Center for Affective Neuroscience

Projects

Projects per year 1984 2004 2009 2010 2012 2015 2016 2017 2018 2019 2020 2026

• 72 Active
• 182 Finished

Projects per year

Search results

• Finished

  Circuit mechanisms of self-organized cognitive strategies

  Rich, E. E. L. & Rich, E.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  5/02/20 → 31/01/23

  Project: Research

  • Short-Term Memory 100%
  • Cognition 65%
  • Memory 58%
  • Prefrontal Cortex 44%
  • Corpus Striatum 40%

• Neural Mechanisms of Self-Generated Mnemonic Strategies.

  Rich, E.

  Whitehall Foundation

  1/01/20 → 31/12/22

  Project: Research

• Regulation of PTSD Via Neuropeptidergic Signaling in the Brain-Vagus-Body Axis.

  Rajbhandari, A.

  Whitehall Foundation

  1/01/20 → 31/12/20

  Project: Research

• Multi-region 'Network of Networks' Recurrent Neural Network Models of Adaptive and Maladaptive Learning

  Rajan, K.

  National Institute of Biomedical Imaging and Bioengineering

  16/09/19 → 15/09/22

  Project: Research

  • Recurrent neural networks 100%
  • Brain 48%
  • Networks (circuits) 26%
  • Communication 11%
  • Pipelines 9%

• Neuroimmune modulation of neuronal function during cocaine conditioning

  Shuman, T. & Kiraly, D.

  National Institute on Drug Abuse

  15/09/19 → 31/08/21

  Project: Research

  • Granulocyte Colony-Stimulating Factor 100%
  • Cocaine 93%
  • Microglia 67%
  • Nucleus Accumbens 43%
  • Granulocyte Colony-Stimulating Factor Receptors 41%

• Development of new photo-releasable neuropeptide nano-vesicles for studying modulation in the brain

  Qin, Z. & Slesinger, P.

  National Institute of Neurological Disorders and Stroke

  1/09/19 → 31/08/22

  Project: Research

  • Neuropeptides 100%
  • Brain 32%
  • Photons 20%
  • Neuropeptide Receptors 9%
  • Technology 8%

• Molecular Neurobiology of Human Drug Abuse

  Hurd, Y.

  National Institute on Drug Abuse

  1/09/19 → 31/08/20

  Project: Research

  • Heroin 100%
  • Opioid Analgesics 90%
  • Opioid-Related Disorders 71%
  • Neurobiology 68%
  • Substance-Related Disorders 51%

• NCS-FO: State Representations in Multi-purpose and Multi-region Neural Network Models of Cognition

  Rajan, K., Rich, E. & Rudebeck, P.

  National Science Foundation

  1/09/19 → 31/08/22

  Project: Research

  • Brain 100%
  • Neural networks 46%
  • Switches 39%
  • Recurrent neural networks 34%
  • Artificial intelligence 28%

• Interneuron and Network Synchrony in Alzheimer's Disease

  Shuman, T.

  National Institute of Neurological Disorders and Stroke

  15/08/19 → 31/07/21

  Project: Research

  • Interneurons 100%
  • Alzheimer Disease 74%
  • Memory 37%
  • Dentate Gyrus 15%
  • Cognitive Dysfunction 11%

• Determination of the GIRK channel proteome

  Slesinger, P.

  National Institute on Drug Abuse

  1/08/19 → 31/07/21

  Project: Research

  • Proteome 100%
  • Proteins 43%
  • Reward 25%
  • Inwardly Rectifying Potassium Channels 18%
  • Biotin 14%

• A Female Specific Role of RGSz1 in Modulation of Chronic Pain

  Zachariou, V.

  National Institute of Neurological Disorders and Stroke

  1/07/19 → 30/06/20

  Project: Research

  • Periaqueductal Gray 100%
  • Chronic Pain 79%
  • Hyperalgesia 51%
  • Signal Transduction 49%
  • G-Protein-Coupled Receptors 31%

• Characterizing the inflammatory phenotype of human and mouse models of depression

  Chan, K. & Russo, S.

  Institute of Neurosciences, Mental Health and Addiction

  1/06/19 → 31/05/22

  Project: Research

  • Major Depressive Disorder 100%
  • Inflammation 56%
  • Depression 54%
  • Phenotype 33%
  • Brain 26%

• PTSD Prevention Using Oral Hydrocortisone in the Immediate Aftermath of Trauma

  Yehuda, R.

  U.S. Army

  1/05/19 → 1/05/19

  Project: Research

  • Hydrocortisone 100%
  • Post-Traumatic Stress Disorders 85%
  • Wounds and Injuries 50%
  • Survivors 23%
  • Mental Health 21%

• Studying Atherosclerosis Macrophage Dynamics by Combined PET and Fluorine-MRI

  Fayad, Z. & Fayad, Z. A.

  National Heart, Lung, and Blood Institute

  15/01/19 → 31/12/22

  Project: Research

  • Fluorine 100%
  • Atherosclerosis 61%
  • Macrophages 50%
  • Magnetic Resonance Imaging 47%
  • Positron-Emission Tomography 42%

• Neural Mechanisms of Self- Generated Mnemonic Strategies

  Rich, E.

  Whitehall Foundation

  1/01/19 → 31/12/21

  Project: Research

• Development of novel therapeutics for opioid dependence

  Kenny, P. & Kamenecka, T. M.

  National Institute on Drug Abuse

  30/09/18 → 31/08/20

  Project: Research

  • Opioid-Related Disorders 100%
  • Opioid Analgesics 95%
  • Habenula 64%
  • Oxycodone 62%
  • Structure-Activity Relationship 36%

• Mechanistic and causal basis of fMRI functional connectivity in non-human primates

  Rudebeck, P. & Russ, B. E.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  18/09/18 → 17/09/22

  Project: Research

  • Magnetic Resonance Imaging 100%
  • Primates 78%
  • Oxygen 38%
  • Prefrontal Cortex 32%
  • Brain 26%

• Neuro-Immune Biotypes of Depression: Towards Pathophysiology-Based Diagnosis and Personalized Treatment

  Murrough, J.

  Dana Foundation

  6/09/18 → 5/09/21

  Project: Research

  • Major Depressive Disorder 100%
  • Blood-Brain Barrier 57%
  • Depression 41%
  • Tegmentum Mesencephali 30%
  • Anhedonia 29%

• Mechanism of activation and modulation in human GABA(B) receptor

  Fan, Q. R., Quick, M. & Slesinger, P.

  National Institute of General Medical Sciences

  1/09/18 → 31/07/22

  Project: Research

  • GABA-B Receptors 100%
  • GTP-Binding Proteins 75%
  • gamma-Aminobutyric Acid 56%
  • Structural Models 54%
  • Potassium Channels 33%

• TRAF6 Nanoimmunotherapy to resolve plaque inflammation

  Fayad, Z. & Mulder, W.

  National Heart, Lung, and Blood Institute

  15/08/18 → 30/06/20

  Project: Research

  • TNF Receptor-Associated Factor 6 100%
  • HDL Lipoproteins 82%
  • Primates 41%
  • Inflammation 39%
  • Apolipoproteins E 35%

• Parallel Multimodal High-throughput screening to identify activators of the orexin receptors

  Kamenecka, T. M., Kenny, P., Scampavia, L. D., Kamenecka, T. T. M., Scampavia, L. L. D. & Kenny, P. P. J.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  5/07/18 → 30/09/22

  Project: Research

  • Orexin Receptors 100%
  • Orexins 84%
  • Orexin Receptor Antagonists 26%
  • suvorexant 14%
  • Pharmaceutical Chemistry 11%

• Prefrontal circuit mechanisms of threat conditioning

  Clem, R. R. L. & Clem, R.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  1/04/18 → 31/12/22

  Project: Research

  • Interneurons 100%
  • Memory 80%
  • Somatostatin 65%
  • Fear 61%
  • Parvalbumins 60%

• Cellular substrates of early life trauma

  Clem, R.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  1/04/18 → 30/06/20

  Project: Research

  • Prefrontal Cortex 100%
  • Neurons 84%
  • Wounds and Injuries 49%
  • Anxiety 39%
  • Optogenetics 35%

• Neural mechanisms of self-generated mnemonic strategies

  Rich, E.

  Whitehall Foundation

  1/01/18 → 31/12/20

  Project: Research

• Role of lateral habenula orexin receptor signaling in aggressive social behavior

  Russo, S.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  15/09/17 → 30/06/22

  Project: Research

  • Habenula 100%
  • Orexin Receptors 98%
  • Social Behavior 87%
  • Interpersonal Relations 33%
  • Orexins 27%

• Targeting HDAC6 for the treatment of neuropathic pain

  Zachariou, V.

  National Institute of Neurological Disorders and Stroke

  15/08/17 → 31/07/19

  Project: Research

  • Neuralgia 100%
  • Protein Isoforms 73%
  • Raphe Nuclei 60%
  • Analgesics 58%
  • Histone Deacetylase Inhibitors 52%

• MicroRNAs in schizophrenia

  Kenny, P.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  21/07/17 → 30/04/22

  Project: Research

  • Parvalbumins 100%
  • Interneurons 77%
  • MicroRNAs 64%
  • Schizophrenia 54%
  • Mouse Mirn206 microRNA 23%

• NEUROIMAGING OF RESILIENCE IN WORLD TRADE CENTER RESPONDERS: A FOCUS ON EMOTIONAL PROCESSING, REWARD AND SOCIAL COGNITION

  Feder, A. & Pietrzak, R. H. R. H.

  National Institute for Occupational Safety and Health

  1/07/17 → 30/06/21

  Project: Research

  • Psychological Resilience 100%
  • Reward 53%
  • Post-Traumatic Stress Disorders 46%
  • Cognition 37%
  • Emotional Regulation 36%

• NEUROIMAGING OF RESILIENCE IN WORLD TRADE CENTER RESPONDERS: A FOCUS ON EMOTIONAL PROCESSING, REWARD AND SOCIAL COGNITION

  Feder, A., Perez-Rodriguez, M. D. L. M. & Pietrzak, R. H. R. H.

  National Institute for Occupational Safety and Health

  1/07/17 → 30/06/21

  Project: Research

  • Psychological Resilience 100%
  • Reward 53%
  • Post-Traumatic Stress Disorders 46%
  • Cognition 37%
  • Emotional Regulation 36%

• NEUROIMAGING OF RESILIENCE IN WORLD TRADE CENTER RESPONDERS: A FOCUS ON EMOTIONAL PROCESSING, REWARD AND SOCIAL COGNITION

  Feder, A. & Pietrzak, R. H. R. H.

  National Institute for Occupational Safety and Health

  1/07/17 → 30/06/21

  Project: Research

  • Psychological Resilience 100%
  • Reward 53%
  • Post-Traumatic Stress Disorders 46%
  • Cognition 37%
  • Emotional Regulation 36%

• Ga68-DOTATATE PET imaging of plaque inflammation

  Fayad, Z.

  National Heart, Lung, and Blood Institute

  15/05/17 → 30/04/21

  Project: Research

  • dotatate gallium ga-68 100%
  • Macrophages 40%
  • Inflammation 29%
  • Cardiovascular Diseases 29%
  • Fluorodeoxyglucose F18 25%

• NEUROBIOLOGY OF AFFECTIVE INSTABILITY IN VETERANS AT LOW AND HIGH RISK FOR SUICIDE

  Hazlett, E.

  U.S. Department of Veterans Affairs

  1/04/17 → 31/03/21

  Project: Research

  • Suicide 100%
  • Veterans 99%
  • Neurobiology 74%
  • Emotional Regulation 29%
  • Emotions 20%

• Neurobiology of Affective Instability in Veterans at Low and High Risk for Suicide

  Hazlett, E.

  U.S. Department of Veterans Affairs

  1/04/17 → 31/03/22

  Project: Research

  • Veterans 100%
  • Suicide 92%
  • Neurobiology 82%
  • Emotional Regulation 38%
  • Emotions 17%

• Administrative Core

  Nestler, E.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  1/04/17 → 28/02/22

  Project: Research

  • trainee 100%
  • communication 86%
  • advocacy organizations 73%
  • ethical conduct 72%
  • conduct of research 70%

• Developmental Chromatin Scars in Mouse Depression Models

  Nestler, E.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  1/04/17 → 28/02/22

  Project: Research

  • Ventral Tegmental Area 100%
  • Chromatin 91%
  • Nucleus Accumbens 89%
  • Cicatrix 67%
  • Depression 54%

• Animal Models Core

  Zachariou, V.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  1/04/17 → 28/02/22

  Project: Research

  • Animal Models 100%
  • Depression 94%
  • Epigenomics 63%
  • Genes 58%
  • Photometry 52%

• NEUROBIOLOGY OF AFFECTIVE INSTABILITY IN VETERANS AT LOW AND HIGH RISK FOR SUICIDE

  Hazlett, E.

  U.S. Department of Veterans Affairs

  1/04/17 → 31/03/21

  Project: Research

• NEUROBIOLOGY OF AFFECTIVE INSTABILITY IN VETERANS AT LOW AND HIGH RISK FOR SUICIDE

  Hazlett, E.

  U.S. Department of Veterans Affairs

  1/04/17 → 31/03/21

  Project: Research

  • Suicide 100%
  • Veterans 99%
  • Neurobiology 74%
  • Emotional Regulation 29%
  • Emotions 20%

• NEUROBIOLOGY OF AFFECTIVE INSTABILITY IN VETERANS AT LOW AND HIGH RISK FOR SUICIDE

  Hazlett, E.

  U.S. Department of Veterans Affairs

  1/04/17 → 31/03/21

  Project: Research

  • Suicide 100%
  • Veterans 99%
  • Neurobiology 74%
  • Emotional Regulation 29%
  • Emotions 20%

• Neural mechanisms of social affect induction

  Rudebeck, P. & Bliss-Moreau, E.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  24/03/17 → 28/02/19

  Project: Research

  • Gyrus Cinguli 100%
  • Amygdala 96%
  • Primates 38%
  • Mood Disorders 26%
  • Neurons 17%

• Stress and Atherosclerotic Plaque Macrophages - A Systems Biology Approach

  Fayad, Z., Mani, V., Mulder, W. & Swirski, F.

  National Heart, Lung, and Blood Institute

  17/03/17 → 28/02/22

  Project: Research

  • Systems Biology 100%
  • Atherosclerotic Plaques 87%
  • Atherosclerosis 76%
  • Macrophages 68%
  • Cardiovascular Diseases 45%

• Realization of Optical Cell-based Reporters for in vivo Detection of Neuropeptides

  Slesinger, P. & Kleinfeld, D.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  9/09/16 → 30/06/20

  Project: Research

  • Neuropeptides 100%
  • Brain 25%
  • Neurotransmitter Agents 22%
  • Learning 19%
  • G-Protein-Coupled Receptors 17%

• INTERNET-BASED PSYCHOTHERAPIES FOR PTSD SYMPTOMS IN WTC RESPONDERS

  Feder, A. & Pietrzak, R. H. R. H.

  National Institute for Occupational Safety and Health

  1/09/16 → 31/08/19

  Project: Research

  • Post-Traumatic Stress Disorders 100%
  • Internet 98%
  • Psychotherapy 66%
  • Occupational Groups 32%
  • Therapeutic Alliance 30%

• PET/MRI of the brain-hematopoiesis-atherosclerosis axis in PTSD patients

  Fayad, Z.

  National Heart, Lung, and Blood Institute

  1/09/16 → 28/02/22

  Project: Research

  • Post-Traumatic Stress Disorders 100%
  • Hematopoiesis 97%
  • Atherosclerosis 78%
  • Magnetic Resonance Imaging 62%
  • Inflammation 48%

• Stress and atherosclerotic plaque macrophages - a systems biology approach

  Fayad, Z.

  National Heart, Lung, and Blood Institute

  1/09/16 → 28/02/22

  Project: Research

  • Biostatistics 100%
  • Macrophages 85%
  • Systems Biology 66%
  • Information management 35%

• INTERNET-BASED PSYCHOTHERAPIES FOR PTSD SYMPTOMS IN WTC RESPONDERS

  Feder, A. & Pietrzak, R. H. R. H.

  National Institute for Occupational Safety and Health

  1/09/16 → 31/08/19

  Project: Research

  • Post-Traumatic Stress Disorders 100%
  • Internet 98%
  • Psychotherapy 66%
  • Occupational Groups 32%
  • Therapeutic Alliance 30%

• A RANDOMIZED CONTROLLED TRIAL OF INTERNET CBT FOR PTSD IN WTC RESPONDERS

  Feder, A. & Pietrzak, R. H. R. H.

  National Institute for Occupational Safety and Health

  1/09/16 → 31/08/19

  Project: Research

  • Post-Traumatic Stress Disorders 100%
  • Internet 98%
  • Randomized Controlled Trials 41%
  • Occupational Groups 32%
  • Therapeutic Alliance 30%

• The relationship between glucocorticoid receptor activation and the neuronal hyperexcitability in the basolateral amygdala in the restraint stress-induced long-lasting anxiety and their implications in the impaired contextual fear extinction

  Munhoz, C. D. C. D. & Goosens, K.

  Fundação de Amparo à Pesquisa do Estado de São Paulo

  1/08/16 → 31/10/18

  Project: Research

  • Basolateral Nuclear Complex 100%
  • Psychological Extinction 81%
  • Fear 67%
  • Glucocorticoid Receptors 62%
  • Anxiety 60%

• Nicotinic receptors and alcohol reinforcement

  Kenny, P.

  National Institute on Alcohol Abuse and Alcoholism

  15/07/16 → 31/03/21

  Project: Research

  • Nicotinyl Alcohol 100%
  • Interpeduncular Nucleus 95%
  • Habenula 84%
  • Nicotinic Receptors 63%
  • Psychology Reinforcement 55%

• A new approach to the role of prefrontal-limbic circuits in anxiety disorders

  Rudebeck, P.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  1/07/16 → 31/03/21

  Project: Research

  • Anxiety Disorders 100%
  • Prefrontal Cortex 95%
  • Amygdala 74%
  • Haplorhini 69%
  • Neural Pathways 38%