Center for Affective Neuroscience

Projects

Projects per year 1984 2004 2009 2010 2012 2015 2016 2017 2018 2019 2020 2026

• 72 Active
• 182 Finished

Projects per year

Search results

• Active

  Epigenetic Mechanisms of Chronic Stress Action

  Nestler, E.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  13/12/22 → 30/11/23

  Project: Research

  • Psychological Stress 100%
  • Nucleus Accumbens 72%
  • Epigenomics 53%
  • Neurons 34%
  • Chromatin 29%

• Mesoscale dynamics underlying expectation bias in the orbitofrontal cortex

  Rich, E.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  1/12/22 → 30/11/23

  Project: Research

  • Motivation 100%
  • Prefrontal Cortex 97%
  • Electrocorticography 49%
  • Thinking 23%
  • Psychological Adaptation 13%

• Neural Network Models Constrained by Multiscale Data to Infer Minimal Functional Motifs in the Brain

  Rajan, K.

  National Institute on Drug Abuse

  15/09/22 → 14/09/25

  Project: Research

  • Brain 100%
  • Recurrent neural networks 61%
  • Neural networks 59%
  • Neurology 14%
  • Neurons 10%

• D-ISN: Evolution of Global Illicit Kidney Trade Networks: Identification, Reconstruction, and Disruption

  Rajan, K., Fu, M. M. C., Gentili, M. M. & El-amine, H. H.

  National Science Foundation

  1/07/22 → 30/06/26

  Project: Research

  • reconstruction 100%
  • estimation procedure 25%
  • simulation model 23%
  • intervention strategy 20%
  • Open Sources 19%

• Entorhinal-hippocampal interactions during progressive memory impairments in mouse models of Alzheimer's disease pathology

  Shuman, T.

  National Institute on Aging

  1/06/22 → 31/05/25

  Project: Research

  • Entorhinal Cortex 100%
  • Memory 64%
  • Pathology 61%
  • Alzheimer Disease 50%
  • Memory Disorders 34%

• Pharmacological Modulation of Nicotinic Signaling to Ameliorate Cognitive Deficits in a Fragile X Mouse Model

  Morishita, H. & Garkun, Y. Y.

  FRAXA Research Foundation

  1/01/22 → …

  Project: Research

  • Drug Receptors 100%
  • Nicotinic Receptors 80%
  • Pharmacology 72%
  • Nicotine 72%
  • Brain 71%

• Collaborative Research: NCS-FR: Understanding the neuropeptide modulation of brain circuits by advanced nanomaterials and imaging

  Slesinger, P.

  National Science Foundation

  1/09/21 → 31/08/25

  Project: Research

  • Neuropeptides 100%
  • Nanostructures 88%
  • Brain 69%
  • Neurotransmitter Agents 64%
  • Oxytocin 30%

• CAREER: Untangling Inter-Area Communication in the Brain Using Multi-Region Neural Networks

  Rajan, K.

  National Science Foundation

  1/09/21 → 31/08/26

  Project: Research

  • Brain 100%
  • Communication 45%
  • Neural networks 39%
  • Recurrent neural networks 18%
  • Animals 17%

• Molecular Neurobiology of Human Opioid Use Disorder

  Hurd, Y. Y. L. & Hurd, Y.

  National Institute on Drug Abuse

  15/07/21 → 31/03/23

  Project: Research

  • Heroin 100%
  • Opioid Analgesics 77%
  • Neurobiology 72%
  • Opioid-Related Disorders 55%
  • Self Administration 44%

• Neural Circuit Mechanisms of Stress-Impaired Social Reward

  Russo, S. & Russo, S. J.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  1/06/21 → 31/03/23

  Project: Research

  • Reward 100%
  • Interpersonal Relations 57%
  • Brain 17%
  • Neurotensin 14%
  • Optogenetics 14%

• Comparative Neuroanatomy at single-neuron resolution

  Rudebeck, P. & Clem, R.

  National Institute of Neurological Disorders and Stroke

  15/04/21 → 31/03/23

  Project: Research

  • neurons 100%
  • amygdala 90%
  • Primates 88%
  • Macaca 47%
  • frontal lobe 39%

• Cellular substrates of early life trauma

  Clem, R. & Clem, R. L.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  21/09/20 → 30/06/23

  Project: Research

  • Prefrontal Cortex 100%
  • Wounds and Injuries 47%
  • Anxiety 26%
  • Optogenetics 23%
  • Avoidance Learning 22%

• Development of novel therapeutics for opioid dependence

  Kenny, P., Kamenecka, T. M., Kenny, P. J. & Kamenecka, T. T. M.

  National Institute on Drug Abuse

  1/09/20 → 31/08/23

  Project: Research

  • Opioid-Related Disorders 100%
  • Opioid Analgesics 87%
  • Habenula 63%
  • Oxycodone 50%
  • Structure-Activity Relationship 35%

• A Female Specific Role of RGSz1 in Modulation of Chronic Pain

  Zachariou, V. & Zachariou, V.

  National Institute of Neurological Disorders and Stroke

  1/07/20 → 30/06/23

  Project: Research

  • Periaqueductal Gray 100%
  • Chronic Pain 86%
  • Hyperalgesia 42%
  • Signal Transduction 37%
  • Pain 36%

• Influence of Dietary Botanical Supplements on Biological and Behavioral Resilience

  Pasinetti, G., Simon, J. J. E., Murrough, J., Murrough, J. W., Pasinetti, G. M. & Simon, J. E.

  National Center for Complementary and Integrative Health

  1/07/20 → 30/06/23

  Project: Research

  • Dietary Supplements 100%
  • Interleukin-6 79%
  • Depression 18%
  • Polyphenols 15%
  • Interneurons 14%

• Clinical Pharmacology and Target Validation of BDPP for Stress-Related Disorders

  Murrough, J. W. & Murrough, J.

  National Center for Complementary and Integrative Health

  1/07/20 → 30/06/23

  Project: Research

  • Clinical Pharmacology 100%
  • Interleukin-6 82%
  • Psychological Stress 30%
  • Depression 30%
  • Treatment-Resistant Depressive Disorder 20%

• CTBI: TRAUMATIC BRAIN INJURY-INDUCED INFLAMMATION EFFECTS ON COGNITIVE EVALUATIONS AND RESPONSE INHIBITION: MECHANISMS OF INCREASED RISK FORSUICIDALITY

  Goodman, M. & Hazlett, E.

  U.S. Department of Veterans Affairs

  1/04/20 → 31/03/24

  Project: Research

• Circuits driving spatial coding deficits in epilepsy

  Shuman, T. & Shuman, T.

  National Institute of Neurological Disorders and Stroke

  1/02/20 → 31/12/23

  Project: Research

  • Epilepsy 100%
  • Hippocampus 71%
  • Entorhinal Cortex 68%
  • Temporal Lobe Epilepsy 30%
  • Place Cells 12%

• Closed-Loop Resynchronization of Epileptic Circuits

  Shuman, T.

  Citizens United for Research in Epilepsy

  1/01/20 → …

  Project: Research

  • Epilepsy 100%
  • Seizures 61%
  • Brain 38%
  • Psychological Inhibition 32%
  • Memory 28%

• YOUNG INVESTIGATOR 2020

  Rajbhandari, A.

  Brain and Behavior Research Foundation

  1/01/20 → …

  Project: Research

  • Research Personnel 100%
  • Anxiety Disorders 69%
  • Mood Disorders 69%
  • Brain Diseases 68%
  • Schizophrenia 58%

• Circuit mechanisms of retrospective memory-linking

  Cai, D. D. J. & Cai, D.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  3/12/19 → 31/10/23

  Project: Research

  • Traumatic Stress Disorders 100%
  • Memory 81%
  • Fear 55%
  • Post-Traumatic Stress Disorders 23%
  • Wounds and Injuries 12%

• Neural mechanisms of affective processing in prefrontal-limbic circuits

  Rudebeck, P. & Rudebeck, P.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  11/09/19 → 30/06/23

  Project: Research

  • Reward 100%
  • Gyrus Cinguli 73%
  • Anhedonia 37%
  • Motivation 29%
  • Ventral Striatum 20%

• How does the brain maximize storage capacity?

  Cai, D.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  1/09/19 → 31/05/24

  Project: Research

  • Memory 100%
  • Efficiency 89%
  • Brain 71%
  • Hippocampus 65%
  • Psychological Generalization 36%

• Cell-type-specific NRXN1alpha alternative splicing changes in psychiatric disease

  Fang, G. G., Brennand, K., Fang, G., Brennand, K. K. J., Slesinger, P. P. A. & Slesinger, P.

  NATIONAL INSTITUTE OF MENTAL HEALTH

  18/07/19 → 30/04/23

  Project: Research

  • Alternative Splicing 100%
  • Mental Disorders 74%
  • Neurons 48%
  • Mutation 44%
  • Schizophrenia 35%

• PTSD PREVENTION USING ORAL HYDROCORTISONE IN THE IMMEDIATE AFTERMATH OF TRAUMA

  Yehuda, R.

  Congressionally Directed Medical Research Programs

  1/05/19 → 30/04/23

  Project: Research

  • Hydrocortisone 100%
  • Post-Traumatic Stress Disorders 87%
  • Wounds and Injuries 43%
  • Placebos 30%
  • Hospital Emergency Service 17%

• Transcriptional Mechanisms of Drug Addiction

  Nestler, E., Schaefer, A. A., Hurd, Y. L., Kenny, P. J., Shen, L. L., Nestler, E. J., Kenny, P., Schaefer, A., Shen, L., Zachariou, V. V., Hurd, Y. & Zachariou, V.

  National Institute on Drug Abuse

  15/02/19 → 30/11/23

  Project: Research

  • Substance-Related Disorders 100%
  • Brain 48%
  • Animal Models 30%
  • Chromatin 29%
  • Reward 27%

• Animal Models Core

  Zachariou, V. & Zachariou, V. V.

  National Institute on Drug Abuse

  1/02/19 → 30/11/23

  Project: Research

  • Animal Models 100%
  • Photometry 45%
  • Research Personnel 42%
  • Optogenetics 40%
  • Microdissection 39%

• Administrative Core

  Nestler, E. J. & Nestler, E.

  National Institute on Drug Abuse

  1/02/19 → 30/11/23

  Project: Research

  • advocacy organizations 100%
  • ethical conduct 98%
  • communication 78%
  • Career development 76%
  • scientific community 75%

• Regulation of Gene Enhancers in Human Heroin Use

  Hurd, Y. L. & Hurd, Y.

  National Institute on Drug Abuse

  1/02/19 → 30/11/23

  Project: Research

  • Heroin 100%
  • Chromatin Immunoprecipitation Sequencing 36%
  • Heroin Dependence 32%
  • Genes 31%
  • Histones 26%

• Novel Transcription Factors in Stimulant and Opiate Action

  Nestler, E. J. & Nestler, E.

  National Institute on Drug Abuse

  1/02/19 → 30/11/23

  Project: Research

  • Cocaine 100%
  • Opiate Alkaloids 96%
  • Nucleus Accumbens 81%
  • Transcription Factors 78%
  • Substance-Related Disorders 65%

• Role for Circular RNAs in Compulsive Cocaine Intake

  Kenny, P. J. & Kenny, P.

  National Institute on Drug Abuse

  1/02/19 → 30/11/23

  Project: Research

  • Circular RNAs 100%
  • Cocaine 75%
  • Nucleus Accumbens 24%
  • Substance-Related Disorders 7%
  • Neurons 6%

• Role of autism risk genes in prefrontal circuits underlying social processing in mice

  Morishita, H.

  Simons Foundation Autism Research Initiative

  1/01/19 → …

  Project: Research

  • Autism Spectrum Disorder 100%
  • Social Behavior 56%
  • Autistic Disorder 52%
  • Prefrontal Cortex 34%
  • Genes 33%

• Habenular immune signaling and addiction

  Kenny, P. & Kenny, P. J.

  National Institute on Drug Abuse

  30/09/18 → 30/06/23

  Project: Research

  • Habenula 100%
  • Nicotine 90%
  • Interleukin-18 65%
  • Microglia 50%
  • Interpeduncular Nucleus 48%

• Mechanisms of nicotine reinforcement

  Kenny, P. & Kenny, P. J.

  National Institute on Drug Abuse

  1/07/18 → 31/05/23

  Project: Research

  • T Cell Transcription Factor 1 100%
  • Nicotine 65%
  • Habenula 43%
  • Opioid-Related Disorders 12%
  • Interpeduncular Nucleus 12%

• PET nanoreporter image-guided breast cancer therapy

  Fayad, Z., Pérez-medina, C. C., Fayad, Z. A., Grimm, J. J., Mulder, W., Perez-Medina, C. & Reiner, T.

  National Cancer Institute

  15/06/18 → 31/05/23

  Project: Research

  • Nanomedicine 100%
  • Positron-Emission Tomography 68%
  • Breast Neoplasms 46%
  • liposomal doxorubicin 39%
  • Technology 33%

• CSR&D RESEARCH CAREER SCIENTIST AWARD APPLICATION

  Hazlett, E.

  U.S. Department of Veterans Affairs

  1/04/18 → 31/03/23

  Project: Research

• CSR&D RESEARCH CAREER SCIENTIST AWARD APPLICATION

  Hazlett, E.

  U.S. Department of Veterans Affairs

  1/04/18 → 31/03/23

  Project: Research

  • Schizophrenia 100%
  • White Matter 78%
  • Suicide 56%
  • Veterans 50%
  • Diffusion Tensor Imaging 41%

• CSR&D RESEARCH CAREER SCIENTIST AWARD APPLICATION

  Hazlett, E.

  U.S. Department of Veterans Affairs

  1/04/18 → 31/03/23

  Project: Research

  • Schizophrenia 100%
  • White Matter 78%
  • Suicide 56%
  • Veterans 50%
  • Diffusion Tensor Imaging 41%

• Mechanisms of epilepsy rescue with transplantation of interneuron precursor

  Shuman, T.

  American Epilepsy Society

  1/01/18 → …

  Project: Research

• Closed Loop Resynchronization of Epileptic Circuits

  Shuman, T.

  Citizens United for Research in Epilepsy

  1/01/18 → …

  Project: Research

  • Seizures 100%
  • Brain 47%
  • Memory 47%
  • Epilepsy 27%
  • Psychological Inhibition 26%

• Investigating the Role of Negative Valence in the Temporal Dynamics of Memory-Linking

  Cai, D.

  Brain Research Foundation

  1/01/18 → …

  Project: Research

  • Memory 100%
  • Fear 56%
  • Post-Traumatic Stress Disorders 31%
  • Memory Disorders 17%
  • Sleep 12%

• Pew Charitable Trust Award

  Rich, E.

  Pew Charitable Trusts

  1/01/18 → …

  Project: Research

  • Motivation 100%
  • Brain 34%
  • Reward 34%
  • Animals 17%
  • Substance-Related Disorders 15%

• YOUNG INVESTIGATOR 2018

  Rich, E.

  Brain and Behavior Research Foundation

  1/01/18 → …

  Project: Research

  • Research Personnel 100%
  • Anxiety Disorders 69%
  • Mood Disorders 69%
  • Brain Diseases 68%
  • Schizophrenia 58%

• PTSD Prevention Using Oral Hydrocortisone in the Immediate Aftermath of Trauma

  Yehuda, R.

  Congressionally Directed Medical Research Programs

  1/01/18 → …

  Project: Research

  • Hydrocortisone 100%
  • Post-Traumatic Stress Disorders 85%
  • Wounds and Injuries 50%
  • Survivors 23%
  • Mental Health 21%

• YOUNG INVESTIGATOR 2017

  Rajbhandari, A.

  Brain and Behavior Research Foundation

  1/01/17 → …

  Project: Research

  • Research Personnel 100%
  • Anxiety Disorders 69%
  • Mood Disorders 69%
  • Brain Diseases 68%
  • Schizophrenia 58%

• YOUNG INVESTIGATOR 2017

  Kiraly, D.

  Brain and Behavior Research Foundation

  1/01/17 → …

  Project: Research

  • Research Personnel 100%
  • Anxiety Disorders 69%
  • Mood Disorders 69%
  • Brain Diseases 68%
  • Schizophrenia 58%

• Leveraging ΔFosB as a potential therapeutic for Alzheimer's Disease

  Rudenko, G. G., Robison, A. A. J., Nestler, E., Zhou, J. J., Nestler, E. J., Robison, A. J., Rudenko, G. & Zhou, J.

  National Institute on Drug Abuse

  1/07/16 → 31/03/23

  Project: Research

  • Substance-Related Disorders 100%
  • Oxidation-Reduction 70%
  • Cognitive Dysfunction 60%
  • Organized Financing 43%
  • Pharmaceutical Preparations 37%

• Glial-mediated synaptic remodeling in drug addiction

  Dong, Y. Y., Dong, Y., Nestler, E. E. J. & Nestler, E.

  National Institute on Drug Abuse

  1/06/16 → 30/04/23

  Project: Research

  • Neuroglia 100%
  • Substance-Related Disorders 99%
  • Synapses 74%
  • Nucleus Accumbens 67%
  • Cocaine 65%

• DISTINGUISHED INVESTIGATOR 2016

  Yehuda, R.

  Brain and Behavior Research Foundation

  1/01/16 → …

  Project: Research

  • Research Personnel 100%
  • Behavioral Research 83%
  • Central Nervous System 44%
  • Population 23%

• DISTINGUISHED INVESTIGATOR 2015

  Kenny, P.

  Brain and Behavior Research Foundation

  1/01/15 → …

  Project: Research

  • Research Personnel 100%
  • Behavioral Research 83%
  • Central Nervous System 44%
  • Population 23%