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Cancer Clinical Investigation

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  • A convergent uPAR-positive tumor ecosystem creates broad vulnerability to CAR T cell therapy

    Zhang, Z., Ho, Y. J., Fang, X., Kim, M., Li, M., Luan, W., Hinterleitner, C., Haubner, S., Kogel, F., Pratt, E. C., Ozcelik, E., Reyes, J., Jiang, Q., Yang, V. W., Chen, Y. J., Wang, T., Liu, H., Hu, H., Zhuang, X. & Park, J. & 48 others, Paffenholz, S. V., Chen, K., Chang, Q., Kulick, A., Zhang, J., Chan, E., Rosiek, E., Fan, N., Williams, R. A., Wang, A. C., Freeman, S., Tian, S., Gunset, G., Garcia Angus, A., Lecomte, N., Yildirim, S. Y., Ali, E., Wu, M., Miranda, I. C., Antonescu, C. R., Basturk, O., Tarcan, Z., Rekhtman, N., Wilson, C., Basar, M., Sauter, J. L., Al-Ahmadie, H. A., Singer, S., Iacobuzio-Donahue, C., Rudin, C., de Stanchina, E., Ganesh, K., Romesser, P. B., Weigelt, B., Huh, D. D., Leibold, J., Feucht, J., Vázquez-García, I., Bott, M. J., Zamarin, D., Shah, S. P., Lewis, J. S., Amor, C., Pe’er, D., Mansilla-Soto, J., Filliol, A., Sadelain, M. & Lowe, S. W., 2026, (Accepted/In press) In: Cell.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Activated ATF6α is a hepatic tumour driver restricting immunosurveillance

    Li, X., Lebeaupin, C., Kadianaki, A., Druelle-Cedano, C., Vesper, N., Rennert, C., Huguet-Pradell, J., Gomez Ramos, B., Fan, C., Piecyk, R. S., Zizmare, L., Ramadori, P., Li, L., Frick, L., Qiu, M., Zhang, C., Martins Nascentes Melo, L., Ranvir, V. P., Shen, P. & Hanselmann, J. & 78 others, Kosla, J., Fernández-Vaquero, M., Vucur, M., Baskaran, P., Bao, X., Coleman, O. I., Tang, Y., Cetin, M., Chen, Z., Jang, I., Del Prete, S., Rahbari, M., Zhang, P., Pham, T. V., Hou, Y., Sun, A., Gu, L., Kim, L. C., Rothermel, U., Heide, D., Ali, A., Gallage, S., Talvard-Balland, N., Piqué-Gili, M., Gris-Oliver, A., Bevilacqua, A., Schlicker, L., Duffey, A., Unger, K., Szydlowska, M., Hetzer, J., Odom, D. T., Machauer, T., Bucci, D., Sant, P., Lee, J. H., Rösler, J., Meckelmann, S. W., Schreck, J., Murray, S., Simon, M. C., Nahnsen, S., Schulze, A., Ho, P. C., Jugold, M., Breuhahn, K., Mallm, J. P., Schirmacher, P., Roth, S., Rahbari, N., Tschaharganeh, D. F., Roessler, S., Goeppert, B., Bengsch, B., Andrieux, G., Boerries, M., Malek, N. P., Prinz, M., Weber, A., Zeiser, R., Tamayo, P., Bronsert, P., Kurowski, K., Thimme, R., Yuan, D., Carretero, R., Luedde, T., Pinyol, R., Hartmann, F. J., Karin, M., Tasdogan, A., Trautwein, C., Mall, M., Hofmann, M., Llovet, J. M., Haller, D., Kaufman, R. J. & Heikenwälder, M., 19 Mar 2026, In: Nature. 651, 8106, p. 796-807 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • Adjuvant nivolumab versus placebo for high-risk muscle-invasive urothelial carcinoma: 5-year efficacy and ctDNA results from CheckMate 274☆

    Galsky, M. D., Gschwend, J. E., Milowsky, M. I., Schenker, M., Valderrama, B. P., Tomita, Y., Bamias, A., Lebret, T., Shariat, S. F., Park, S. H., Agerbaek, M., Jha, G., Stenner, F., Ye, D., Giudici, F., Connors, J., Gupta, S., Chhibber, A., Zhang, J. & Bajorin, D. F. & 1 others, Witjes, J. A., Jan 2026, In: Annals of Oncology. 37, 1, p. 69-78 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Advanced Urologic Cancer Consensus Conference (AUC3) 2025: Expert consensus on the management of renal cell and urinary tract cancers

    McKay, R. R., Pal, S., Xie, W., Aggen, D., Albiges, L., Apolo, A., Atkins, M. B., Bangs, R., Beckermann, K. E., Bellmunt, J., Berg, S. A., Bilen, M. A., Braun, D., Carlo, M. I., Efstathiou, J., Galsky, M., Grivas, P., Gupta, S., Haas, N. & Hakimi, A. A. & 34 others, Hammers, H., Heng, D. Y. C., Hirsch, M., Iyer, G., Jonasch, E., Koshkin, V. S., Kryvenko, O., Lewis, B., Li, R., Matin, S., Maughan, B., McDermott, D. F., McGregor, B., Meeks, J., Milowsky, M., Motzer, R., Necchi, A., Petrylak, D., Porten, S., Powles, T., Rini, B., Shuch, B., Siefker-Radtke, A., Sonpavde, G., Sridhar, S. S., Suarez, C., Tang, C., Tripathi, A., Van Der Heijden, M. S., Voss, M., Xu, W., Zhang, T., Rosenberg, J. & Choueiri, T. K., 1 Jan 2026, In: Ca-A Cancer Journal for Clinicians. 76, 1, e70052.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    1 Scopus citations

  • Advances in Imaging and Diagnosis of Emphysematous Cholecystitis

    Miao, K. H., Miao, J. H., Rosberger, S., Dachman, A. H., Taouli, B. & Lewis, S. C., Mar 2026, In: Healthcare (Switzerland). 14, 5, 617.

    Research output: Contribution to journal › Review article › peer-review

    Open Access

  • A gated hydrophobic funnel within BAX binds bioactive lipids to potentiate pro-apoptotic function

    Gelles, J. D., Chen, Y., Luna-Vargas, M. P. A., Viacava Follis, A., Al Noman, M. A., Kabir, M., Bayiokos, S. G., Mohammed, J. N., Sebastian, T. M., Pham, N. D., Shi, Y., Jin, J., Kriwacki, R. W. & Chipuk, J. E., Dec 2026, In: Nature Communications. 17, 1, 3180.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • A GPX1-OSBPL8 axis mediates noncanonical in vivo ferroptosis and cancer growth suppression

    Xia, Z., Yang, X., Samovich, S. N., Tyurina, Y. Y., Tyurin, V. A., Kon, N., Zhang, J., Jiang, X., Stockwell, B. R., Jin, J., Bayir, H., Kagan, V. E. & Gu, W., 2 Apr 2026, In: Cell. 189, 7, p. 1957-1974.e17

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • A highly promising new avenue for targeting K-RAS: The small-molecule degrader XMU-MP-9

    Jin, J., Feb 2026, In: Acta Pharmaceutica Sinica B. 16, 2, p. 1166-1167 2 p.

    Research output: Contribution to journal › Editorial

    Open Access

  • An ethical framework for managing neglected skin tumors in older patients

    Thakker, S., Minkis, K., Lipner, S. R., Gulati, N., Patel, V. A. & Al-Mondhiry, J., Jan 2026, In: Journal of the American Academy of Dermatology. 94, 1, p. 395-396 2 p.

    Research output: Contribution to journal › Letter › peer-review

  • Anti–B-cell Maturation Antigen Chimeric Antigen Receptor T-cell Therapy bb21217 for Relapsed and Refractory Multiple Myeloma: Results from the Phase I CRB-402 Study

    Alsina, M., Shah, N., Jagannath, S., Kaufman, J. L., Siegel, D., Munshi, N. C., Rosenblatt, J., Lin, Y., Jakubowiak, A. J., Derman, B. A., Li, A., Mao, P., Fincker, M., Yeri, A., Martin, N., Campbell, T. B., Finney, O., Truppel-Hartmann, A., Petrocca, F. & Berdeja, J. G. & 1 others, Raje, N., 1 Apr 2026, In: Cancer Immunology Research. 14, 4, p. 528-542 15 p.

    Research output: Contribution to journal › Article › peer-review

  • A Phase II Trial of an Extended-Release siRNA Implant Targeting KRASG12D/V in Locally Advanced Pancreatic Cancer

    Alagesan, B., Varghese, A. M., Ang, C., Gutierrez, M., Kamar, M., Passhak, M., Geva, R., Yarom, N., Lahav, M., Ligresti, R., Khamaysi, I., Bhutani, M. S., Phillips, A., Matalon, S., Pollack-Shragai, O., Rom, D., Shirvan, M., Javle, M. M., Park, W. & Yu, K. & 4 others, Schwartz, C., Golan, T., Schattner, M. & Oreilly, E. M., 15 Mar 2026, In: Clinical Cancer Research. 32, 6, p. 1059-1067 9 p.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • A Phase II Trial to Evaluate the Safety and Immunogenicity of Two Doses of a Folate Receptor Alpha Vaccine in Patients with Triple-Negative Breast Cancer

    Knutson, K. L., Abu-Fares, H., Keating, P., Block, M. S., Norton, N., Erskine, C. L., Cogen, D., Assad, H., Graff, S. L., Hamilton, E. P., Han, H. S., McIntyre, K. J., Nassar, A., Sparano, J. A., Tiersten, A., Tkaczuk, K. H., Ward, P. J., Wilson, G., Garrett, G. & Kenney, R. T. & 1 others, Sharma, P., 1 Jan 2026, In: Clinical Cancer Research. 32, 1, p. 106-117 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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