Human Immune Monitoring Center

2024

An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis

LaMarche, N. M., Hegde, S., Park, M. D., Maier, B. B., Troncoso, L., Le Berichel, J., Hamon, P., Belabed, M., Mattiuz, R., Hennequin, C., Chin, T., Reid, A. M., Reyes-Torres, I., Nemeth, E., Zhang, R., Olson, O. C., Doroshow, D. B., Rohs, N. C., Gomez, J. E. & Veluswamy, R. & 18 others, Hall, N., Venturini, N., Ginhoux, F., Liu, Z., Buckup, M., Figueiredo, I., Roudko, V., Miyake, K., Karasuyama, H., Gonzalez-Kozlova, E., Gnjatic, S., Passegué, E., Kim-Schulze, S., Brown, B. D., Hirsch, F. R., Kim, B. S., Marron, T. U. & Merad, M., 4 Jan 2024, In: Nature. 625, 7993, p. 166-174 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

An immunogenetic basis for lung cancer risk

Krishna, C., Tervi, A., Saffern, M., Wilson, E. A., Yoo, S. K., Mars, N., Roudko, V., Cho, B. A., Jones, S. E., Vaninov, N., Selvan, M. E., Gümüş, Z. H., FinnGen, Lenz, T. L., Merad, M., Boffetta, P., Martínez-Jiménez, F., Ollila, H. M., Samstein, R. M. & Chowell, D., 23 Feb 2024, In: Science. 383, 6685, p. 1-18 18 p., eadi3808.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

A Phase II Open-Label Randomized Clinical Trial of Preoperative Durvalumab or Durvalumab plus Tremelimumab in Resectable Head and Neck Squamous Cell Carcinoma

Kim, C. G., Hong, M. H., Kim, D., Lee, B. H., Kim, H., Ock, C. Y., Kelly, G., Bang, Y. J., Kim, G., Lee, J. E., Kim, C., Kim, S. H., Hong, H. J., Park, Y. M., Sim, N. S., Park, H., Park, J. W., Lee, C. G., Kim, K. H. & Park, G. & 17 others, Jung, I., Han, D., Kim, J. H., Cha, J., Lee, I., Kang, M., Song, H., Oum, C., Kim, S., Kim, S., Lim, Y., Kim-Schulze, S., Merad, M., Yoon, S. O., Kim, H. J., Koh, Y. W. & Kim, H. R., 15 May 2024, In: Clinical Cancer Research. 30, 10, p. 2097-2110 14 p.

Research output: Contribution to journal › Article › peer-review

Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma versus other advanced solid tumours

Celsa, C., Cabibbo, G., Fulgenzi, C. A. M., Scheiner, B., D'Alessio, A., Manfredi, G. F., Nishida, N., Ang, C., Marron, T. U., Saeed, A., Wietharn, B., Pinter, M., Cheon, J., Huang, Y. H., Lee, P. C., Phen, S., Gampa, A., Pillai, A., Vivaldi, C. & Salani, F. & 52 others, Masi, G., Roehlen, N., Thimme, R., Vogel, A., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Galle, P. R., Kudo, M., Rimassa, L., Singal, A. G., El Tomb, P., Ulahannan, S., Parisi, A., Chon, H. J., Hsu, W. F., Stefanini, B., Verzoni, E., Giusti, R., Veccia, A., Catino, A., Aprile, G., Guglielmini, P. F., Di Napoli, M., Ermacora, P., Antonuzzo, L., Rossi, E., Verderame, F., Zustovich, F., Ficorella, C., Di Pietro, F. R., Battelli, N., Negrini, G., Grossi, F., Bordonaro, R., Pipitone, S., Banzi, M., Ricciardi, S., Laera, L., Russo, A., De Giorgi, U., Cavanna, L., Sorarù, M., Montesarchio, V., Bordi, P., Brunetti, L., Pinto, C., Bersanelli, M., Cammà, C., Cortellini, A. & Pinato, D. J., Mar 2024, In: Journal of Hepatology. 80, 3, p. 431-442 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Circulating myeloid-derived MMP8 in stress susceptibility and depression

Cathomas, F., Lin, H. Y., Chan, K. L., Li, L., Parise, L. F., Alvarez, J., Durand-de Cuttoli, R., Aubry, A. V., Muhareb, S., Desland, F., Shimo, Y., Ramakrishnan, A., Estill, M., Ferrer-Pérez, C., Parise, E. M., Wilk, C. M., Kaster, M. P., Wang, J., Sowa, A. & Janssen, W. G. & 10 others, Costi, S., Rahman, A., Fernandez, N., Campbell, M., Swirski, F. K., Nestler, E. J., Shen, L., Merad, M., Murrough, J. W. & Russo, S. J., 29 Feb 2024, In: Nature. 626, 8001, p. 1108-1115 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Clinical outcomes and safety of immune checkpoint inhibitors in patients with solid tumors and paraneoplastic syndromes

Nassar, A. H., El Zarif, T., Khalid, A. B., Rahme, S., Zhong, C., Kwak, L., Salame, M., Farhat, E. B., Freeman, D., El-Am, E., Ravishankar, A., Ahmad, B., Nana, F. A., Kaldas, D., Naqash, A. R., Sharon, E., Leboeuf, N. R., Cortellini, A., Malgeri, A. & Gupta, S. & 14 others, Al-Hader, A., Sparks, J. A., Linnoila, J., Hamnvik, O. P. R., Mouhieddine, T. H., Marron, T., Parikh, K., McKay, R. R., Dilling, T., Choueiri, T. K., Adib, E., Najem, E., Kim, S. Y. & Sonpavde, G., 5 Mar 2024, In: Journal for ImmunoTherapy of Cancer. 12, 3, e008724.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Consolidation Osimertinib Versus Durvalumab Versus Observation After Concurrent Chemoradiation in Unresectable EGFR-Mutant NSCLC: A Multicenter Retrospective Cohort Study

Nassar, A. H., Kim, S. Y., Aredo, J. V., Feng, J., Shepherd, F., Xu, C., Kaldas, D., Gray, J. E., Dilling, T. J., Neal, J. W., Wakelee, H. A., Liu, Y., Lin, S. H., Abuali, T., Amini, A., Nie, Y., Patil, T., Lobachov, A., Bar, J. & Fitzgerald, B. & 37 others, Fujiwara, Y., Marron, T. U., Thummalapalli, R., Yu, H., Owen, D. H., Sharp, J., Farid, S., Rocha, P., Arriola, E., D'Aiello, A., Cheng, H., Whitaker, R., Parikh, K., Ashara, Y., Chen, L., Sankar, K., Harris, J. P., Nagasaka, M., Ayanambakkam, A., Velazquez, A. I., Ragavan, M., Lin, J. J., Piotrowska, Z., Wilgucki, M., Reuss, J., Luders, H., Grohe, C., Baena Espinar, J., Feiner, E., Punekar, S. R., Gupta, S., Leal, T., Kwiatkowski, D. J., Mak, R. H., Adib, E., Naqash, A. R. & Goldberg, S. B., Jun 2024, In: Journal of Thoracic Oncology. 19, 6, p. 928-940 13 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

IMPACC Network, IMPACC Steering Committee, Clinical Data Coordinating Center (CDCC), IMPACC Data Analysis Group, IMPACC Site Investigators, IMPACC Core Laboratory & IMPACC Clinical Study Team, Dec 2024, In: Nature Communications. 15, 1, 216.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis

Canales-Herrerias, P., Uzzan, M., Seki, A., Czepielewski, R. S., Verstockt, B., Livanos, A. E., Raso, F., Dunn, A., Dai, D., Wang, A., Al-Taie, Z., Martin, J., Laurent, T., Ko, H. M., Tokuyama, M., Tankelevich, M., Meringer, H., Cossarini, F., Jha, D. & Krek, A. & 25 others, Paulsen, J. D., Taylor, M. D., Nakadar, M. Z., Wong, J., Erlich, E. C., Mintz, R. L., Onufer, E. J., Helmink, B. A., Sharma, K., Rosenstein, A., Ganjian, D., Chung, G., Dawson, T., Juarez, J., Yajnik, V., Cerutti, A., Faith, J. J., Suarez-Farinas, M., Argmann, C., Petralia, F., Randolph, G. J., Polydorides, A. D., Reboldi, A., Colombel, J. F. & Mehandru, S., Apr 2024, In: Science immunology. 9, 94, eadg7549.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

High-dimensional profiling of regulatory T cells in psoriasis reveals an impaired skin-trafficking property

Lee, B. H., Bang, Y. J., Lim, S. H., Kang, S. J., Kim, S. H., Kim-Schulze, S., Park, C. G., Kim, H. J. & Kim, T. G., Feb 2024, In: eBioMedicine. 100, 104985.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology

IMPACC Network, 2024, In: Science Translational Medicine. 16, 743, eadj5154.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Iberdomide increases innate and adaptive immune cell subsets in the bone marrow of patients with relapsed/refractory multiple myeloma

Van Oekelen, O., Amatangelo, M., Guo, M., Upadhyaya, B., Cribbs, A. P., Kelly, G., Patel, M., Kim-Schulze, S., Flynt, E., Lagana, A., Gooding, S., Merad, M., Jagganath, S., Pierceall, W. E., Oppermann, U., Thakurta, A. & Parekh, S., 18 Jun 2024, In: Cell Reports Medicine. 5, 6, 101584.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition

IMPACC Data Analysis Group, IMPACC Site Investigators, IMPACC Core Laboratory, IMPACC Clinical Study Team, IMPACC Network, IMPACC Steering Committee & Clinical & Data Coordinating Center (CDCC), Dec 2024, In: Nature Communications. 15, 1, 404.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Immune and neural response to acute social stress in adolescent humans and rodents

Gabbay, V., Ely, B. A., Vileisis, J. N., Petrovic, Z., Cicvaric, A., Asnis, G. M., Kim-Schulze, S. & Radulovic, J., Dec 2024, In: Translational Psychiatry. 14, 1, 306.

Research output: Contribution to journal › Article › peer-review

Open Access

Immune Assessment Today: Optimizing and Standardizing Efforts to Monitor Immune Responses in Cancer and Beyond

Pandey, S., Cholak, M. E., Yadali, R., Sosman, J. A., Tetreault, M. P., Fang, D., Pollack, S. M., Gnjatic, S., Obeng, R. C., Lyerly, H. K., Sonabend, A. M., Guevara-Patiño, J. A., Butterfield, L. H., Zhang, B., Maecker, H. T. & Le Poole, I. C., Feb 2024, In: Cancers. 16, 3, 475.

Research output: Contribution to journal › Article › peer-review

Open Access

Imprinted immune abnormalities in liver transplant patients cured of hepatitis C with antiviral drugs

Doyle, E. H., Aloman, C., El-Shamy, A., Eng, F. J., Kim-Schulze, S., Rahman, A., Schiano, T., Heeger, P. & Branch, A. D., Jul 2024, In: Liver Transplantation. 30, 7, p. 728-741 14 p.

Research output: Contribution to journal › Article › peer-review

Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality

IMPACC Network, 1 May 2024, In: Journal of Clinical Investigation. 134, 9, e17664.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Mechanisms and Predictive Biomarkers of Allergen Immunotherapy in the Clinic

Layhadi, J. A., Lalioti, A., Palmer, E., van Zelm, M. C., Wambre, E. & Shamji, M. H., Jan 2024, In: Journal of Allergy and Clinical Immunology: In Practice. 12, 1, p. 59-66 8 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Multimodal single-cell analyses reveal mechanisms of perianal fistula in diverse patients with Crohn's disease

Levantovsky, R. M., Tastad, C., Zhang, J., Gettler, K., Sabic, K., Werner, R., Chasteau, C., Korie, U., Paguay, D., Bao, M., Han, H., Maskey, N., Talware, S., Patel, M., Argmann, C., Suarez-Farinas, M., Harpaz, N., Chuang, L. S. & Cho, J. H., 9 Aug 2024, In: Med. 5, 8, p. 886-908.e11

Research output: Contribution to journal › Article › peer-review

Multi-omics Analysis Reveals Immune Features Associated with Immunotherapy Benefit in Patients with Squamous Cell Lung Cancer from Phase III Lung-MAP S1400I Trial

Parra, E. R., Zhang, J., Duose, D. Y., Gonzalez-Kozlova, E., Redman, M. W., Chen, H., Manyam, G. C., Kumar, G., Zhang, J., Song, X., Lazcano, R., Marques-Piubelli, M. L., Laberiano-Fernandez, C., Rojas, F., Zhang, B., Taing, L., Jhaveri, A., Geisberg, J., Altreuter, J. & Michor, F. & 27 others, Provencher, J., Yu, J., Cerami, E., Moravec, R., Kannan, K., Luthra, R., Alatrash, G., Huang, H. H., Xie, H., Patel, M., Nie, K., Harris, J., Argueta, K., Lindsay, J., Biswas, R., Van Nostrand, S., Kim-Schulze, S., Gray, J. E., Herbst, R. S., Wistuba, I. I., Gettinger, S., Kelly, K., Bazhenova, L., Gnjatic, S., Lee, J. J., Zhang, J. & Haymaker, C., 15 Apr 2024, In: Clinical Cancer Research. 30, 8, p. 1655-1668 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Personalized neoantigen vaccine and pembrolizumab in advanced hepatocellular carcinoma: a phase 1/2 trial

Yarchoan, M., Gane, E. J., Marron, T. U., Perales-Linares, R., Yan, J., Cooch, N., Shu, D. H., Fertig, E. J., Kagohara, L. T., Bartha, G., Northcott, J., Lyle, J., Rochestie, S., Peters, J., Connor, J. T., Jaffee, E. M., Csiki, I., Weiner, D. B., Perales-Puchalt, A. & Sardesai, N. Y., Apr 2024, In: Nature Medicine. 30, 4, p. 1044-1053 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Phase 1 study combining elotuzumab with autologous stem cell transplant and lenalidomide for multiple myeloma

Coffey, D. G., Osman, K., Aleman, A., Bekri, S., Kats, S., Dhadwal, A., Catamero, D., Kim-Schulze, S., Gnjatic, S., Chari, A., Parekh, S., Jagannath, S. & Cho, H. J., 12 Apr 2024, In: Journal for ImmunoTherapy of Cancer. 12, 4, e008110.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Phase I study of peposertib and avelumab with or without palliative radiotherapy in patients with advanced solid tumors

Perez, B., Aljumaily, R., Marron, T. U., Shafique, M. R., Burris, H., Iams, W. T., Chmura, S. J., Luke, J. J., Edenfield, W., Sohal, D., Liao, X., Boesler, C., Machl, A., Seebeck, J., Becker, A., Guenther, B., Rodriguez-Gutierrez, A. & Antonia, S. J., Feb 2024, In: ESMO Open. 9, 2, 102217.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Proteomic analysis of cardiovascular disease-associated proteins in Korean patients with moderate-to-severe atopic dermatitis

Jin, S. P., Kim, H., Moon, J. H., Kim-Schulze, S., Chun, Y. S., Nam, H. J., Bang, Y. J., Lee, J. S., Kim, J. E., Park, C. G., Kim, H. J. & Lee, D. H., Aug 2024, In: World Allergy Organization Journal. 17, 8, 100949.

Research output: Contribution to journal › Article › peer-review

Open Access

Radioembolization plus Immune Checkpoint Inhibitor Therapy Compared with Radioembolization plus Tyrosine Kinase Inhibitor Therapy for the Treatment of Hepatocellular Carcinoma

Garcia-Reyes, K., Gottlieb, R. A., Menon, K. M., Bishay, V., Patel, R., Patel, R., Nowakowski, S., Sung, M. W., Marron, T. U., Gansa, W. H., Zhang, J., Raja, S. C., Shilo, D., Fischman, A., Lookstein, R. & Kim, E., May 2024, In: Journal of Vascular and Interventional Radiology. 35, 5, p. 722-730.e1

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Safety and efficacy outcomes of early cessation of anti-PD1 therapy in patients 80 years or older: A retrospective cohort study

Fletcher, K., Cortellini, A., Ganta, T., Kankaria, R., Song, H., Ye, F., Irlmeier, R., Debnath, N., Saeed, A., Radford, M., Alahmadi, A., Diamond, A., Hoimes, C., Presley, C. J., Owen, D. H., Abou Alaiwi, S., Nassar, A. H., Lamberti, G., Perrone, F. & Buti, S. & 17 others, Giusti, R., Filetti, M., Vanella, V., Mallardo, D., Sussman, T. A., Galetta, D., Kalofonou, F., Daniels, E., Ascierto, P. A., Pinato, D. J., Nebhan, C., Berg, S., Choueiri, T. K., Marron, T. U., Wang, Y., Naqash, A. R. & Johnson, D. B., 1 Aug 2024, In: Cancer Letters. 596, 217001.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Tumor-Immune Signatures of Treatment Resistance to Brentuximab Vedotin with Ipilimumab and/or Nivolumab in

Gonzalez-Kozlova, E., Huang, H. H., Jagede, O. A., Tuballes, K., Del Valle, D. M., Kelly, G., Patel, M., Xie, H., Harris, J., Argueta, K., Nie, K., Barcessat, V., Moravec, R., Altreuter, J., Duose, D. Y., Kahl, B. S., Ansell, S. M., Yu, J., Cerami, E. & Lindsay, J. R. & 4 others, Wistuba, I. I., Kim-Schulze, S., Diefenbach, C. S. & Gnjatic, S., Jul 2024, In: Cancer research communications. 4, 7, p. 1726-1737 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

A methylation clock model of mild SARS-CoV-2 infection provides insight into immune dysregulation

Biobank Team, 2023, (Accepted/In press) In: Molecular Systems Biology.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Anti-Integrin αvβ6 Autoantibodies Are a Novel Biomarker That Antedate Ulcerative Colitis

CCC-GEM Project Research Consortium & OSCCAR Consortium, Apr 2023, In: Gastroenterology. 164, 4, p. 619-629 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Antitumor immunity as the basis for durable disease-free treatment-free survival in patients with metastatic urothelial cancer

Anker, J., Pal, S. K., Kim-Schulze, S., Wang, H., Halperin, R., Uzilov, A., Imai, N., Eikawa, S., Saito, T., Sebra, R., Hahn, N. M., Patel, M., Qi, J., Xie, H., Bhardwaj, N., Gnjatic, S. & Galsky, M. D., 22 Aug 2023, In: Journal for ImmunoTherapy of Cancer. 11, 8, e007613.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression

Chen, Z., Giotti, B., Kaluzova, M., Vallcorba, M. P., Rawat, K., Price, G., Herting, C. J., Pinero, G., Cristea, S., Ross, J. L., Ackley, J., Maximov, V., Szulzewsky, F., Thomason, W., Marquez-Ropero, M., Angione, A., Nichols, N., Tsankova, N. M., Michor, F. & Shayakhmetov, D. M. & 3 others, Gutmann, D. H., Tsankov, A. M. & Hambardzumyan, D., 21 Sep 2023, In: Journal of Clinical Investigation. 133, 22, e163802.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

A Phase I Trial of VEGF-A Inhibition Combined with PD-L1 Blockade for Recurrent Glioblastoma

Chiu, D., Qi, J., Thin, T. H., Garcia-Barros, M., Lee, B., Hahn, M., Mandeli, J., Belani, P., Nael, K., Rashidipour, O., Ghatan, S., Hadjipanayis, C. G., Yong, R. L., Germano, I. M., Brody, R., Tsankova, N. M., Gnjatic, S., Kim-Schulze, S. & Hormigo, A., Jan 2023, In: Cancer research communications. 3, 1, p. 130-139 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Autoimmunity in Down’s syndrome via cytokines, CD4 T cells and CD11c⁺ B cells

Malle, L., Patel, R. S., Martin-Fernandez, M., Stewart, O. J., Philippot, Q., Buta, S., Richardson, A., Barcessat, V., Taft, J., Bastard, P., Samuels, J., Mircher, C., Rebillat, A. S., Maillebouis, L., Vilaire-Meunier, M., Tuballes, K., Rosenberg, B. R., Trachtman, R., Casanova, J. L. & Notarangelo, L. D. & 3 others, Gnjatic, S., Bush, D. & Bogunovic, D., 9 Mar 2023, In: Nature. 615, 7951, p. 305-314 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

Autonomic Neuropathy is Associated with More Densely Interconnected Cytokine Networks in People with HIV

Lawrence, S., Mueller, B. R., Benn, E. K. T., Kim-Schulze, S., Kwon, P. & Robinson-Papp, J., Dec 2023, In: Journal of NeuroImmune Pharmacology. 18, 4, p. 563-572 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Baseline neutrophil-lymphocyte ratio and platelet-lymphocyte ratio appear predictive of immune treatment related toxicity in hepatocellular carcinoma

Dharmapuri, S., Özbek, U., Jethra, H., Jun, T., Marron, T. U., Saeed, A., Huang, Y. H., Muzaffar, M., Pinter, M., Balcar, L., Fulgenzi, C., Amara, S., Weinmann, A., Personeni, N., Scheiner, B., Pressiani, T., Navaid, M., Bengsch, B., Paul, S. & Khan, U. & 17 others, Bettinger, D., Nishida, N., Mohamed, Y. I., Vogel, A., Gampa, A., Korolewicz, J., Cammarota, A., Kaseb, A., Galle, P. R., Pillai, A., Wang, Y. H., Cortellini, A., Kudo, M., D’Alessio, A., Rimassa, L., Pinato, D. J. & Ang, C., 2023, In: World Journal of Gastrointestinal Oncology. 15, 11, p. 1900-1912 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Circulating proteins to predict COVID-19 severity

The Mount Sinai COVID-19 Biobank Team, Dec 2023, In: Scientific Reports. 13, 1, 6236.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Cross center single-cell RNA sequencing study of the immune microenvironment in rapid progressing multiple myeloma

Pilcher, W., Thomas, B. E., Bhasin, S. S., Jayasinghe, R. G., Yao, L., Gonzalez-Kozlova, E., Dasari, S., Kim-Schulze, S., Rahman, A., Patton, J., Fiala, M., Cheloni, G., Kourelis, T., Dhodapkar, M. V., Vij, R., Mehr, S., Hamilton, M., Cho, H. J., Auclair, D. & Avigan, D. E. & 4 others, Kumar, S. K., Gnjatic, S., Ding, L. & Bhasin, M., Dec 2023, In: npj Genomic Medicine. 8, 1, 3.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Evaluation of immunological responses to third COVID-19 vaccine among people treated with sphingosine receptor-1 modulators and anti-CD20 therapy

Katz Sand, I., Gnjatic, S., Krammer, F., Tuballes, K., Carreño, J. M., Satyanarayan, S., Filomena, S., Staker, E., Tcheou, J., Miller, A., Fabian, M., Safi, N., Nichols, J., Patel, J., Krieger, S., Tankou, S., Horng, S., Klineova, S., Beck, E. & Merad, M. & 1 others, Lublin, F., Feb 2023, In: Multiple Sclerosis and Related Disorders. 70, 104486.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

Gemcitabine and cisplatin plus nivolumab as organ-sparing treatment for muscle-invasive bladder cancer: a phase 2 trial

Galsky, M. D., Daneshmand, S., Izadmehr, S., Gonzalez-Kozlova, E., Chan, K. G., Lewis, S., Achkar, B. E., Dorff, T. B., Cetnar, J. P., Neil, B. O., D’Souza, A., Mamtani, R., Kyriakopoulos, C., Jun, T., Gogerly-Moragoda, M., Brody, R., Xie, H., Nie, K., Kelly, G. & Horwitz, A. & 19 others, Kinoshita, Y., Ellis, E., Nose, Y., Ioannou, G., Cabal, R., Haines, G. K., Wang, L., Mouw, K. W., Samstein, R. M., Mehrazin, R., Bhardwaj, N., Yu, M., Zhao, Q., Kim-Schulze, S., Sebra, R., Zhu, J., Gnjatic, S., Sfakianos, J. & Pal, S. K., Nov 2023, In: Nature Medicine. 29, 11, p. 2825-2834 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Generation of functional thymic organoids from human pluripotent stem cells

Ramos, S. A., Armitage, L. H., Morton, J. J., Alzofon, N., Handler, D., Kelly, G., Homann, D., Jimeno, A. & Russ, H. A., 11 Apr 2023, In: Stem Cell Reports. 18, 4, p. 829-840 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Germline rare deleterious variant load alters cancer risk, age of onset and tumor characteristics

Esai Selvan, M., Onel, K., Gnjatic, S., Klein, R. J. & Gümüş, Z. H., Dec 2023, In: npj Precision Oncology. 7, 1, 13.

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Open Access

5 Scopus citations

Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression

Sattiraju, A., Kang, S., Giotti, B., Chen, Z., Marallano, V. J., Brusco, C., Ramakrishnan, A., Shen, L., Tsankov, A. M., Hambardzumyan, D., Friedel, R. H. & Zou, H., 8 Aug 2023, In: Immunity. 56, 8, p. 1825-1843.e6

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Open Access

46 Scopus citations

IgG memory B cells expressing IL4R and FCER2 are associated with atopic diseases

Aranda, C. J., Gonzalez-Kozlova, E., Saunders, S. P., Fernandes-Braga, W., Ota, M., Narayanan, S., He, J. S., Del Duca, E., Swaroop, B., Gnjatic, S., Shattner, G., Reibman, J., Soter, N. A., Guttman-Yassky, E. & Curotto de Lafaille, M. A., Mar 2023, In: Allergy: European Journal of Allergy and Clinical Immunology. 78, 3, p. 752-766 15 p.

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18 Scopus citations

Immunophenotypic correlates of sustained MRD negativity in patients with multiple myeloma

Coffey, D. G., Maura, F., Gonzalez-Kozlova, E., Diaz-Mejia, J. J., Luo, P., Zhang, Y., Xu, Y., Warren, E. H., Dawson, T., Lee, B., Xie, H., Smith, E., Ciardiello, A., Cho, H. J., Rahman, A., Kim-Schulze, S., Diamond, B., Lesokhin, A., Kazandjian, D. & Pugh, T. J. & 3 others, Green, D. J., Gnjatic, S. & Landgren, O., Dec 2023, In: Nature Communications. 14, 1, 5335.

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Open Access

10 Scopus citations

Impact of body mass index in patients receiving atezolizumab plus bevacizumab for hepatocellular carcinoma

Vithayathil, M., D’Alessio, A., Fulgenzi, C. A. M., Nishida, N., Schönlein, M., von Felden, J., Schulze, K., Wege, H., Saeed, A., Wietharn, B., Hildebrand, H., Wu, L., Ang, C., Marron, T. U., Weinmann, A., Galle, P. R., Bettinger, D., Bengsch, B., Vogel, A. & Balcar, L. & 15 others, Scheiner, B., Lee, P. C., Huang, Y. H., Amara, S., Muzaffar, M., Naqash, A. R., Cammarota, A., Zanuso, V., Pressiani, T., Pinter, M., Cortellini, A., Kudo, M., Rimassa, L., Pinato, D. J. & Sharma, R., Aug 2023, In: Hepatology International. 17, 4, p. 904-914 11 p.

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Open Access

13 Scopus citations

Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis

Kiss, M. G., Mindur, J. E., Yates, A. G., Lee, D., Fullard, J. F., Anzai, A., Poller, W. C., Christie, K. A., Iwamoto, Y., Roudko, V., Downey, J., Chan, C. T., Huynh, P., Janssen, H., Ntranos, A., Hoffmann, J. D., Jacob, W., Goswami, S., Singh, S. & Leppert, D. & 8 others, Kuhle, J., Kim-Schulze, S., Nahrendorf, M., Kleinstiver, B. P., Probert, F., Roussos, P., Swirski, F. K. & McAlpine, C. S., 11 Jul 2023, In: Immunity. 56, 7, p. 1502-1514.e8

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Open Access

9 Scopus citations

Intratumoral dendritic cell–CD4⁺ T helper cell niches enable CD8⁺ T cell differentiation following PD-1 blockade in hepatocellular carcinoma

Magen, A., Hamon, P., Fiaschi, N., Soong, B. Y., Park, M. D., Mattiuz, R., Humblin, E., Troncoso, L., D’souza, D., Dawson, T., Kim, J., Hamel, S., Buckup, M., Chang, C., Tabachnikova, A., Schwartz, H., Malissen, N., Lavin, Y., Soares-Schanoski, A. & Giotti, B. & 33 others, Hegde, S., Ioannou, G., Gonzalez-Kozlova, E., Hennequin, C., Le Berichel, J., Zhao, Z., Ward, S. C., Fiel, I., Kou, B., Dobosz, M., Li, L., Adler, C., Ni, M., Wei, Y., Wang, W., Atwal, G. S., Kundu, K., Cygan, K. J., Tsankov, A. M., Rahman, A., Price, C., Fernandez, N., He, J., Gupta, N. T., Kim-Schulze, S., Gnjatic, S., Kenigsberg, E., Deering, R. P., Schwartz, M., Marron, T. U., Thurston, G., Kamphorst, A. O. & Merad, M., Jun 2023, In: Nature Medicine. 29, 6, p. 1389-1399 11 p.

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Open Access

70 Scopus citations

Mechanisms of response and resistance to combined decitabine and ipilimumab for advanced myeloid disease

Penter, L., Liu, Y., Wolff, J. O., Yang, L., Taing, L., Jhaveri, A., Southard, J., Patel, M., Cullen, N. M., Pfaff, K. L., Cieri, N., Oliveira, G., Kim-Schulze, S., Ranasinghe, S., Leonard, R., Robertson, T., Morgan, E. A., Chen, H. X., Song, M. H. & Thurin, M. & 17 others, Li, S., Rodig, S. J., Cibulskis, C., Gabriel, S., Bachireddy, P., Ritz, J., Streicher, H., Neuberg, D. S., Hodi, F. S., Davids, M. S., Gnjatic, S., Livak, K. J., Altreuter, J., Michor, F., Soiffer, R. J., Garcia, J. S. & Wu, C. J., 13 Apr 2023, In: Blood. 141, 15, p. 1817-1830 14 p.

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Open Access

25 Scopus citations

Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae

The Mount Sinai COVID-19 Biobank Team, 1 Jan 2023, In: Nature Medicine. 29, 1, p. 236-246 11 p.

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Open Access

26 Scopus citations

Monocyte depletion enhances neutrophil influx and proneural to mesenchymal transition in glioblastoma

Chen, Z., Soni, N., Pinero, G., Giotti, B., Eddins, D. J., Lindblad, K. E., Ross, J. L., Puigdelloses Vallcorba, M., Joshi, T., Angione, A., Thomason, W., Keane, A., Tsankova, N. M., Gutmann, D. H., Lira, S. A., Lujambio, A., Ghosn, E. E. B., Tsankov, A. M. & Hambardzumyan, D., Dec 2023, In: Nature Communications. 14, 1, 1839.

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Open Access

16 Scopus citations

Human Immune Monitoring Center

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