Depression and Anxiety Center

Research output

Research output per year 1976 2014 2015 2018 2019 2020 2021 2022 2023

• 91712 Citations
• 156 h-index
• 800 Article
• 143 Review article
• 77 Comment/debate
• 42 Letter
• 74 More
  • 41 Chapter
  • 19 Editorial
  • 8 Short survey
  • 3 Book
  • 2 Conference contribution
  • 1 Foreword/postscript

Research output per year

Research output per year

Search results

• 2022

  Pharmacological Treatments for Anhedonia

  Klein, M. E., Grice, A. B., Sheth, S., Go, M. & Murrough, J. W., 2022, Current Topics in Behavioral Neurosciences. Springer Science and Business Media Deutschland GmbH, p. 467-490 24 p. (Current Topics in Behavioral Neurosciences; vol. 58).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Anhedonia 100%
  • Pharmacology 50%
  • Hallucinogens 34%
  • kappa Opioid Receptor 32%
  • Pleasure 29%
• 2021

  Connectomic DBS in major depression

  Choi, K. S. & Mayberg, H., 1 Jan 2021, Connectomic Deep Brain Stimulation. Elsevier, p. 433-447 15 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Connectome 100%
  • Deep Brain Stimulation 82%
  • Depression 46%
  • Treatment-Resistant Depressive Disorder 38%
  • Gyrus Cinguli 29%

• Drug-activated cells: From immediate early genes to neuronal ensembles in addiction

  Salery, M., Godino, A. & Nestler, E. J., Jan 2021, A Tribute to Paul Greengard (1925-2019). Zorn, S. H. (ed.). Academic Press Inc., p. 173-216 44 p. (Advances in Pharmacology; vol. 90).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Immediate-Early Genes 100%
  • Pharmaceutical Preparations 33%
  • Neurons 8%
  • Population 8%
  • Reward 6%
  5 Scopus citations

• Electrical deep neuromodulation in psychiatry

  Polosan, M. & Figee, M., Jan 2021, Emerging Horizons in Neuromodulation: New Frontiers in Brain and Spine Stimulation. Moro, E., Polosan, M. & Hamani, C. (eds.). Academic Press Inc., p. 89-110 22 p. (International Review of Neurobiology; vol. 159).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Deep Brain Stimulation 100%
  • Psychiatry 63%
  • Mental Disorders 34%
  • Brain 28%
  • Obsessive-Compulsive Disorder 15%
• 2020

  Chronic stress pathology and ketamine-induced alterations in functional connectivity in major depressive disorder: An abridged review of the clinical evidence

  Averill, L. A., Fouda, S., Murrough, J. W. & Abdallah, C. G., 2020, Rapid Acting Antidepressants. Duman, R. S. & Krystal, J. H. (eds.). Academic Press Inc., p. 163-194 32 p. (Advances in Pharmacology; vol. 89).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Ketamine 100%
  • Major Depressive Disorder 94%
  • Pathology 57%
  • Antidepressive Agents 40%
  • Treatment-Resistant Depressive Disorder 15%
  6 Scopus citations

• Cognitive and behavioral components of resilience to stress

  Iacoviello, B. M. & Charney, D. S., 1 Jan 2020, Stress Resilience: Molecular and Behavioral Aspects. Elsevier, p. 23-31 9 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Psychology 100%
  • Optimism 88%
  • Psychological Adaptation 84%
  • Social Networking 83%
  • Literature 78%
  7 Scopus citations

• The emergence of ketamine as a novel treatment for posttraumatic stress disorder

  Feder, A., Rutter, S. B., Schiller, D. & Charney, D. S., 2020, Rapid Acting Antidepressants. Duman, R. S. & Krystal, J. H. (eds.). Academic Press Inc., p. 261-286 26 p. (Advances in Pharmacology; vol. 89).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Ketamine 100%
  • Post-Traumatic Stress Disorders 89%
  • Fear 15%
  • Therapeutics 14%
  • Treatment-Resistant Depressive Disorder 12%
  25 Scopus citations
• 2019

  Cingulate-mediated depressive symptoms in neurologic disease and therapeutics

  Riva-Posse, P., Holtzheimer, P. E. & Mayberg, H. S., 2019, Handbook of Clinical Neurology. Elsevier B.V., p. 371-379 9 p. (Handbook of Clinical Neurology; vol. 166).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Gyrus Cinguli 100%
  • Nervous System Diseases 90%
  • Depression 63%
  • Deep Brain Stimulation 37%
  • Neurosciences 34%
  7 Scopus citations

• Molecular, cellular, and circuit basis of depression susceptibility and resilience

  Han, M. H., Russo, S. J. & Nestler, E. J., 1 Jan 2019, Neurobiology of Depression: Road to Novel Therapeutics. Elsevier, p. 123-136 14 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Depression 100%
  • Psychological Resilience 60%
  • Major Depressive Disorder 39%
  • Epigenomics 33%
  • Therapeutics 24%
  9 Scopus citations

• Molecular characterization of the resilient brain: Transcriptional and epigenetic mechanisms. transcriptional and epigenetic mechanisms.

  Issler, O., Lorsch, Z. S. & Nestler, E. J., 1 Nov 2019, Stress Resilience: Molecular and Behavioral Aspects. Elsevier, p. 209-231 23 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Mental Disorders 100%
  • Brain 60%
  • Epigenomics 53%
  • Direction compound 44%
  • Animal Models 44%
  2 Scopus citations

• Neurocognitive Basis of Compulsivity

  Figee, M., Luigjes, J., Goudriaan, A., Willuhn, I. & Denys, D., 1 Jan 2019, A Transdiagnostic Approach to Obsessions, Compulsions and Related Phenomena. Cambridge University Press, p. 61-73 13 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  2 Scopus citations

• The genetic architecture of bipolar disorder: Entering the road of discoveries

  Smeland, O. B., Forstner, A. J., Charney, A., Stahl, E. A. & Andreassen, O. A., 1 Jan 2019, Personalized Psychiatry. Elsevier, p. 215-225 11 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Bipolar Disorder 100%
  • Genetic Loci 15%
  • Molecular Epidemiology 15%
  • Treatment Adherence and Compliance 14%
  • Precision Medicine 13%
• 2018

  Neuroepigenetic editing

  Hamilton, P. J., Lim, C. J., Nestler, E. J. & Heller, E. A., 2018, Methods in Molecular Biology. Humana Press Inc., p. 113-136 24 p. (Methods in Molecular Biology; vol. 1767).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Chromatin 100%
  • Therapeutic Human Experimentation 76%
  • Animal Behavior 73%
  • Gene Expression Regulation 60%
  • Neurosciences 60%
  16 Scopus citations

• Neuroepigenetics and addiction

  Walker, D. M. & Nestler, E. J., 2018, Neurogenetics, Part II. Geschwind, D. H., Paulson, H. L. & Klein, C. (eds.). Elsevier B.V., p. 747-765 19 p. (Handbook of Clinical Neurology; vol. 148).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Substance-Related Disorders 100%
  • Epigenomics 99%
  • Reward 73%
  • Animal Models 54%
  • Brain 37%
  62 Scopus citations

• Progress in Epigenetics of Depression

  Peña, C. J. & Nestler, E. J., 2018, Progress in Molecular Biology and Translational Science. Elsevier B.V., p. 41-66 26 p. (Progress in Molecular Biology and Translational Science; vol. 157).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Epigenomics 100%
  • Depression 75%
  • Histone Code 16%
  • Untranslated RNA 16%
  • Risk-Taking 14%
  46 Scopus citations

• Stereotaxic surgery and viral delivery of zinc-finger epigenetic editing tools in rodent brain

  Hamilton, P. J., Lim, C. J., Nestler, E. J. & Heller, E. A., 2018, Methods in Molecular Biology. Humana Press Inc., p. 229-238 10 p. (Methods in Molecular Biology; vol. 1867).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Zinc Fingers 100%
  • Epigenomics 77%
  • Rodentia 73%
  • Brain 43%
  • Stereotaxic Techniques 34%
  2 Scopus citations

• Viral expression of epigenome editing tools in rodent brain using stereotaxic surgery techniques

  Hamilton, P. J., Lim, C. J., Nestler, E. J. & Heller, E. A., 2018, Methods in Molecular Biology. Humana Press Inc., p. 205-214 10 p. (Methods in Molecular Biology; vol. 1767).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Stereotaxic Techniques 100%
  • Epigenome 80%
  • Rodentia 53%
  • Brain 31%
  • Dependovirus 19%
  5 Scopus citations
• 2017

  Drug repositioning opportunities in psychiatry

  Charney, A. W., Scarpa, J. R., Ruderfer, D. M. & Charney, D. S., 1 Jan 2017, Drug Repositioning: Approaches and Applications for Neurotherapeutics. CRC Press, p. 241-252 12 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Drug Repositioning 100%
  • Bipolar Disorder 70%
  • Neurotransmitter Agents 63%
  • Disorder 62%
  • Psychiatry 54%

• Epigenetic Modifications of DNA and Drug Addiction

  Feng, J. & Nestler, E. J., 5 Jan 2017, DNA Modifications in the Brain: Neuroepigenetic Regulation of Gene Expression. Elsevier Inc., p. 127-147 21 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Substance-Related Disorders 100%
  • Epigenomics 99%
  • DNA 63%
  • Dioxygenases 27%
  • Methyltransferases 21%
  1 Scopus citations

• Optogenetics and the dissection of neural circuits underlying depression and substance-use disorders

  Juarez, B., Friedman, A. K. & Han, M. H., 1 Jan 2017, Optogenetics: From Neuronal Function to Mapping and Disease Biology. Cambridge University Press, p. 257-275 19 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Optogenetics 100%
  • Substance-Related Disorders 67%
  • Dissection 66%
  • Disorder 65%
  • Major Depressive Disorder 60%
• 2016

  An assessment of the catecholamine hypothesis of bipolar disorder

  Charney, A. W., Sayed, S. & Charney, D. S., 1 Jan 2016, Bipolar Disorders: Basic Mechanisms and Therapeutic Implications, Third Edition. Cambridge University Press, p. 21-42 22 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Bipolar Disorder 100%
  • Catecholamines 96%
  • Epinephrine 19%
  • sorbitan monostearate 16%
  • ferric chloride 16%
  1 Scopus citations

• Ketamine’s mechanism of rapid antidepressant activity: Evidence gleaned from clinical studies

  Averill, L. A., Murrough, J. W. & Abdallah, C. G., 1 Jan 2016, Ketamine for Treatment-Resistant Depression: The First Decade of Progress. Springer International Publishing, p. 99-121 23 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Ketamine 100%
  • Antidepressive Agents 81%
  • Drug Development 64%
  • Clinical Studies 63%
  • Neurobiology 53%
  5 Scopus citations

• Neuroepigenomics and Human Disease

  Greally, J. M. & Nestler, E. J., 21 Jun 2016, Genomics, Circuits, and Pathways in Clinical Neuropsychiatry. Elsevier Inc., p. 73-91 19 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Epigenomics 100%
  • Genetic Epigenesis 54%
  • Explosive Agents 48%
  • Nervous System 31%
  • Mental Disorders 30%
• 2014

  From neurobiology to treatment: Progress against addiction

  Nestler, E. J., 14 May 2014, The ASAM Principles of Addiction Medicine: Fifth Edition. Wolters Kluwer Health Adis (ESP)

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• 2013

  An Overview of the Molecular Basis of Epigenetics

  Sweatt, J. D., Nestler, E. J., Meaney, M. J. & Akbarian, S., 2013, Epigenetic Regulation in the Nervous System. Elsevier Inc., p. 3-33 31 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  10 Scopus citations

• Drug Addiction and Reward

  Robison, A. J., Feng, J. & Nestler, E. J., 2013, Epigenetic Regulation in the Nervous System. Elsevier Inc., p. 173-195 23 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  2 Scopus citations

• Epigenetics. Defining the Frontiers of Genomic Function

  Meaney, M. J., Akbarian, S., Nestler, E. J. & Sweatt, J. D., 2013, Epigenetic Regulation in the Nervous System. Elsevier Inc., p. 341-353 13 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  1 Scopus citations

• What Can Fear and Reward Learning Teach Us About Depression?

  Collins, K. A. & Schiller, D., 2013, Behavioral Neurobiology of Depression and Its Treatment. Cowen, P. J., Lau, J. Y. F. & Sharp, T. (eds.). p. 223-242 20 p. (Current Topics in Behavioral Neurosciences; vol. 14).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Major Depressive Disorder 100%
  • Reward 92%
  • Fear 84%
  • Learning 70%
  • Depression 63%
  3 Scopus citations
• 2011

  Animal models of depression: Molecular perspectives

  Krishnan, V. & Nestler, E. J., 2011, Molecular and Functional Models in NeuropsychiatrY. Hagan, J. J. (ed.). 1 ed. p. 121-147 27 p. (Current Topics in Behavioral Neurosciences; vol. 7, no. 1).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Animal Models 100%
  • Depression 90%
  • Genetic Models 22%
  • Antidepressive Agents 17%
  • Molecular Biology 16%
  333 Scopus citations

• Anxiety disorders

  Murrough, J. W., Mathew, S. J. & Charney, D. S., 3 Nov 2011, Clinical Psychiatry Essentials. Wolters Kluwer Health, p. 207-224 18 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

• Cyclic Nucleotides in the Nervous System

  Pittenger, C., Nestler, E. J. & Duman, R. S., 7 Dec 2011, Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology: Eighth Edition. Elsevier, p. 423-441 19 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
  6 Scopus citations

• Neurobiology of resilience

  Feder, A., Charney, D. & Collins, K., 1 Jan 2011, Resilience and Mental Health: Challenges Across the Lifespan. Cambridge University Press, p. 1-29 29 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Neurobiology 100%
  • Survivors 75%
  • Cyclonic Storms 61%
  • Physiological Stress 51%
  • Poverty 46%
  30 Scopus citations

• Targeted modulation of neural circuits: A new treatment strategy for neuropsychiatric disease

  Mayberg, H. S. & Holtzheimer, P. E., 2011, Electrophysiological Recording Techniques. Vertes, R. & Stackman, Jr., R. (eds.). p. 257-279 23 p. (Neuromethods; vol. 54).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Disorder 100%
  • Deep Brain Stimulation 90%
  • Developmental 70%
  • Psychological Theory 56%
  • Wells syndrome 54%
• 2010

  Molecular Neurobiology of Addiction

  Nestler, E. J., 1 Jan 2010, Encyclopedia of Behavioral Neuroscience. Elsevier Inc., p. 250-256 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Neurobiology 100%
  • Substance-Related Disorders 50%
  • Brain 42%
  • Gene Expression 34%
  • Reward 27%
  1 Scopus citations

• Neurobiological factors underlying psychosocial moderators of childhood stress and trauma

  Ozbay, F., Sharma, V., Kaufman, J., McEwen, B., Charney, D. & Southwick, S., 1 Jan 2010, The Impact of Early Life Trauma on Health and Disease: The Hidden Epidemic. Cambridge University Press, p. 189-199 11 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Gene-Environment Interaction 100%
  • Social Support 77%
  • Information Theory 59%
  • Neurochemistry 54%
  • Psychology 54%
  3 Scopus citations

• Overcoming antidepressant treatment resistance: Focus on glutamate

  Murrough, J. W. & Mathew, S. J., 2010, Depression: From Psychopathology to Pharmacotherapy. Cryan, J. & Leonard, B. (eds.). p. 89-100 12 p. (Modern Trends in Pharmacopsychiatry; vol. 27).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Antidepressive Agents 100%
  • Glutamic Acid 97%
  • Ketamine 61%
  • Drug Discovery 38%
  • N-methylglutamate 28%
  1 Scopus citations
• 2009

  Panic Disorder

  Heuer, L. E., Mathew, S. J. & Charney, D. S., 2009, Encyclopedia of Neuroscience. Elsevier Ltd., p. 421-425 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Panic Disorder 100%
  • Agoraphobia 25%
  • Elevators and Escalators 13%
  • Neurobehavioral Manifestations 11%
  • Neurobiology 11%
• 2007

  Abnormalities in catecholamines and the pathophysiology of bipolar disorder

  Garakani, A., Charney, D. S. & Anand, A., 1 Jan 2007, Bipolar Disorders: Basic Mechanisms and Therapeutic Implications, Second Edition. CRC Press, p. 33-65 33 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Bipolar Disorder 100%
  • Catecholamines 96%
  • Neurosciences 13%
  • Single-Photon Emission-Computed Tomography 13%
  • Positron-Emission Tomography 12%
  2 Scopus citations

• Resilience and Vulnerability to Trauma

  Cooper, N. S., Feder, A., Southwick, S. M. & Charney, D. S., 22 Mar 2007, Adolescent Psychopathology and the Developing Brain: Integrating Brain and Prevention Science. Oxford University Press

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Brain 100%
  • Wounds and Injuries 98%
  1 Scopus citations
• 2006

  PTSD in urban primary care patients following 9/11

  Neria, Y., Gross, R., Olfson, M., Gameroff, M. J., Das, A., Feder, A., Lantigua, R., Shea, S. & Weissman, M. M., 1 Jan 2006, 9/11: Mental Health in the Wake of Terrorist Attacks. Cambridge University Press, p. 239-263 25 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Disasters 100%
  • Post-Traumatic Stress Disorders 86%
  • Primary Health Care 69%
  • Terrorism 54%
  • Natural Disasters 34%
  3 Scopus citations
• 2005

  Anxiety disorders: Noradrenergic neurotransmission

  Neumeister, A., Daher, R. J. & Charney, D. S., 2005, Anxiety and Anxiolytic Drugs. Springer Science and Business Media, LLC, p. 205-223 19 p. (Handbook of Experimental Pharmacology; vol. 169).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

  • Anxiety Disorders 100%
  • Synaptic Transmission 96%
  • Disorder 88%
  • Neuropeptides 42%
  • Fear 35%
  19 Scopus citations