Cancer Biology

41 Active
99 Finished

Chronic Mitochondrial Division and Melanoma: Mechanism, Prognosis, and Therapy
Chipuk, J.
National Cancer Institute
15/07/22 → 31/05/23
Project: Research
Skin Biology and Diseases Resource-based Center at Mount Sinai
Ezhkova, E., Bowcock, A. A. M., Bowcock, A. M., Ezhkova, E., Guccione, E. E., Guccione, E., Rendl, M. & Rendl, M.
National Institute of Arthritis and Musculoskeletal and Skin Diseases
1/09/21 → 31/08/23
Project: Research
FUNCTIONAL CHARACTERIZATION OF THE PRDM10-ZN FINGER TRANSCRIPTION FACTOR IN EARLY MAMMALIAN DEVELOPMENT
Guccione, E. & Guccione, E.
National Institute of Child Health and Human Development
31/08/21 → 30/04/23
Project: Research
Resource Core D - Bioinformatics and Statistical Analysis Core
Guccione, E. & Guccione, E. E.
National Institute of Arthritis and Musculoskeletal and Skin Diseases
1/07/21 → 31/08/23
Project: Research
AN INTEGRATED PLATFORM FOR NOVEL PERSONALIZED LIVER CANCER THERAPEUTICS
Dar, A., Guccione, E., Lujambio, A., Guccione, E. E., Guccione, E. & Lujambio, A.
National Cancer Institute
1/07/21 → 30/06/23
Project: Research
A Chemical Genetic Approach to Exploring Novel Therapeutic Space for Colorectal Cancer
Dar, A., Cagan, R., Dar, A. & Cagan, R. R. L.
National Cancer Institute
1/03/21 → 28/02/23
Project: Research
IND-Enabling Studies for WNTinib, a Novel Selective Therapeutic for CTNNB1 Mutant Hepatoblastomas
Guccione, E., Llovet, J. J. & Dar, A.
Alex's Lemonade Stand Foundation for Childhood Cancer
1/01/21 → …
Project: Research
DISSECTING THE ROLE OF PRDM15 IN NORMAL HEMATOPOIESIS AND B-CELL MALIGNANCIES
Guccione, E. & Guccione, E.
National Cancer Institute
9/12/20 → 30/11/23
Project: Research
Cell lineage determinants of p53-driven fate outcomes in vivo
Manfredi, J., Prives, C. C., Manfredi, J. J. & Prives, C.
National Cancer Institute
9/12/20 → 30/11/23
Project: Research
Developmental Funds
Parsons, R. E. & Parsons, R.
National Cancer Institute
1/08/20 → 31/07/23
Project: Research
Leadership, Planning and Evaluation
Parsons, R.
National Cancer Institute
1/08/20 → 31/07/23
Project: Research
Flow Cytometry
Ochando, J. & Ochando, J. J.
National Cancer Institute
1/08/20 → 31/07/23
Project: Research

44551 Citations
104 h-index
530 Article
91 Review article
32 Comment/debate
26 Chapter
More

Cutting Edge: Neutrophil Complement Receptor Signaling Is Required for BAFF-Dependent Humoral Responses in Mice
Cumpelik, A., Cody, E., Yu, S. M. W., Grasset, E. K., Dominguez-Sola, D., Cerutti, A. & Heeger, P. S., 1 Jan 2023, In: Journal of Immunology. 210, 1, p. 19-23 5 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Trained immunity — basic concepts and contributions to immunopathology
Ochando, J., Mulder, W. J. M., Madsen, J. C., Netea, M. G. & Duivenvoorden, R., Jan 2023, In: Nature Reviews Nephrology. 19, 1, p. 23-37 15 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
A kinetic fluorescence polarization ligand assay for monitoring BAX early activation
Gelles, J. D., Mohammed, J. N., Chen, Y., Sebastian, T. M. & Chipuk, J. E., 28 Mar 2022, In: Cell Reports Methods. 2, 3, 100174.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma
Zhou, R. W., Xu, J., Martin, T. C., Zachem, A. L., He, J., Ozturk, S., Demircioglu, D., Bansal, A., Trotta, A. P., Giotti, B., Gryder, B., Shen, Y., Wu, X., Carcamo, S., Bosch, K., Hopkins, B., Tsankov, A., Steinhagen, R., Jones, D. R., Asara, J., & 7 othersChipuk, J. E., Brody, R., Itzkowitz, S., Chio, I. I. C., Hasson, D., Bernstein, E. & Parsons, R. E., Dec 2022, In: Nature Communications. 13, 1, 6041.
Research output: Contribution to journal › Article › peer-review

Open Access
Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
Carcamo, S., Nguyen, C. B., Grossi, E., Filipescu, D., Alpsoy, A., Dhiman, A., Sun, D., Narang, S., Imig, J., Martin, T. C., Parsons, R., Aifantis, I., Tsirigos, A., Aguirre-Ghiso, J. A., Dykhuizen, E. C., Hasson, D. & Bernstein, E., 5 Apr 2022, In: Cell Reports. 39, 1, 110637.
Research output: Contribution to journal › Article › peer-review

Open Access
3 Scopus citations
An Antagonist of KSR1-Driven Adaptive Resistance to Clinical RAS-MAPK Inhibitors
Chow, A., Yerabolu, J. R., Reyes, K., Scopton, A. & Dar, A. C., 1 May 2022, In: FASEB Journal. 36
Research output: Contribution to journal › Article › peer-review

Open Access
An interplay between BRD4 and G9a regulates skeletal myogenesis
Yang, N., Das, D., Shankar, S. R., Goy, P. A., Guccione, E. & Taneja, R., 7 Sep 2022, In: Frontiers in Cell and Developmental Biology. 10, 978931.
Research output: Contribution to journal › Article › peer-review

Open Access
Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets
Xiong, Y., Zhong, Y., Yim, H., Yang, X., Park, K. S., Xie, L., Poulikakos, P. I., Han, X., Xiong, Y., Chen, X., Liu, J. & Jin, J., 14 Dec 2022, In: Journal of the American Chemical Society. 144, 49, p. 22622-22632 11 p.
Research output: Contribution to journal › Article › peer-review
CDK4: a master regulator of the cell cycle and its role in cancer
Baker, S. J., Poulikakos, P. I., Irie, H. Y., Parekh, S. & Reddy, E. P., 2022, In: Genes and Cancer. 13, p. 21-45 25 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
Cellular and Humoral Responses Follow-up for 8 Months after Vaccination with mRNA-Based Anti-SARS-CoV-2 Vaccines
Gil-Manso, S., Carbonell, D., Pérez-Fernández, V. A., López-Esteban, R., Alonso, R., Muñoz, P., Ochando, J., Sánchez-Arcilla, I., Bellón, J. M., Correa-Rocha, R. & Pion, M., Jul 2022, In: Biomedicines. 10, 7, 1676.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Conformational control and regulation of the pseudokinase KSR via small molecule binding interactions
Chow, A., Khan, Z. M., Marsiglia, W. M. & Dar, A. C., Jan 2022, Pseudokinases. Jura, N. & Murphy, J. M. (eds.). Academic Press Inc., p. 365-402 38 p. (Methods in Enzymology; vol. 667).
Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
Correlation between BAP1 Localization, Driver Mutations, and Patient Survival in Uveal Melanoma
Cole, Y. C., Zhang, Y. Z., Gallo, B., Januszewski, A. P., Nastase, A., Essex, D. J., Thaung, C. M. H., Cohen, V. M. L., Sagoo, M. S. & Bowcock, A. M., Sep 2022, In: Cancers. 14, 17, 4105.
Research output: Contribution to journal › Article › peer-review

Open Access

US Patent Issued to Icahn School of Medicine at Mount Sinai on Jan. 3 for "Compositions and methods for treating CDK4/6-mediated cancer" (New York, New Jersey Inventors)
Tamer Ahmed, Zoi Karoulia, XUEWEI WU , Yan Xiong , Poulikos Poulikakos, Jing Liu & Jian Jin
21/01/23
1 item of Media coverage
Press/Media
C. David Allis, pioneer of chromatin biology and epigenetics, dies at 71
Emily Bernstein
20/01/23
1 item of Media coverage
Press/Media
A Statement From Scientists On The Use And Threats Of Use Of Nuclear Weapons
David Wolfe, Robert Fisher, David Cohen & Jeffrey Johnson
17/01/23
1 item of Media coverage
Press/Media
Uncovering the Real Story Behind the ‘East Bay Mystery Walls’
Robert Fisher
12/01/23
1 item of Media coverage
Press/Media
U.S. Patents Awarded to Inventors in New Jersey (Jan. 5)
Tamer Ahmed, Zoi Karoulia, XUEWEI WU , Yan Xiong , Yang Yang, Poulikos Poulikakos, Jing Liu & Jian Jin
5/01/23
1 item of Media coverage
Press/Media
U.S. Patents Awarded to Inventors in New York (Jan. 5)
Tamer Ahmed, Zoi Karoulia, XUEWEI WU , Yan Xiong , Arvind Kumar, Poulikos Poulikakos, Jing Liu & Jian Jin
5/01/23
1 item of Media coverage
Press/Media
Compositions and Methods for Treating CDK4/6-mediated Cancer
Tamer Ahmed, Zoi Karoulia, XUEWEI WU , Yan Xiong , Poulikos Poulikakos, Jing Liu & Jian Jin
3/01/23
1 item of Media coverage
Press/Media
Sylvester Attracts World’s Top Epigenetics Experts for Fifth Biennial Miami Epigenetics and Cancer Symposium
Emily Bernstein
22/12/22
1 item of Media coverage
Press/Media
SYLVESTER ATTRACTS WORLD'S TOP EPIGENETICS EXPERTS FOR FIFTH BIENNIAL MIAMI EPIGENETICS AND CANCER SYMPOSIUM
Emily Bernstein
19/12/22
1 item of Media coverage
Press/Media
CDK4: A master regulator of the cell cycle and its role in cancer
E. Premkumar Reddy, Poulikos Poulikakos, Stacey Baker & Samir Parekh
5/12/22
3 items of Media coverage
Press/Media
Master regulator of cell cycle and its role in cancer
E. Premkumar Reddy, Poulikos Poulikakos, Stacey Baker & Samir Parekh
3/12/22
1 item of Media coverage
Press/Media
U.S. Patents Awarded to Inventors in New York (Dec. 2)
ANQI MA , Michael Ohlmeyer, Dongming Cai, Ramon Parsons & Jian Jin
2/12/22
1 item of Media coverage
Press/Media