Cardiovascular Research Institute

Projects

Projects per year 1986 2017 2018 2019 2024

• 27 Active
• 89 Finished

Projects per year

Search results

• Active

  Comprehensive genomic and inflammatory profiling of vaccine-associated myocarditis

  Kontorovich, A.

  National Institute of Allergy and Infectious Diseases

  3/11/22 → 31/10/23

  Project: Research

  • Myocarditis 100%
  • Human Genetics 81%
  • Vaccines 66%
  • Genetic Variation 64%
  • Cardiac Myocytes 62%

• Congenital Heart Disease Expert Curation Panel

  Roberts, A. A. E. & Gelb, B.

  National Institute of Child Health and Human Development

  1/08/22 → 30/06/23

  Project: Research

  • Congenital Heart Defects 100%
  • Heart Diseases 37%
  • Genes 22%
  • Genetic Testing 18%
  • Bicuspid Aortic Valve 8%

• Role of Epac1 in the Pathogenesis of Pulmonary Fibrosis

  Hadri, L.

  National Heart, Lung, and Blood Institute

  1/04/22 → 31/03/23

  Project: Research

  • Idiopathic Pulmonary Fibrosis 100%
  • Pulmonary Fibrosis 90%
  • Fibroblasts 34%
  • Lung Diseases 32%
  • Fibrosis 31%

• Identification of CaMKII as a novel substrate of dopaminylation following heroin self administration

  Stewart, A.

  National Institute on Drug Abuse

  19/01/22 → 18/01/24

  Project: Research

  • Substance-Related Disorders 100%
  • Calcium-Calmodulin-Dependent Protein Kinase Type 2 96%
  • Self Administration 90%
  • Heroin 86%
  • Dopamine 63%

• Circulating Extracellular Vesicles in the Pathogenesis of Type 1 Diabetes

  Vasavada, R. R. C., Sahoo, S., Sahoo, S. S. & Vasavada, R.

  National Institute of Diabetes and Digestive and Kidney Diseases

  24/08/21 → 31/05/23

  Project: Research

  • Extracellular Vesicles 100%
  • Type 1 Diabetes Mellitus 71%
  • Early Diagnosis 22%
  • Research Subjects 17%
  • Preliminary Data 15%

• DREAM Complex Maintenance of Human Beta Cell Quiescence

  Stewart, A. A. F., Wang, P. P., Stewart, A. & Wang, P.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/07/21 → 31/05/23

  Project: Research

  • Cell Proliferation 100%
  • Psychological Inhibition 82%
  • Insulinoma 63%
  • Transforming Growth Factor beta 46%
  • Chromatin 44%

• Influence of sleep on the hematopoietic niche and atherosclerosis during aging

  McAlpine, C. & Mcalpine, C. S.

  National Heart, Lung, and Blood Institute

  1/07/21 → 31/05/23

  Project: Research

  • Sleep 100%
  • Atherosclerosis 63%
  • Orexins 40%
  • Sleep Deprivation 36%
  • Cardiovascular Diseases 29%

• Influence of sleep on hematopoietic stem cell diversity and clonality in cardiovascular disease

  McAlpine, C. & Mcalpine, C. S.

  National Heart, Lung, and Blood Institute

  1/06/21 → 31/05/23

  Project: Research

  • Hematopoietic Stem Cells 100%
  • Sleep 71%
  • Cardiovascular Diseases 43%
  • Hematopoiesis 35%
  • Sleep Deprivation 30%

• Uncovering early signals of hereditary TTR amyloidosis in minority populations at high genetic risk

  Abul-Husn, N., Abul-husn, N. S., Kontorovich, A. A. R. & Kontorovich, A.

  National Heart, Lung, and Blood Institute

  1/04/21 → 31/03/23

  Project: Research

  • Familial Amyloidosis 100%
  • Hispanic Americans 21%
  • Amyloidosis 18%
  • Population 17%
  • TimeLine 16%

• Immune mechanisms of influenza A virus-induced susceptibility to myocardial infarction

  Downey, J. J. & Swirski, F.

  Institute of Infection and Immunity

  1/03/21 → 29/02/24

  Project: Research

  • Human Influenza 100%
  • Influenza A virus 86%
  • Myocardial Infarction 86%
  • Cardiovascular Diseases 47%
  • Monocytes 36%

• MerTK in NASH-related liver fibrosis

  Cai, B. & Cai, B.

  National Institute of Diabetes and Digestive and Kidney Diseases

  16/07/20 → 30/04/23

  Project: Research

  • Non-alcoholic Fatty Liver Disease 100%
  • Liver Cirrhosis 90%
  • Fibrosis 68%
  • Hepatic Stellate Cells 43%
  • Palmitic Acid 25%

• Understanding the Molecular Mechanisms of Fibromuscular Dysplasia

  Kadian-Dodov, D. L., Kovacic, J. J. C. & Kovacic, J.

  National Heart, Lung, and Blood Institute

  15/05/20 → 30/04/23

  Project: Research

  • Fibromuscular Dysplasia 100%
  • Gene Regulatory Networks 69%
  • Blood Vessels 14%
  • Phenotype 11%
  • Fibroblasts 9%

• ISS: Microphysiologic Model of Human Cardiovascular Stiffness-Related Diseases in Microgravity

  Costa, K. & Sachs, D.

  National Science Foundation

  1/09/19 → 31/08/23

  Project: Research

  • Weightlessness 100%
  • Cardiovascular Models 77%
  • Organoids 47%
  • Cardiovascular System 47%
  • Astronauts 33%

• Hematopoiesis in cardiovascular disease

  Nahrendorf, M. M., Lin, C. C. P., Scadden, D. D. T., Swirski, F. F. K., Joung, J. J. K., Joung, K. J., Naxerova, K. K., Lin, C. P., Nahrendorf, M., Scadden, D. T. & Swirski, F.

  1/08/19 → 31/07/23

  Project: Research

  • Hematopoiesis 100%
  • Leukocytosis 25%
  • Myocardial Infarction 25%
  • Hematopoietic Stem Cells 22%
  • Inflammation 20%

• Deciphering the Neonatal Cardiac Regenerative Potential and Regulators in Large Animals

  Zhang, J. J., Sadek, H. H., Zangi, L., Sadek, H. & Zhang, J.

  National Heart, Lung, and Blood Institute

  15/07/19 → 30/06/23

  Project: Research

  • Cell Cycle Checkpoints 100%
  • Muscle Cells 94%
  • Mammals 90%
  • Heart 83%
  • Heart Diseases 83%

• Project 3: Remote control of hematopoiesis in cardiovascular disease

  Swirski, F. F. K. & Swirski, F.

  National Heart, Lung, and Blood Institute

  1/07/19 → 31/07/23

  Project: Research

  • remote control 100%
  • hematopoiesis 87%
  • cardiovascular diseases 75%
  • bone marrow 73%
  • Hematopoiesis 37%

• AAV-Exosomes: Escaping Neutralizing Antibody and Enhancing Delivery

  Sahoo, S. & Sahoo, S.

  National Heart, Lung, and Blood Institute

  1/07/19 → 30/06/23

  Project: Research

  • Exosomes 100%
  • Neutralizing Antibodies 69%
  • Genes 20%
  • Heart Failure 14%
  • Genetic Therapy 13%

• SPACE RELEVANT RADIATION-INDUCED CARDIOVASCULAR DISEASE RISK THRESHOLDS: EFFECT OF GENDER ON THE OUTCOME

  Goukassian, D.

  Johnson Space Center

  10/04/19 → …

  Project: Research

  • Radiation 100%
  • Cardiovascular Diseases 80%
  • United States National Aeronautics and Space Administration 34%
  • Radiation Exposure 25%
  • Theoretical Models 19%

• Elucidation of the role of human genetic factors underlying viral myocarditis susceptibility

  Kontorovich, A. A. R. & Kontorovich, A.

  National Heart, Lung, and Blood Institute

  6/07/18 → 30/06/23

  Project: Research

  • Myocarditis 100%
  • Human Genetics 92%
  • Mentors 33%
  • Virology 23%
  • RNA Viruses 20%

• PET nanoreporter image-guided breast cancer therapy

  Fayad, Z., Pérez-medina, C. C., Fayad, Z. A., Grimm, J. J., Mulder, W., Perez-Medina, C. & Reiner, T.

  National Cancer Institute

  15/06/18 → 31/05/23

  Project: Research

  • Nanomedicine 100%
  • Positron-Emission Tomography 68%
  • Breast Neoplasms 46%
  • liposomal doxorubicin 39%
  • Technology 33%

• Cardiomyocyte-specific modified mRNA of Pkm2 for induction of cardiac regeneration in ischemic heart failure

  Zangi, L.

  National Heart, Lung, and Blood Institute

  1/06/18 → 31/05/23

  Project: Research

  • Regeneration 100%
  • Cardiac Myocytes 97%
  • Heart Failure 83%
  • Messenger RNA 68%
  • Genetic Therapy 55%

• Increasing Ischemic Myocardial Tissue Perfusion by Mechanical LV Support

  Ishikawa, K. K. & Ishikawa, K.

  National Heart, Lung, and Blood Institute

  15/12/17 → 30/11/23

  Project: Research

  • Cardiogenic Shock 100%
  • Hemodynamics 57%
  • Heart-Assist Devices 38%
  • Clinical Studies 30%
  • Equipment and Supplies 27%

• DYRK Inhibitors for Human Beta Cell Expansion

  Stewart, A., Garcia-ocana, A. A., Devita, R. J., García-Ocaña, A., DeVita, R. & Stewart, A. F.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/03/16 → 31/05/23

  Project: Research

  • Harmine 100%
  • National Institute of Diabetes and Digestive and Kidney Diseases (U.S.) 60%
  • Libraries 41%
  • Cell Proliferation 33%
  • Small Molecule Libraries 32%

• SYSTEMIC INFLAMMATORY NETWORKS IN ALZHEIMER'S DISEASE

  Swirski, F. & Nahrendorf, M. M.

  Cure Alzheimer's Fund

  1/01/15 → …

  Project: Research

  • Alzheimer Disease 100%
  • Inflammation 58%
  • Dementia 33%
  • Organized Financing 23%
  • Symptom Flare Up 22%

• The Effect of Aging on DNA Repair and Mutation Rate: Modulation by DNA Oligonucleotide Therapy

  Goukassian, D.

  American Federation for Aging Research

  1/01/00 → …

  Project: Research

• Training Program in Molecular and Cellular Cardiology

  Gelb, B. B. D., Gelb, B., Hajjar, R., Kovacic, J. & Taubman, M. M. B.

  National Heart, Lung, and Blood Institute

  1/07/95 → 31/07/23

  Project: Research

  • Cardiology 100%
  • Education 63%
  • Translational Medical Research 35%
  • Research Personnel 29%
  • Physicians 22%

• T32 Research Training in Diabetes and Endocrinology

  O'doherty, R. R. M., Robinson, A. A. G., Stewart, A., Derubertis, F. F. R., Goodpaster, B. H., O'doherty, R. M. & Stewart, A. F.

  National Institute of Diabetes and Digestive and Kidney Diseases

  1/07/86 → 30/06/23

  Project: Research

  • endocrinology 100%
  • diabetes 82%
  • chronic illness 62%
  • mentoring 58%
  • trainee 33%