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Collaborations and top research areas from the last five years
Profiles
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James Murrough
- BioMedical Engineering and Imaging Institute
- Brain-Body Center
- Center for Affective Neuroscience
- Depression and Anxiety Center
- Friedman Brain Institute
- Graduate School of Biomedical Sciences
- Icahn School of Medicine at Mount Sinai
- Mount Sinai Academy of Physician-Scientists
- Mount Sinai Institute for Systems Biomedicine
- Nash Family Center for Advanced Circuit Therapeutics
- Psychiatry
Person
Research output
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Advancing resilience science through cross-domain integration: Proceedings of an NIH workshop
Pasiakos, S. M., Bamman, M. M., Cook, S. H., DePierro, J. M., Haus, J. M., Lieberman, H. R., Litwa, K. A., McDermott, M. M., Taylor, H. A., Ungar, M. & Cohen, B. E., Jul 2026, In: Neuroscience and Biobehavioral Reviews. 186, 106660.Research output: Contribution to journal › Review article › peer-review
Open Access -
High obstructive sleep apnea hypoxic burden associates with reduced locus coeruleus structural integrity on 7T MRI in older adults
Kam, K., Gaggi, N. L., Parekh, A., Valencia, D. I., Quintana Licona, D. A., Hishinuma, S. S., Martillo, K. R., Chu, S. S., Varga, A. W., Hwang, J., Williams, M. K., Mullins, A. E., Tolbert, T. M., Balchandani, P., Iosifescu, D. V., Blessing, E. M., Bubu, O. M., Ayappa, I., Rapoport, D. M. & Morris, L. S. & 1 others, , 1 Mar 2026, In: Sleep. 49, 3, zsaf398.Research output: Contribution to journal › Article › peer-review
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High prevalence of pain and mental health conditions amongst people well-established in HIV care: results of a cross-sectional survey in Lima, Peru
Lasowski, P., Tollefson, D., Menacho, L., DePierro, J. & Duerr, A., 2026, In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. 38, 1, p. 162-171 10 p.Research output: Contribution to journal › Article › peer-review
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Hippocampal subfield-specific imaging in depression: the translational power of ultra-high field MRI
Jubeir, J. & Jacob, Y., Dec 2026, In: Translational Psychiatry. 16, 1, 78.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations -
KET-MCI: A Pilot Safety and Tolerability Study of Single Infusion Intravenous Ketamine for Older Adults with Depression and Mild Cognitive Impairment
Fremont, R., Karim, A., Estevez, T. P., McDonough, C., LaBarbiera, A., Feder, A., Naasan, G., Delgado, A., Charney, D. S. & Murrough, J. W., 2026, (Accepted/In press) In: American Journal of Geriatric Psychiatry.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Major depressive disorder shares systemic immune signatures and potential therapeutic targets with inflammatory skin diseases
He, H., Cathomas, F., Parise, L. F., David, E., Rizk, M., Hawkins, K., Karpman, E., Russo, S. J., Guttman, E. & Murrough, J. W., May 2026, In: Molecular Psychiatry. 31, 5, p. 2498-2508 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The Use of Vagus Nerve Stimulation (VNS) in the Management of Patients with Difficult-to-Treat Major Depressive Disorder (MDD): An Expert Consensus Statement
McAllister-Williams, R. H., Alva, G., Banov, M., Conway, C. R., Cusin, C., De Beer, J. C., Demyttenaere, K., Domany, Y., Domenech, P., Dougherty, D. D., Dunner, D. L., Feffer, K., George, M. S., Iosifescu, D. V., Kavakbasi, E., Kraus, C., Lehnhardt, F. G., Lesperance, P., McCall, W. V. & Murrough, J. W. & 13 others, , 2026, In: Neuropsychiatric Disease and Treatment. 22, 554007.Research output: Contribution to journal › Article › peer-review
Open Access -
Association of perceived leadership effectiveness and mental health symptoms in health system staff and faculty: a cross-sectional survey study
Khan, A., Delgado, A., Ali, H., Klepser, N., Buehler, N., Clark, U., Pietrzak, R., Depierro, J., Marin, D. B., Ripp, J. & Peccoralo, L., 2025, (Accepted/In press) In: BMJ Leader.Research output: Contribution to journal › Article › peer-review
Open Access -
Association of Psychological Resilience With Decelerated Brain Aging in Cognitively Healthy World Trade Center Responders
Seeley, S. H., Fremont, R., Schreiber, Z., Morris, L. S., Cahn, L., Murrough, J. W., Schiller, D., Charney, D. S., Pietrzak, R. H., Perez-Rodriguez, M. M. & Feder, A., Jul 2025, In: Biological Psychiatry Global Open Science. 5, 4, 100489.Research output: Contribution to journal › Article › peer-review
Open Access -
Azetukalner, a Novel KV7 Potassium Channel Opener, in Adults With Major Depressive Disorder: A Randomized Clinical Trial
Butterfield, N. N., Luzon Rosenblut, C., Fava, M., Correll, C. U., Rothschild, A. J., Murrough, J. W., Mathew, S. J., Beatch, G. N., Grayson, C., Harden, C., Qian, J., McIntosh, J., Namdari, R. & Kenney, C., May 2025, In: JAMA network open. 8, 5, e2514278.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cognitive arousal-based measures quantify insights from self-ratings in response to sensory stimuli
Oliver, S., Zhang, J., Raju, V., Murrough, J. W. & Faghih, R. T., Nov 2025, In: PLOS Mental Health. 2, 11 November, e0000463.Research output: Contribution to journal › Article › peer-review
Open Access -
Combining Ketamine Infusions and Written Exposure Therapy for Chronic PTSD: An Open-Label Trial
Feder, A., Brown, O., Rutter, S. B., Cahn, L., Overbey, J. R., Seeley, S. H., Yu, A., Bonanno, P. A., Fremont, R. A., Delgado, A. A., Jha, M. K., Costi, S., Yehuda, R., Schiller, D., Pietrzak, R. H., Charney, D. S., Sloan, D. M. & Murrough, J. W., Jun 2025, In: Journal of Clinical Psychiatry. 86, 2, 24m15622.Research output: Contribution to journal › Article › peer-review
4 Scopus citations
Press/Media
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Kv7 Channel Modulator Shows Promise for Anhedonia in MDD, With James Murrough, MD
16/04/26
1 item of Media coverage
Press/Media
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Researchers from Icahn School of Medicine at Mount Sinai Describe Findings in Major Depressive Disorder (Machine learning framework for depression subtype grouping: integrating high-resolution imaging and clinical symptom analysis via ...)
Verma, G., Jacob, Y., Murrough, J., Morris, L., Balchandani, P. & Delman, B.
16/04/26
1 item of Media coverage
Press/Media
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Reports Outline Drug Research Study Results from Rachel Fremont et al (KET-MCI: A Pilot Safety and Tolerability Study of Single Infusion Intravenous Ketamine for Older Adults with Depression and Mild Cognitive Impairment)
Delgado, A., Murrough, J., Naasan, G., Charney, D. & Feder, A.
13/04/26
1 item of Media coverage
Press/Media
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Kv7 Channel Modulator Azetukalner May Improve Anhedonia, With James Murrough, MD, PhD
9/04/26
1 item of Media coverage
Press/Media
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Reports from Northern Centre for Mood Disorders Advance Knowledge in Depression [The Use of Vagus Nerve Stimulation (VNS) in the Management of Patients with Difficult-to-Treat Major Depressive Disorder (MDD): An Expert Consensus Statement]
Iosifescu, D. V. & Murrough, J.
6/04/26
1 item of Media coverage
Press/Media
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Neutralizing Interleukin (IL)-6 Signaling to Reverse Immune Related Anhedonia in Patients With Major Depressive Disorder
3/04/26
1 item of Media coverage
Press/Media
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Major Depression Shares Immune Signature With Inflammatory Skin Ailments, Suggesting Novel Therapeutic Possibilities, Study Indicates
Cathomas, F., Rizk, M., Murrough, J., Russo, S. & Guttman, E.
2/04/26
1 item of Media coverage
Press/Media
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