Center for Inborn Errors of Immunity

2023

Advances and Challenges of the Decade: The Ever-Changing Clinical and Genetic Landscape of Immunodeficiency

Walter, J. E., Ziegler, J. B., Ballow, M. & Cunningham-Rundles, C., Jan 2023, In: Journal of Allergy and Clinical Immunology: In Practice. 11, 1, p. 107-115 9 p.

Research output: Contribution to journal › Article › peer-review

An anti-OX40 antibody to treat moderate-to-severe atopic dermatitis: a multicentre, double-blind, placebo-controlled phase 2b study

Guttman-Yassky, E., Simpson, E. L., Reich, K., Kabashima, K., Igawa, K., Suzuki, T., Mano, H., Matsui, T., Esfandiari, E. & Furue, M., 21 Jan 2023, In: The Lancet. 401, 10372, p. 204-214 11 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

A phase 2a randomized vehicle-controlled multi-center study of the safety and efficacy of delgocitinib in subjects with moderate-to-severe alopecia areata

Mikhaylov, D., Glickman, J. W., Del Duca, E., Nia, J., Hashim, P., Singer, G. K., Posligua, A. L., Florek, A. G., Ibler, E., Hagstrom, E. L., Estrada, Y., Rangel, S. M., Colavincenzo, M., Paller, A. S. & Guttman-Yassky, E., Mar 2023, In: Archives of Dermatological Research. 315, 2, p. 181-189 9 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Apremilast and narrowband ultraviolet B combination therapy suppresses Th17 axis and promotes melanogenesis in vitiligo skin: a randomized, split-body, pilot study in skin types IV–VI

Kim, H. J., Del Duca, E., Pavel, A. B., Singer, G. K., Abittan, B. J., Chima, M. A., Kimmel, G., Bares, J., Baum, D., Gagliotti, M., Genece, J., Chu, J., Lebwohl, M. G. & Guttman-Yassky, E., Mar 2023, In: Archives of Dermatological Research. 315, 2, p. 215-221 7 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Autoimmunity in Down’s syndrome via cytokines, CD4 T cells and CD11c⁺ B cells

Malle, L., Patel, R. S., Martin-Fernandez, M., Stewart, O. J., Philippot, Q., Buta, S., Richardson, A., Barcessat, V., Taft, J., Bastard, P., Samuels, J., Mircher, C., Rebillat, A. S., Maillebouis, L., Vilaire-Meunier, M., Tuballes, K., Rosenberg, B. R., Trachtman, R., Casanova, J. L., Notarangelo, L. D., & 3 othersGnjatic, S., Bush, D. & Bogunovic, D., 9 Mar 2023, In: Nature. 615, 7951, p. 305-314 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Autologous hematopoietic stem cell transplantation in Clarkson disease

Druey, K. M., Eisch, A. R. & Cunningham-Rundles, C., Jan 2023, In: Journal of Allergy and Clinical Immunology: In Practice. 11, 1, p. 347-349 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Delayed type hypersensitivity reactions to various allergens may differently model inflammatory skin diseases

Pavel, A. B., Del Duca, E., Cheng, J., Wu, J., Ungar, B., Estrada, Y. D., Jack, C., Maari, C., Proulx, É. S. C., Ramirez-Valle, F., Krueger, J. G., Bissonnette, R. & Guttman-Yassky, E., Jan 2023, In: Allergy: European Journal of Allergy and Clinical Immunology. 78, 1, p. 178-191 14 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Efficacy and safety of etrasimod, a sphingosine 1-phosphate receptor modulator, in adults with moderate-to-severe atopic dermatitis (ADVISE)

Silverberg, J. I., Bissonnette, R., Kircik, L., Murrell, D. F., Selfridge, A., Liu, K., Ahluwalia, G. & Guttman-Yassky, E., 2023, (Accepted/In press) In: Journal of the European Academy of Dermatology and Venereology.

Research output: Contribution to journal › Article › peer-review

Open Access

Evaluation and validation of an RT-PCR assay for specific detection of monkeypox virus (MPXV)

Paniz-Mondolfi, A., Guerra, S., Muñoz, M., Luna, N., Hernandez, M. M., Patino, L. H., Reidy, J., Banu, R., Shrestha, P., Liggayu, B., Umeaku, A., Chen, F., Cao, L., Patel, A., Hanna, A., Li, S., Look, A., Pagani, N., Albrecht, R., Pearl, R., & 24 othersGarcia-Sastre, A., Bogunovic, D., Palacios, G., Bonnier, L., Cera, F., Lopez, H., Calderon, Y., Eiting, E., Mullen, K., Shin, S. J., Lugo, L. A., Urbina, A. E., Starks, C., Koo, T., Uychiat, P., Look, A., van Bakel, H., Gonzalez-Reiche, A., Betancourt, A. F., Reich, D., Cordon-Cardo, C., Simon, V., Sordillo, E. M. & Ramírez, J. D., Jan 2023, In: Journal of Medical Virology. 95, 1, e28247.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Human IL-23 is essential for IFN-γ-dependent immunity to mycobacteria

Philippot, Q., Ogishi, M., Bohlen, J., Puchan, J., Arias, A. A., Nguyen, T., Martin-Fernandez, M., Conil, C., Rinchai, D., Momenilandi, M., Mahdaviani, S. A., Keramatipour, M., Rosain, J., Yang, R., Khan, T., Neehus, A. L., Materna, M., Han, J. E., Peel, J., Mele, F., & 38 othersWeisshaar, M., Jovic, S., Bastard, P., Lévy, R., Le Voyer, T., Zhang, P., Maglorius Renkilaraj, M. R. L., Arango-Franco, C. A., Pelham, S., Seeleuthner, Y., Pochon, M., Ata, M. M. A., Al Ali, F., Migaud, M., Soudée, C., Kochetkov, T., Molitor, A., Carapito, R., Bahram, S., Boisson, B., Fieschi, C., Mansouri, D., Marr, N., Okada, S., Shahrooei, M., Parvaneh, N., Chavoshzadeh, Z., Cobat, A., Bogunovic, D., Abel, L., Tangye, S. G., Ma, C. S., Béziat, V., Sallusto, F., Boisson-Dupuis, S., Bustamante, J., Casanova, J. L. & Puel, A., 17 Feb 2023, In: Science immunology. 8, 80, p. eabq5204

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Identifying shared genetic factors underlying epilepsy and congenital heart disease in Europeans

Wu, Y., Bayrak, C. S., Dong, B., He, S., Stenson, P. D., Cooper, D. N., Itan, Y. & Chen, L., Feb 2023, In: Human Genetics. 142, 2, p. 275-288 14 p.

Research output: Contribution to journal › Article › peer-review

Impact of vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on the atopic dermatitis serum proteome

Kim, M., Ungar, B., Estrada, Y., Pavel, A. B. & Guttman-Yassky, E., Mar 2023, In: Annals of Allergy, Asthma and Immunology. 130, 3, p. 355-358 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children

CoV-Contact Cohort & COVID Human Genetic Effort, 10 Feb 2023, In: Science. 379, 6632, eabo3627.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae

The Mount Sinai COVID-19 Biobank Team, Jan 2023, In: Nature Medicine. 29, 1, p. 236-246 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

No association between dupilumab use and short-term cancer development in atopic dermatitis patients

Owji, S., Ungar, B., Dubin, D. P., Poplausky, D., Young, J. N., Ghalili, S., Han, J., Srinivasan, D., Packer, S., Pavel, A. B., Correa da Rosa, J., Guttman-Yassky, E. & Gulati, N., 2023, (Accepted/In press) In: Journal of Allergy and Clinical Immunology: In Practice.

Research output: Contribution to journal › Article › peer-review

Proteomic characterization of atopic dermatitis blood from infancy to adulthood

Del Duca, E., Renert-Yuval, Y., Pavel, A. B., Mikhaylov, D., Wu, J., Lefferdink, R., Fang, M., Sheth, A., Blumstein, A., Facheris, P., Estrada, Y. D., Rangel, S. M., Krueger, J. G., Paller, A. S. & Guttman-Yassky, E., 2023, (Accepted/In press) In: Journal of the American Academy of Dermatology.

Research output: Contribution to journal › Article › peer-review

Safety of upadacitinib in moderate-to-severe atopic dermatitis: An integrated analysis of phase 3 studies

Guttman-Yassky, E., Thyssen, J. P., Silverberg, J. I., Papp, K. A., Paller, A. S., Weidinger, S., Chih-ho Hong, H., Hendrickson, B., Dilley, D., Tenorio, A. R., Ladizinski, B., Chu, A. D., Liu, J. & Irvine, A. D., Jan 2023, In: Journal of Allergy and Clinical Immunology. 151, 1, p. 172-181 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Safety profile of upadacitinib over 15 000 patient-years across rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and atopic dermatitis

Burmester, G. R., Cohen, S. B., Winthrop, K. L., Nash, P., Irvine, A. D., Deodhar, A., Mysler, E., Tanaka, Y., Liu, J., Lacerda, A. P., Palac, H., Shaw, T., Mease, P. J. & Guttman Yassky, E., 8 Feb 2023, In: RMD Open. 9, 1, e002735.

Research output: Contribution to journal › Article › peer-review

Open Access

Secukinumab responses vary across the spectrum of congenital ichthyosis in adults

Lefferdink, R., Rangel, S. M., Chima, M., Ibler, E., Pavel, A. B., Kim, H. J., Wu, B., Abu-Zayed, H., Wu, J., Jackson, K., Singer, G., Choate, K. A., Guttman-Yassky, E. & Paller, A. S., Mar 2023, In: Archives of Dermatological Research. 315, 2, p. 305-315 11 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Skin TARC/CCL17 increase precedes the development of childhood atopic dermatitis

Halling, A. S., Rinnov, M. R., Ruge, I. F., Gerner, T., Ravn, N. H., Knudgaard, M. H., Trautner, S., Loft, N., Skov, L., Thomsen, S. F., Egeberg, A., Guttman-Yassky, E., Rosted, A. L. L., Petersen, T., Jakasa, I., Kezic, S. & Thyssen, J. P., 2023, (Accepted/In press) In: Journal of Allergy and Clinical Immunology.

Research output: Contribution to journal › Article › peer-review

Open Access

Spesolimab, an anti-interleukin-36 receptor antibody, in patients with moderate-to-severe atopic dermatitis: Results from a multicentre, randomized, double-blind, placebo-controlled, phase IIa study

Bissonnette, R., Abramovits, W., Saint-Cyr Proulx, É., Lee, P., Guttman-Yassky, E., Zovko, E., Sigmund, R., Willcox, J. & Bieber, T., Mar 2023, In: Journal of the European Academy of Dermatology and Venereology. 37, 3, p. 549-557 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2022

Analysis of alopecia areata surveys suggests a threshold for improved patient-reported outcomes

Renert-Yuval, Y., Correa da Rosa, J., Garcet, S., Pavel, A. B., Bares, J., Chima, M., Hawkes, J. E., Gilleaudeau, P., Sullivan-Whalen, M., Singer, G. K., Krueger, J. G. & Guttman-Yassky, E., Oct 2022, In: British Journal of Dermatology. 187, 4, p. 539-547 9 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

A partial form of inherited human USP18 deficiency underlies infection and inflammation

Martin-Fernandez, M., Buta, S., Le Voyer, T., Li, Z., Dynesen, L. T., Vuillier, F., Franklin, L., Ailal, F., Amancio, A. M., Malle, L., Gruber, C., Benhsaien, I., Altman, J., Taft, J., Deswarte, C., Roynard, M., Nieto-Patlan, A., Moriya, K., Rosain, J., Boddaert, N., & 8 othersBousfiha, A., Crow, Y. J., Jankovic, D., Sher, A., Casanova, J. L., Pellegrini, S., Bustamante, J. & Bogunovic, D., 4 Apr 2022, In: Journal of Experimental Medicine. 219, 4, e20211273.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

A shift in lung macrophage composition is associated with COVID-19 severity and recovery

Chen, S. T., Park, M. D., Del Valle, D. M., Buckup, M., Tabachnikova, A., Thompson, R. C., Simons, N. W., Mouskas, K., Lee, B., Geanon, D., D'Souza, D., Dawson, T., Marvin, R., Nie, K., Zhao, Z., LeBerichel, J., Chang, C., Jamal, H., Akturk, G., Chaddha, U., & 16 othersMathews, K., Acquah, S., Brown, S. A., Reiss, M., Harkin, T., Feldmann, M., Powell, C. A., Hook, J. L., Kim-Schulze, S., Rahman, A. H., Brown, B. D., Beckmann, N. D., Gnjatic, S., Kenigsberg, E., Charney, A. W. & Merad, M., 14 Sep 2022, In: Science Translational Medicine. 14, 662, abn5168.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

C10orf99/GPR15L Regulates Proinflammatory Response of Keratinocytes and Barrier Formation of the Skin

Dainichi, T., Nakano, Y., Doi, H., Nakamizo, S., Nakajima, S., Matsumoto, R., Farkas, T., Wong, P. M., Narang, V., Moreno Traspas, R., Kawakami, E., Guttman-Yassky, E., Dreesen, O., Litman, T., Reversade, B. & Kabashima, K., 22 Feb 2022, In: Frontiers in Immunology. 13, 825032.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Case Series: Convalescent Plasma Therapy for Patients with COVID-19 and Primary Antibody Deficiency

Lang-Meli, J., Fuchs, J., Mathé, P., Ho, H. E., Kern, L., Jaki, L., Rusignuolo, G., Mertins, S., Somogyi, V., Neumann-Haefelin, C., Trinkmann, F., Müller, M., Thimme, R., Umhau, M., Quinti, I., Wagner, D., Panning, M., Cunningham-Rundles, C., Laubner, K. & Warnatz, K., Feb 2022, In: Journal of Clinical Immunology. 42, 2, p. 253-265 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

9 Scopus citations

Characterization of acne associated with upadacitinib treatment in patients with moderate-to-severe atopic dermatitis: A post hoc integrated analysis of 3 phase 3 randomized, double-blind, placebo-controlled trials

Mendes-Bastos, P., Ladizinski, B., Guttman-Yassky, E., Jiang, P., Liu, J., Prajapati, V. H., Simpson, E. L., Vigna, N., Teixeira, H. D. & Barbarot, S., Oct 2022, In: Journal of the American Academy of Dermatology. 87, 4, p. 784-791 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Chronic Granulomatous Disease With Inflammatory Bowel Disease: Clinical Presentation, Treatment, and Outcomes From the USIDNET Registry

LaBere, B., Gutierrez, M. J., Wright, H., Garabedian, E., Ochs, H. D., Fuleihan, R. L., Secord, E., Marsh, R., Sullivan, K. E., Cunningham-Rundles, C., Notarangelo, L. D. & Chen, K., May 2022, In: Journal of Allergy and Clinical Immunology: In Practice. 10, 5, p. 1325-1333.e5

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4

Campisi, L., Chizari, S., Ho, J. S. Y., Gromova, A., Arnold, F., Mosca, L., Mei, X., Fstkchyan, Y., Torre, D., Beharry, C., Garcia-Forn, M., Jiménez-Alcázar, M., Korobeynikov, V. A., Prazich, J., Fayad, Z. A., Seldin, M. M., De Rubeis, S., Bennett, C. L., Ostrow, L. W., Lunetta, C., & 6 othersSquatrito, M., Byun, M., Shneider, N. A., Jiang, N., La Spada, A. R. & Marazzi, I., 30 Jun 2022, In: Nature. 606, 7916, p. 945-952 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Convergence of cytokine dysregulation and antibody deficiency in common variable immunodeficiency with inflammatory complications

Abyazi, M. L., Bell, K. A., Gyimesi, G., Baker, T. S., Byun, M., Ko, H. M., Cunningham-Rundles, C., Feng, F. & Maglione, P. J., Jan 2022, In: Journal of Allergy and Clinical Immunology. 149, 1, p. 315-326.e9

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

COVID-19 Symptoms Are Attenuated in Moderate-to-Severe Atopic Dermatitis Patients Treated with Dupilumab

Ungar, B., Glickman, J. W., Golant, A. K., Dubin, C., Marushchak, O., Gontzes, A., Mikhaylov, D., Singer, G. K., Baum, D., Wei, N., Sanin, A., Gruenstein, D., Lebwohl, M. G., Pavel, A. B. & Guttman-Yassky, E., Jan 2022, In: Journal of Allergy and Clinical Immunology: In Practice. 10, 1, p. 134-142 9 p.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Development of an HIV reporter virus that identifies latently infected CD4⁺ T cells

Kim, E. H., Manganaro, L., Schotsaert, M., Brown, B. D., Mulder, L. C. F. & Simon, V., 20 Jun 2022, In: Cell Reports Methods. 2, 6, 100238.

Research output: Contribution to journal › Article › peer-review

Open Access

Disease characteristics, comorbidities, treatment patterns and quality of life impact in children <12 years old with atopic dermatitis: Interim results from the PEDISTAD Real-World Registry

Paller, A. S., Guttman-Yassky, E., Schuttelaar, M. L. A., Irvine, A. D., Baselga, E., Kataoka, Y., Antila, M., de Bruin-Weller, M. S., Marcoux, D., Abramova, A., Rizova, E., Liu, C. & Zhang, A., Nov 2022, In: Journal of the American Academy of Dermatology. 87, 5, p. 1104-1108 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Distinct skin microbiome community structures in congenital ichthyosis

Tham, K. C., Lefferdink, R., Duan, K., Lim, S. S., Wong, X. F. C. C., Ibler, E., Wu, B., Abu-Zayed, H., Rangel, S. M., Del Duca, E., Chowdhury, M., Chima, M., Kim, H. J., Lee, B., Guttman-Yassky, E., Paller, A. S. & Common, J. E. A., Oct 2022, In: British Journal of Dermatology. 187, 4, p. 557-570 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Dupilumab Improves Clinical Scores in Children and Adolescents With Moderate to Severe Atopic Dermatitis: A Real-World, Single-Center Study

Pagan, A. D., David, E., Ungar, B., Ghalili, S., He, H. & Guttman-Yassky, E., Sep 2022, In: Journal of Allergy and Clinical Immunology: In Practice. 10, 9, p. 2378-2385 8 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

EAACI Biologicals Guidelines—Omalizumab for the treatment of chronic spontaneous urticaria in adults and in the paediatric population 12–17 years old

Agache, I., Akdis, C. A., Akdis, M., Brockow, K., Chivato, T., del Giacco, S., Eiwegger, T., Eyerich, K., Giménez-Arnau, A., Gutermuth, J., Guttman-Yassky, E., Maurer, M., Ogg, G., Ong, P. Y., O’Mahony, L., Schwarze, J., Warner, A., Werfel, T., Palomares, O. & Jutel, M., Jan 2022, In: Allergy: European Journal of Allergy and Clinical Immunology. 77, 1, p. 17-38 22 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Efficacy and Safety of Upadacitinib in Patients With Moderate to Severe Atopic Dermatitis: Analysis of Follow-up Data From the Measure Up 1 and Measure Up 2 Randomized Clinical Trials

Simpson, E. L., Papp, K. A., Blauvelt, A., Chu, C. Y., Hong, H. C. H., Katoh, N., Calimlim, B. M., Thyssen, J. P., Chiou, A. S., Bissonnette, R., Stein Gold, L. F., Wegzyn, C., Hu, X., Liu, M., Liu, J., Tenorio, A. R., Chu, A. D. & Guttman-Yassky, E., Apr 2022, In: JAMA Dermatology. 158, 4, p. 404-413 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

Elevated T-cell Exhaustion and Urinary Tumor DNA Levels Are Associated with Bacillus Calmette-Guérin Failure in Patients with Non–muscle-invasive Bladder Cancer

Strandgaard, T., Lindskrog, S. V., Nordentoft, I., Christensen, E., Birkenkamp-Demtröder, K., Andreasen, T. G., Lamy, P., Kjær, A., Ranti, D., Wang, Y. A., Bieber, C., Prip, F., Rasmussen, J., Steiniche, T., Birkbak, N., Sfakianos, J., Horowitz, A., Jensen, J. B. & Dyrskjøt, L., Dec 2022, In: European Urology. 82, 6, p. 646-656 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Excessive negative regulation of type I interferon disrupts viral control in individuals with Down syndrome

Malle, L., Martin-Fernandez, M., Buta, S., Richardson, A., Bush, D. & Bogunovic, D., 8 Nov 2022, In: Immunity. 55, 11, p. 2074-2084.e5

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Expanding cross-presenting dendritic cells enhances oncolytic virotherapy and is critical for long-term anti-tumor immunity

Svensson-Arvelund, J., Cuadrado-Castano, S., Pantsulaia, G., Kim, K., Aleynick, M., Hammerich, L., Upadhyay, R., Yellin, M., Marsh, H., Oreper, D., Jhunjhunwala, S., Moussion, C., Merad, M., Brown, B. D., García-Sastre, A. & Brody, J. D., Dec 2022, In: Nature Communications. 13, 1, 7149.

Research output: Contribution to journal › Article › peer-review

Open Access

Genomic characterization of lymphomas in patients with inborn errors of immunity

Ye, X., Maglione, P. J., Wehr, C., Li, X., Wang, Y., Abolhassani, H., Deripapa, E., Liu, D., Borte, S., Du, L., Wan, H., Plötner, A., Giannoula, Y., Ko, H. B., Hou, Y., Zhu, S., Grossman, J. K., Sander, B., Grimbacher, B., Hammarström, L., & 7 othersFedorova, A., Rosenzweig, S. D., Shcherbina, A., Wu, K., Warnatz, K., Cunningham-Rundles, C. & Pan-Hammarström, Q., 27 Sep 2022, In: Blood advances. 6, 18, p. 5403-5414 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Human Inborn Errors of Immunity: 2022 Update on the Classification from the International Union of Immunological Societies Expert Committee

Tangye, S. G., Al-Herz, W., Bousfiha, A., Cunningham-Rundles, C., Franco, J. L., Holland, S. M., Klein, C., Morio, T., Oksenhendler, E., Picard, C., Puel, A., Puck, J., Seppänen, M. R. J., Somech, R., Su, H. C., Sullivan, K. E., Torgerson, T. R. & Meyts, I., Oct 2022, In: Journal of Clinical Immunology. 42, 7, p. 1473-1507 35 p.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

Human OTULIN haploinsufficiency impairs cell-intrinsic immunity to staphylococcal a-toxin

Spaan, A. N., Neehus, A. L., Laplantine, E., Staels, F., Ogishi, M., Seeleuthner, Y., Rapaport, F., Lacey, K. A., Van Nieuwenhove, E., Chrabieh, M., Hum, D., Migaud, M., Izmiryan, A., Lorenzo, L., Kochetkov, T., Heesterbeek, D. A. C., Bardoel, B. W., DuMont, A. L., Dobbs, K., Chardonnet, S., & 42 othersHeissel, S., Baslan, T., Zhang, P., Yang, R., Bogunovic, D., Wunderink, H. F., Haas, P. J. A., Molina, H., Van Buggenhout, G., Lyonnet, S., Notarangelo, L. D., Seppänen, M. R. J., Weil, R., Seminario, G., Gomez-Tello, H., Wouters, C., Mesdaghi, M., Shahrooei, M., Bossuyt, X., Sag, E., Topaloglu, R., Ozen, S., Leavis, H. L., van Eijk, M. M. J., Bezrodnik, L., Galicia, L. B., Hovnanian, A., Nassif, A., Bader-Meunier, B., Neven, B., Meyts, I., Schrijvers, R., Puel, A., Bustamante, J., Aksentijevich, I., Kastner, D. L., Torres, V. J., Humblet-Baron, S., Liston, A., Abel, L., Boisson, B. & Casanova, J. L., 17 Jun 2022, In: Science. 376, 6599, eabm6380.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factor

Danziger, O., Patel, R. S., DeGrace, E. J., Rosen, M. R. & Rosenberg, B. R., Apr 2022, In: PLoS Pathogens. 18, 4, e1010464.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

In Vivo miRNA Decoy Screen Reveals miR-124a as a Suppressor of Melanoma Metastasis

Moubarak, R. S., Koetz-Ploch, L., Mullokandov, G., Gaziel, A., de Pablos-Aragoneses, A., Argibay, D., Kleffman, K., Sokolova, E., Berwick, M., Thomas, N. E., Osman, I., Brown, B. D. & Hernando, E., 4 Apr 2022, In: Frontiers in Oncology. 12, 852952.

Research output: Contribution to journal › Article › peer-review

Open Access

ISG15 deficiency restricts HIV-1 infection

Jurczyszak, D., Manganaro, L., Buta, S., Gruber, C., Martin-Fernandez, M., Taft, J., Patel, R., Cipolla, M., Alshammary, H., Mulder, L. C. F., Sachidanandam, R., Bogunovic, D. & Simon, V., Mar 2022, In: PLoS Pathogens. 18, 3, e1010405.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Limited extent and consequences of pancreatic SARS-CoV-2 infection

van der Heide, V., Jangra, S., Cohen, P., Rathnasinghe, R., Aslam, S., Aydillo, T., Geanon, D., Handler, D., Kelley, G., Lee, B., Rahman, A., Dawson, T., Qi, J., D'Souza, D., Kim-Schulze, S., Panzer, J. K., Caicedo, A., Kusmartseva, I., Posgai, A. L., Atkinson, M. A., & 5 othersAlbrecht, R. A., García-Sastre, A., Rosenberg, B. R., Schotsaert, M. & Homann, D., 15 Mar 2022, In: Cell Reports. 38, 11, 110508.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Long-Term Efficacy and Safety of Dupilumab in Adolescents with Moderate-to-Severe Atopic Dermatitis: Results Through Week 52 from a Phase III Open-Label Extension Trial (LIBERTY AD PED-OLE)

Blauvelt, A., Guttman-Yassky, E., Paller, A. S., Simpson, E. L., Cork, M. J., Weisman, J., Browning, J., Soong, W., Sun, X., Chen, Z., Kosloski, M. P., Kamal, M. A., Delevry, D., Chuang, C. C., O’Malley, J. T. & Bansal, A., May 2022, In: American Journal of Clinical Dermatology. 23, 3, p. 365-383 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Maintenance, withdrawal, and re-treatment with ritlecitinib and brepocitinib in patients with alopecia areata in a single-blind extension of a phase 2a randomized clinical trial

Peeva, E., Guttman-Yassky, E., Banerjee, A., Sinclair, R., Cox, L. A., Zhu, L., Zhu, H., Vincent, M. & King, B., Aug 2022, In: Journal of the American Academy of Dermatology. 87, 2, p. 390-393 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Mapping atopic dermatitis and anti–IL-22 response signatures to type 2–low severe neutrophilic asthma

U-BIOPRED Study Group, Jan 2022, In: Journal of Allergy and Clinical Immunology. 149, 1, p. 89-101 13 p.

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Center for Inborn Errors of Immunity

Research output

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