Center for Advancement of Blood Cancer Therapies

Icahn School of Medicine at Mount Sinai

14409 Citations
62 h-index
381 Article
54 Review article
21 Comment/debate
17 Letter
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A MICA/B GAALIE-mutant antibody elicits potent natural killer cell-driven immunity in solid and hematologic malignancy models
Pimenta, R., Maurer, S., Zhong, X., Taciane da Silva Bortoleti, B., Quasem, S., Ribeiro de Lima Brandão, L., Marcellino, B., Dutta, A., Arriaga, J. M., Mascarenhas, J. & Ferrari de Andrade, L., 19 May 2026, In: Cell Reports Medicine. 7, 5, 102753.
Research output: Contribution to journal › Article › peer-review

Open Access
Armored macrophage-targeted CAR-T cells reset and reprogram the tumor microenvironment and control metastatic cancer growth
Mateus-Tique, J., Lakshmi, A., Singh, B., Iyer, R., Sánchez-Paulete, A. R., Falcomatà, C., Lin, M., Pantsulaia, G., Tepper, A., Nguyen, T., Amabile, A., Mollaoglu, G., Pia, L., Chhamalwan, D., Le Berichel, J., Potak, H., Colonna, M., Baccarini, A., Brody, J. & Merad, M. & 1 others, Brown, B. D., 9 Mar 2026, In: Cancer Cell. 44, 3, p. 534-550.e11
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
Artificial intelligence differentiates prefibrotic primary myelofibrosis with thrombocytosis from essential thrombocythemia using digitized bone marrow biopsy images
Srisuwananukorn, A., Loscocco, G. G., Dolezal, J. M., Kuykendall, A. T., Santi, R., Zhang, L., Singh, A. M., Guglielmelli, P., Vannucchi, A. M., Salama, M. E., Pearson, A. T. & Hoffman, R., May 2026, In: Leukemia. 40, 5, p. 1018-1026 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
A study of gene expression in the living human brain
Liharska, L. E., Park, Y. J., Ziafat, K., Wilkins, L., Silk, H., Linares, L. M., Thompson, R. C., Vornholt, E., Sullivan, B., Cohen, V., Kota, P., Feng, C., Cheng, E., Johnson, J. S., Rieder, M. K., Huang, J., Scarpa, J., Polanco, J., Moya, E. & Hashemi, A. & 8 others, Levin, M. A., Nadkarni, G. N., Sebra, R., Crary, J. F., Schadt, E. E., Beckmann, N. D., Kopell, B. H. & Charney, A. W., Jan 2026, In: Molecular Psychiatry. 31, 1, p. 137-157 21 p.
Research output: Contribution to journal › Article › peer-review

Open Access
5 Scopus citations
A synergistic interaction between PRMT5 and LSD1 inhibitors in AML
Param, N. J., Arceci, E., Fiorentino, F., Pignata, L., Torre, D., Gutiérrez-Trejo, N., Fong, J. Y., Goy, P. A., Han, B. Y., Lambona, C., Bello, E. D., Castiello, C., Barone, M., Schwarz, M., Arrowsmith, C., Ito, K., Scherle, P., Wee, D. K. B., Ndoye, S. & Tabaglio, T. & 9 others, Jeyasekharan, A. D., Lakshmanan, M., Cirilli, R., Habisch, H., Madl, T., Mattevi, A., Valente, S., Mai, A. & Guccione, E., 27 Mar 2026, In: Science advances. 12, 13, eaea4059.
Research output: Contribution to journal › Article › peer-review

Open Access
A Tumor-Promoting Inflammatory SPP1⁺ Macrophage–IL6–CRP Axis Drives Immune Dysfunction in Bladder Cancer
Tran, M. A., Cho, B. A., Izadmehr, S., Yoo, S. K., Youssef, D., Anker, J. F., Farkas, A. M., Figueiredo, I., Lee, K., Ananthanarayanan, A., Balan, S., Onkar, S., Banchereau, R., Gupta, S., Chhibber, A., Wang, L., Beaumont, K. G., Li, Z., Garcia-Barros, M. & Bicak, M. & 18 others, Cordon-Cardo, C., Brody, R., Kim-Schulze, S., Yuen, K., Mariathasan, S., Atiq, S. O., Adeyelu, T. T., Elliott, A., Barata, P., McKay, R. R., Gnjatic, S., Gonzalez-Kozlova, E., Mehrazin, R., Horowitz, A., Sfakianos, J. P., Chowell, D., Galsky, M. D. & Bhardwaj, N., Jun 2026, In: Cancer Discovery. 16, 6, p. 1126-1151 26 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Author Correction: The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis (Nature, (2021), 592, 7853, (296-301), 10.1038/s41586-021-03341-5)
Fidler, T. P., Xue, C., Yalcinkaya, M., Hardaway, B., Abramowicz, S., Xiao, T., Liu, W., Thomas, D. G., Hajebrahimi, M. A., Pircher, J., Silvestre-Roig, C., Kotini, A. G., Luchsinger, L. L., Wei, Y., Westerterp, M., Snoeck, H. W., Papapetrou, E. P., Schulz, C., Massberg, S. & Soehnlein, O. & 6 others, Ebert, B., Levine, R. L., Reilly, M. P., Libby, P., Wang, N. & Tall, A. R., 2026, (Accepted/In press) In: Nature.
Research output: Contribution to journal › Comment/debate

Open Access
Author Correction: A streamlined base editor engineering strategy to reduce bystander editing (Nature Communications, (2025), 16, 1, (8115), 10.1038/s41467-025-63609-6)
Valdez, I., O’Connor, I., Patel, D., Gierer, K., Harrington, J., Ellis, E., Caponetti, S. A., Sebra, R. P., Valley, H. C., Coote, K., Mense, M., Marro, S. G. & Jiang, T., Dec 2026, In: Nature Communications. 17, 1, 997.
Research output: Contribution to journal › Comment/debate

Open Access
Bacillus Calmette-Guérin (BCG) and Beyond: Is Systemic Immunotherapy for BCG-Naïve Non–Muscle-Invasive Bladder Cancer Progress or Overreach?
Kamat, A. M., Hensley, P. J., Maiorano, B. A., Li, R., Psutka, S. P., Mouw, K. W., Horowitz, A., Gupta, S. & Necchi, A., Mar 2026, In: Journal of Clinical Oncology. JCO-25-02670.
Research output: Contribution to journal › Article › peer-review

1 Scopus citations
Baseline absolute lymphocyte count, C-reactive protein, and ferritin predict CAR T cell-related toxicities and outcomes in multiple myeloma
Pan, D., Mouhieddine, T. H., Sheng, T., Fu, W., Moshier, E., Richter, J., Parekh, S., Jagannath, S., Chari, A., Rossi, A. C., Sanchez, L. J., Thibaud, S., Rodriguez, C., Cho, H. J. & Richard, S., May 2026, In: Bone Marrow Transplantation. 61, 5, p. 639-641 3 p.
Research output: Contribution to journal › Letter › peer-review
Complement-regulated homeostatic proliferation controls memory B cell longevity and repertoire composition
Cody, E. W., Ningoo, M., Monga, I., Tsankov, A. M., Muramatsu, H., Pardi, N., Fribourg, M., Heeger, P. S. & Dominguez-Sola, D., 6 Jul 2026, In: Journal of Experimental Medicine. 223, 7
Research output: Contribution to journal › Article › peer-review
Correction: Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer (Clin Cancer Res (2017), 23, (1552-1563), 10.1158/1078-0432.CCR-16-1333)
Chen, Y., Camacho, S. C., Silvers, T. R., Razak, A. R. A., Gabrail, N. Y., Gerecitano, J. F., Kalir, E., Pereira, E., Evans, B. R., Ramus, S. J., Huang, F., Priedigkeit, N., Rodriguez, E., Donovan, M., Khan, F., Kalir, T., Sebra, R., Uzilov, A., Chen, R. & Sinha, R. & 11 others, Halpert, R., Billaud, J. N., Shacham, S., McCauley, D., Landesman, Y., Rashal, T., Kauffman, M., Mirza, M. R., Mau-Sørensen, M., Dottino, P. & Martignetti, J. A., 15 Mar 2026, In: Clinical Cancer Research. 32, 6, p. 1183 1 p.
Research output: Contribution to journal › Comment/debate

Open Access

Lilly to present initial clinical data for first-in-class type II JAK2 inhibitor in patients with previously treated myelofibrosis at the 2026 EHA Annual Meeting
Mascarenhas, J.
12/06/26 → 13/06/26
22 items of Media coverage
Press/Media
Lilly To Present Initial Clinical Data For First-In-Class Type II JAK2 Inhibitor In Patients With Previously Treated Myelofibrosis At The 2026 EHA Annual Meeting
Mascarenhas, J.
13/06/26
4 items of Media coverage
Press/Media
Lilly to present initial clinical data for first-in-class type II JAK2 inhibitor in patients with previously treated myelofibrosis at the 2026 EHA Annual Meeting | LLY Stock News
Mascarenhas, J.
13/06/26
1 item of Media coverage
Press/Media
Incyte Announces New Positive Data at EHA 2026 Showed INCA033989 Achieved Rapid, Robust and Sustained Clinical and Molecular Responses and Was Well Tolerated in Patients with Myelofibrosis and Essential Thrombocythemia
Mascarenhas, J.
13/06/26
21 items of Media coverage
Press/Media
Cancer-Associated Mutations in Brain Immune Cells May Contribute to Alzheimer's Disease
Papapetrou, E. & Marro, S.
11/06/26 → 13/06/26
6 items of Media coverage
Press/Media
Lilly unveils first clinical data behind $2.3B Ajax deal, showing JAK inhibitor works ‘right out of the gate'
Mascarenhas, J.
13/06/26
2 items of Media coverage
Press/Media
Age-Related Mutations in Brain Immune Cells Linked to Alzheimer’s Inflammation
Papapetrou, E. & Marro, S.
13/06/26
1 item of Media coverage
Press/Media
Mount Sinai Scientists Reverse Aging in Blood Stem Cells by Fixing the Cell's Recycling System
Ghaffari, S.
12/06/26
1 item of Media coverage
Press/Media
Purple Biotech Presents New Preclinical Data at EACR 2026 Highlighting IM1240's Anti-Tumor Activity, Favorable Safety and Pharmacokinetic Profile, and Broad Therapeutic Window
Horowitz, A.
11/06/26
1 item of Media coverage
Press/Media
Reports Summarize Nanobodies Findings from Icahn School of Medicine at Mount Sinai (Multispecific nanobody degraders co-deplete membrane receptors and enable targeted delivery of diverse payloads)
Kabir, M., Zhong, Y., Huang, K. & Guccione, E.
11/06/26
1 item of Media coverage
Press/Media
Purple Biotech Presents New Preclinical Data At EACR 2026 Highlighting IM1240's Anti-Tumor Activity, Favorable Safety And Pharmacokinetic Profile, And Broad Therapeutic Window
Horowitz, A.
11/06/26
9 items of Media coverage
Press/Media
Methods of Monitoring Inflammatory Bowel Diseases
Özbek, U., Ungaro, R., Levine, J., Ferrara, J. & Colombel, J.-F.
9/06/26
1 item of Media coverage
Press/Media