 190, 4, p. 440-451 12 p.

Research output: Contribution to journal › Review article › peer-review

The molecular genetics of RASopathies: An update on novel disease genes and new disorders

Tartaglia, M., Aoki, Y. & Gelb, B. D., Dec 2022, In: American Journal of Medical Genetics, Part C: Seminars in Medical Genetics. 190, 4, p. 425-439 15 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

The neurobiology of drug addiction: cross-species insights into the dysfunction and recovery of the prefrontal cortex

Ceceli, A. O., Bradberry, C. W. & Goldstein, R. Z., Jan 2022, In: Neuropsychopharmacology. 47, 1, p. 276-291 16 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

19 Scopus citations

The role of heavy metals in thyroid cancer: A meta-analysis

van Gerwen, M., Alerte, E., Alsen, M., Little, C., Sinclair, C. & Genden, E., Jan 2022, In: Journal of Trace Elements in Medicine and Biology. 69, 126900.

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

The role of outdoor and indoor air quality in the spread of SARS-CoV-2: Overview and recommendations by the research group on COVID-19 and particulate matter (RESCOP commission)

the RESCOP Commission established by Environmental Research (Elsevier), Aug 2022, In: Environmental Research. 211, 113038.

Research output: Contribution to journal › Review article › peer-review

Open Access

8 Scopus citations

Tumor microenvironment in lung cancer-derived brain metastasis

Liu, W., Powell, C. A. & Wang, Q., 5 Aug 2022, In: Chinese Medical Journal. 135, 15, p. 1781-1791 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Update on Food Protein–Induced Enterocolitis Syndrome (FPIES)

Baker, M. G., Cecilia Berin, M. & Sicherer, S., Oct 2022, In: Current Allergy and Asthma Reports. 22, 10, p. 113-122 10 p.

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

What Is “Socioeconomic Position (SEP),” and How Might It Modify Air Pollution-Health Associations? Cohering Findings, Identifying Challenges, and Disentangling Effects of SEP and Race in US City Settings

Clougherty, J. E., Humphrey, J. L., Kinnee, E. J., Remigio, R. & Sheffield, P. E., Sep 2022, In: Current Environmental Health Reports. 9, 3, p. 355-365 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access