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  • 2017

    Excessive burden of lysosomal storage disorder gene variants in Parkinson's disease

    Robak, L. A., Jansen, I. E., Rooij, J. V., Uitterlinden, A. G., Kraaij, R., Jankovic, J., Heutink, P., Shulman, J. M., Nalls, M. A., Plagnol, V., Hernandez, D. G., Sharma, M., Sheerin, U. M., Saad, M., Simón-Sánchez, J., Schulte, C., Lesage, S., Sveinbjörnsdóttir, S., Arepalli, S., Barker, R., & 119 othersBen, Y., Berendse, H. W., Berg, D., Bhatia, K., de Bie, R. M. A., Biffi, A., Bloem, B., Bochdanovits, Z., Bonin, M., Bras, J. M., Brockmann, K., Brooks, J., Burn, D. J., Majounie, E., Charlesworth, G., Lungu, C., Chen, H., Chinnery, P. F., Chong, S., Clarke, C. E., Cookson, M. R., Cooper, J. M., Corvol, J. C., Counsell, C., Damier, P., Dartigues, J. F., Deloukas, P., Deuschl, G., Dexter, D. T., van Dijk, K. D., Dillman, A., Durif, F., Dürr, A., Edkins, S., Evans, J. R., Foltynie, T., Dong, J., Gardner, M., Gibbs, J. R., Goate, A., Gray, E., Guerreiro, R., Harris, C., van Hilten, J. J., Hofman, A., Hollenbeck, A., Holton, J., Hu, M., Huang, X., Wurster, I., Mätzler, W., Hudson, G., Hunt, S. E., Huttenlocher, J., Illig, T., Jónsson, P. V., Lambert, J. C., Langford, C., Lees, A., Lichtner, P., Limousin, P., Lopez, G., Lorenz, D., Lungu, C., McNeill, A., Moorby, C., Moore, M., Morris, H. R., Morrison, K. E., Escott-Price, V., Mudanohwo, E., O’sullivan, S. S., Pearson, J., Perlmutter, J. S., Pétursson, H., Pollak, P., Post, B., Potter, S., Ravina, B., Revesz, T., Riess, O., Rivadeneira, F., Rizzu, P., Ryten, M., Sawcer, S., Schapira, A., Scheffer, H., Shaw, K., Shoulson, I., Shulman, J., Sidransky, E., Smith, C., Spencer, C. C. A., Stefánsson, H., Bettella, F., Stockton, J. D., Strange, A., Talbot, K., Tanner, C. M., Tashakkori-Ghanbaria, A., Tison, F., Trabzuni, D., Traynor, B. J., Velseboer, D., Vidailhet, M., Walker, R., Warrenburg, B. V. D., Wickremaratchi, M., Williams, N., Williams-Gray, C. H., Winder-Rhodes, S., Stefánsson, K., Martinez, M., Wood, N. W., Hardy, J., Heutink, P., Brice, A., Gasser, T. & Singleton, A. B., 1 Dec 2017, In: Brain. 140, 12, p. 3191-3203 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    261 Scopus citations

  • Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score

    Desikan, R. S., Fan, C. C., Wang, Y., Schork, A. J., Cabral, H. J., Cupples, L. A., Thompson, W. K., Besser, L., Kukull, W. A., Holland, D., Chen, C. H., Brewer, J. B., Karow, D. S., Kauppi, K., Witoelar, A., Karch, C. M., Bonham, L. W., Yokoyama, J. S., Rosen, H. J., Miller, B. L., & 14 othersDillon, W. P., Wilson, D. M., Hess, C. P., Pericak-Vance, M., Haines, J. L., Farrer, L. A., Mayeux, R., Hardy, J., Goate, A. M., Hyman, B. T., Schellenberg, G. D., McEvoy, L. K., Andreassen, O. A. & Dale, A. M., Mar 2017, In: PLoS Medicine. 14, 3, e1002258.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    243 Scopus citations

  • Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology

    Monsell, S. E., Mock, C., Fardo, D. W., Bertelsen, S., Cairns, N. J., Roe, C. M., Ellingson, S. R., Morris, J. C., Goate, A. M. & Kukull, W. A., 2017, In: Alzheimer Disease and Associated Disorders. 31, 3, p. 232-238 7 p.

    Research output: Contribution to journal › Article › peer-review

    12 Scopus citations

  • Genetic correlation between amyotrophic lateral sclerosis and schizophrenia

    McLaughlin, R. L., Schijven, D., Van Rheenen, W., Van Eijk, K. R., O'Brien, M., Kahn, R. S., Ophoff, R. A., Goris, A., Bradley, D. G., Al-Chalabi, A., Van Den Berg, L. H., Luykx, J. J., Hardiman, O., Veldink, J. H., Shatunov, A., Dekker, A. M., Diekstra, F. P., Pulit, S. L., Van Der Spek, R. A. A., Van Doormaal, P. T. C., & 416 othersSproviero, W., Jones, A. R., Nicholson, G. A., Rowe, D. B., Pamphlett, R., Kiernan, M. C., Bauer, D., Kahlke, T., Williams, K., Eftimov, F., Fogh, I., Ticozzi, N., Lin, K., Millecamps, S., Salachas, F., Meininger, V., Carvalho, M. D., Pinto, S., Mora, J. S., Rojas-Garcyá, R., Polak, M., Chandran, S., Colville, S., Swingler, R., Morrison, K. E., Shaw, P. J., Hardy, J., Orrell, R. W., Pittman, A., Sidle, K., Fratta, P., Malaspina, A., Petri, S., Abdulla, S., Drepper, C., Sendtner, M., Meyer, T., Wiedau-Pazos, M., Lomen-Hoerth, C., Deerlin, V. M. V., Trojanowski, J. Q., Elman, L., McCluskey, L., Basak, N., Meitinger, T., Lichtner, P., Blagojevic-Radivojkov, M., Andres, C. R., Maurel, C., Bensimon, G., Landwehrmeyer, B., Brice, A., Payan, C. A. M., Saker-Delye, S., Durr, A., Wood, N., Tittmann, L., Lieb, W., Franke, A., Rietschel, M., Cichon, S., Nothen, M. M., Amouyel, P., Tzourio, C., Dartigues, J. F., Uitterlinden, A. G., Rivadeneira, F., Estrada, K., Hofman, A., Curtis, C., Derkooi, A. J. V., De Visser, M., Weber, M., Shaw, C. E., Smith, B. N., Pansarasa, O., Cereda, C., Bo, R. D., Comi, G. P., D'Alfonso, S., Bertolin, C., Soraru, G., Mazzini, L., Pensato, V., Gellera, C., Tiloca, C., Ratti, A., Calvo, A., Moglia, C., Brunetti, M., Arcuti, S., Capozzo, R., Zecca, C., Lunetta, C., Penco, S., Riva, N., Padovani, A., Filosto, M., Blair, I., Nigel Leigh, P., Casale, F., Chio, A., Beghi, E., Pupillo, E., Tortelli, R., Logroscino, G., Powell, J., Ludolph, A. C., Weishaupt, J. H., Robberecht, W., Damme, P. V., Brown, R. H., Glass, J., Landers, J. E., Andersen, P. M., Corcia, P., Vourc'H, P., Silani, V., Es, M. A. V., Pasterkamp, R. J., Lewis, C. M., Breen, G., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F., Bacanu, S. A., Begemann, M., Belliveau, R. A., Bene, J., Bergen, S. E., Bevilacqua, E., Bigdeli, T. B., Black, D. W., Bruggeman, R., Buccola, N. G., Buckner, R. L., Byerley, W., Cahn, W., Cai, G., Campion, D., Cantor, R. M., Carr, V. J., Carrera, N., Catts, S. V., Chambert, K. D., Chan, R. C. K., Chan, R. Y. L., Chen, E. Y. H., Cheng, W., Cheung, E. F. C., Chong, S. A., Cloninger, C. R., Cohen, D., Cohen, N., Cormican, P., Craddock, N., Crowley, J. J., Curtis, D., Davidson, M., Davis, K. L., Degenhardt, F., Favero, J. D., Demontis, D., Dikeos, D., Dinan, T., Djurovic, S., Donohoe, G., Drapeau, E., Duan, J., Dudbridge, F., Durmishi, N., Eichhammer, P., Eriksson, J., Escott-Price, V., Essioux, L., Fanous, A. H., Farrell, M. S., Frank, J., Franke, L., Freedman, R., Freimer, N. B., Friedl, M., Friedman, J. I., Fromer, M., Genovese, G., Georgieva, L., Giegling, I., Giusti-Rodrýguez, P., Godard, S., Goldstein, J. I., Golimbet, V., Gopal, S., Gratten, J., De Haan, L., Hammer, C., Hamshere, M. L., Hansen, M., Hansen, T., Haroutunian, V., Hartmann, A. M., Henskens, F. A., Herms, S., Hirschhorn, J. N., Hoffmann, P., Hofman, A., Hollegaard, M. V., Hougaard, D. M., Ikeda, M., Joa, I., Julia, A., Kalaydjieva, L., Karachanak-Yankova, S., Karjalainen, J., Kavanagh, D., Keller, M. C., Kennedy, J. L., Khrunin, A., Kim, Y., Klovins, J., Knowles, J. A., Konte, B., Kucinskas, V., Kucinskiene, Z. A., Kuzelova-Ptackova, H., Kahler, A. K., Laurent, C., Lee, J., Hong Lee, S., Legge, S. E., Lerer, B., Li, M., Li, T., Liang, K. Y., Lieberman, J., Limborska, S., Loughland, C. M., Lubinski, J., Lonnqvist, J., MacEk, M., Magnusson, P. K. E., Maher, B. S., Maier, W., Mallet, J., Marsal, S., Mattheisen, M., Mattingsdal, M., McCarley, R. W., McDonald, C., McIntosh, A. M., Meier, S., Meijer, C. J., Melegh, B., Melle, I., Mesholam-Gately, R. I., Metspalu, A., Michie, P. T., Milani, L., Milanova, V., Mokrab, Y., Morris, D. W., Mors, O., Murphy, K. C., Murray, R. M., Myin-Germeys, I., Muller-Myhsok, B., Nelis, M., Nenadic, I., Nertney, D. A., Nestadt, G., Nicodemus, K. K., Nikitina-Zake, L., Nisenbaum, L., Nordin, A., O'Callaghan, E., O'Dushlaine, C., Anthony O'Neill, F., Oh, S. Y., Olincy, A., Olsen, L., Vanos, J., Pantelis, C., Papadimitriou, G. N., Papiol, S., Parkhomenko, E., Pato, M. T., Paunio, T., Pejovic-Milovancevic, M., Perkins, D. O., Pietilainen, O., Pimm, J., Pocklington, A. J., Price, A., Pulver, A. E., Purcell, S. M., Quested, D., Rasmussen, H. B., Reichenberg, A., Reimers, M. A., Richards, A. L., Roffman, J. L., Roussos, P., Ruderfer, D. M., Salomaa, V., Sanders, A. R., Schall, U., Schubert, C. R., Schulze, T. G., Schwab, S. G., Scolnick, E. M., Scott, R. J., Seidman, L. J., Shi, J., Sigurdsson, E., Silagadze, T., Silverman, J. M., Sim, K., Slominsky, P., Smoller, J. W., So, H. C., Spencer, C. C. A., Stah, E. A., Stefansson, H., Steinberg, S., Stogmann, E., Straub, R. E., Strengman, E., Strohmaier, J., Scott Stroup, T., Subramaniam, M., Suvisaari, J., Svrakic, D. M., Szatkiewicz, J. P., Söderman, E., Thirumalai, S., Toncheva, D., Tosato, S., Veijola, J., Waddington, J., Walsh, D., Wang, D., Wang, Q., Webb, B. T., Weiser, M., Wildenauer, D. B., Williams, N. M., Williams, S., Witt, S. H., Wolen, A. R., Wong, E. H. M., Wormley, B. K., Xi, H. S., Zai, C. C., Zheng, X., Zimprich, F., Wray, N. R., Stefansson, K., Visscher, P. M., Adolfsson, R., Andreassen, O. A., Blackwood, D. H. R., Bramon, E., Buxbaum, J. D., Børglum, A. D., Darvasi, A., Domenici, E., Ehrenreich, H., Esko, T., Gejman, P. V., Gil, M., Gurling, H., Hultman, C. M., Iwata, N., Jablensky, A. V., Jonsson, E. G., Kendler, K. S., Kirov, G., Knight, J., Lencz, T., Levinson, D. F., Li, Q. S., Liu, J., Malhotra, A. K., McCarrol, S. A., McQuillin, A., Moran, J. L., Mortensen, P. B., Mowry, B. J., Owen, M. J., Palotie, A., Pato, C. N., Petryshen, T. L., Posthuma, D., Riley, B. P., Rujescu, D., Sham, P. C., Sklar, P., Clair, D. S., Weinberger, D. R., Wendland, J. R., Werge, T., Daly, M. J., Sullivan, P. F. & O'Donovan, M. C., 21 Mar 2017, In: Nature Communications. 8, 14774.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    88 Scopus citations

  • Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

    Alzheimer’s Disease Neuroimaging Initiative (ADNI) & The Alzheimer Disease Genetic Consortium (ADGC), 1 May 2017, In: Acta Neuropathologica. 133, 5, p. 839-856 18 p.

    Research output: Contribution to journal › Article › peer-review

    139 Scopus citations

  • Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

    Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 2017, In: Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

    Research output: Contribution to journal › Article › peer-review

    36 Scopus citations

  • Gradients in cytoarchitectural landscapes of the isocortex: Diprotodont marsupials in comparison to eutherian mammals

    Charvet, C. J., Stimpson, C. D., Kim, Y. D., Raghanti, M. A., Lewandowski, A. H., Hof, P. R., Gómez-Robles, A., Krienen, F. M. & Sherwood, C. C., 1 Jun 2017, In: Journal of Comparative Neurology. 525, 8, p. 1811-1826 16 p.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations

  • Haptoglobin 1-1 genotype modulates the association of glycemic control with hippocampal volume in elderly individuals with type 2 diabetes

    Livny, A., Ravona-Springer, R., Heymann, A., Priess, R., Kushnir, T., Tsarfaty, G., Rabinov, L., Moran, R., Tik, N., Moshier, E., Cooper, I., Greenbaum, L., Silverman, J., Levy, A., Sano, M., Bendlin, B. B., Buchman, A. S. & Schnaider-Beeri, M., 1 Nov 2017, In: Diabetes. 66, 11, p. 2927-2932 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Hemoglobin A1c variability predicts symptoms of depression in elderly individuals with type 2 diabetes

    Ravona-Springer, R., Heymann, A., Schmeidler, J., Moshier, E., Guerrero-Berroa, E., Soleimani, L., Sano, M., Leroith, D., Preiss, R., Tzukran, R., Silverman, J. M. & Beeri, M. S., 1 Sep 2017, In: Diabetes Care. 40, 9, p. 1187-1193 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • Impact of the REACH II and REACH VA Dementia Caregiver Interventions on Healthcare Costs

    Nichols, L. O., Martindale-Adams, J., Zhu, C. W., Kaplan, E. K., Zuber, J. K. & Waters, T. M., May 2017, In: Journal of the American Geriatrics Society. 65, 5, p. 931-936 6 p.

    Research output: Contribution to journal › Article › peer-review

    31 Scopus citations

  • Increased Reporting Accuracy of Alzheimer Disease Symptoms in Caribbean Hispanic Informants

    Azar, M., Zhu, C., DeFeis, B., Gu, Y., Ornstein, K., Lawless, S. & Cosentino, S., 2017, In: Alzheimer Disease and Associated Disorders. 31, 4, p. 328-334 7 p.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations

  • Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression

    Calderon, D., Bhaskar, A., Knowles, D. A., Golan, D., Raj, T., Fu, A. Q. & Pritchard, J. K., 2 Nov 2017, In: American Journal of Human Genetics. 101, 5, p. 686-699 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    68 Scopus citations

  • Interactive Effects of Dementia Severity and Comorbidities on Medicare Expenditures

    Zhu, C. W., Cosentino, S., Ornstein, K. A., Gu, Y., Andrews, H. & Stern, Y., 2017, In: Journal of Alzheimer's Disease. 57, 1, p. 305-315 11 p.

    Research output: Contribution to journal › Article › peer-review

    32 Scopus citations

  • Lack of chronic neuroinflammation in the absence of focal hemorrhage in a rat model of low-energy blast-induced TBI

    Gama Sosa, M. A., De Gasperi, R., Perez Garcia, G. S., Sosa, H., Searcy, C., Vargas, D., Janssen, P. L., Perez, G. M., Tschiffely, A. E., Janssen, W. G., McCarron, R. M., Hof, P. R., Haghighi, F. G., Ahlers, S. T. & Elder, G. A., 10 Nov 2017, In: Acta neuropathologica communications. 5, 1, p. 80 1 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations

  • Large-Scale Identification of Common Trait and Disease Variants Affecting Gene Expression

    CommonMind Consortium, 1 Jun 2017, In: American Journal of Human Genetics. 100, 6, p. 885-894 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Scopus citations

  • Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience

    for the Alzheimer's Disease Neuroimaging Initative, 29 Nov 2017, In: Genome Medicine. 9, 1, 100.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    48 Scopus citations

  • Localized cortical chronic traumatic encephalopathy pathology after single, severe axonal injury in human brain

    Shively, S. B., Edgerton, S. L., Iacono, D., Purohit, D. P., Qu, B. X., Haroutunian, V., Davis, K. L., Diaz-Arrastia, R. & Perl, D. P., 1 Mar 2017, In: Acta Neuropathologica. 133, 3, p. 353-366 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    40 Scopus citations

  • Longitudinal Cognitive Profiles in Diabetes: Results From the National Alzheimer's Coordinating Center's Uniform Data

    Sano, M., Zhu, C. W., Grossman, H. & Schimming, C., Oct 2017, In: Journal of the American Geriatrics Society. 65, 10, p. 2198-2204 7 p.

    Research output: Contribution to journal › Article › peer-review

    19 Scopus citations

  • Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

    Huang, M., Yang, W., Feng, Q., Chen, W., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., Shaw, L. M., Kaye, J., Quinn, J., Silbert, L., Lind, B., & 219 othersCarter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., DeToledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Maillard, P., Olichney, J., DeCarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., 12 Jan 2017, In: Scientific Reports. 7, 39880.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein

    Kaur, G., Pawlik, M., Gandy, S. E., Ehrlich, M. E., Smiley, J. F. & Levy, E., 1 Jul 2017, In: Molecular Psychiatry. 22, 7, p. 981-989 9 p.

    Research output: Contribution to journal › Article › peer-review

    29 Scopus citations

  • Medicare Expenditure Correlates of Atrophy and Cerebrovascular Disease in Older Adults

    Last, B. S., García Rubio, M. J., Zhu, C. W., Cosentino, S., Manly, J. J., DeCarli, C., Stern, Y. & Brickman, A. M., 15 Mar 2017, In: Experimental Aging Research. 43, 2, p. 149-160 12 p.

    Research output: Contribution to journal › Article › peer-review

    3 Scopus citations

  • Midlife interventions are critical in prevention, delay, or improvement of Alzheimer's disease and vascular cognitive impairment and dementia

    Gandy, S., Bartfai, T., Lees, G. V. & Sano, M., 2017, In: F1000Research. 6, 413.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Military Blast Injury and Chronic Neurodegeneration: Research Presentations from the 2015 International State-of-The-Science Meeting

    Agoston, D., Arun, P., Bellgowan, P., Broglio, S., Cantu, R., Cook, D., Da Silva, U. O., Dickstein, D., Elder, G., Fudge, E., Gandy, S., Gill, J., Glenn, J. F., Gupta, R. K., Hinds, S., Hoffman, S., Lattimore, T., Lin, A., Lu, K. P., Maroon, J., & 5 othersOkonkwo, D., Perl, D., Robinson, M., Rosen, C. & Smith, D., Sep 2017, In: Journal of Neurotrauma. 34, S1, p. S6-S17

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • Molecular and cellular reorganization of neural circuits in the human lineage

    Sousa, A. M. M., Zhu, Y., Raghanti, M. A., Kitchen, R. R., Onorati, M., Tebbenkamp, A. T. N., Stutz, B., Meyer, K. A., Li, M., Kawasawa, Y. I., Liu, F., Perez, R. G., Mele, M., Carvalho, T., Skarica, M., Gulden, F. O., Pletikos, M., Shibata, A., Stephenson, A. R., Edler, M. K., & 18 othersEly, J. J., Elsworth, J. D., Horvath, T. L., Hof, P. R., Hyde, T. M., Kleinman, J. E., Weinberger, D. R., Reimers, M., Lifton, R. P., Mane, S. M., Noonan, J. P., State, M. W., Lein, E. S., Knowles, J. A., Marques-Bonet, T., Sherwood, C. C., Gerstein, M. B. & Sestan, N., 24 Nov 2017, In: Science. 358, 6366, p. 1027-1032 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    140 Scopus citations

  • Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease

    McKenzie, A. T., Moyon, S., Wang, M., Katsyv, I., Song, W. M., Zhou, X., Dammer, E. B., Duong, D. M., Aaker, J., Zhao, Y., Beckmann, N., Wang, P., Zhu, J., Lah, J. J., Seyfried, N. T., Levey, A. I., Katsel, P., Haroutunian, V., Schadt, E. E., Popko, B., & 2 othersCasaccia, P. & Zhang, B., 6 Nov 2017, In: Molecular Neurodegeneration. 12, 1, 82.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    65 Scopus citations

  • Multisite assessment of aging-related tau astrogliopathy (ARTAG)

    Kovacs, G. G., Xie, S. X., Lee, E. B., Robinson, J. L., Caswell, C., Irwin, D. J., Toledo, J. B., Johnson, V. E., Smith, D. H., Alafuzoff, I., Attems, J., Bencze, J., Bieniek, K. F., Bigio, E. H., Bodi, I., Budka, H., Dickson, D. W., Dugger, B. N., Duyckaerts, C., Ferrer, I., & 42 othersForrest, S. L., Gelpi, E., Gentleman, S. M., Giaccone, G., Grinberg, L. T., Halliday, G. M., Hatanpaa, K. J., Hof, P. R., Hofer, M., Hortobágyi, T., Ironside, J. W., King, A., Kofler, J., Kövari, E., Kril, J. J., Love, S., Mackenzie, I. R., Mao, Q., Matej, R., McLean, C., Munoz, D. G., Murray, M. E., Neltner, J., Nelson, P. T., Ritchie, D., Rodriguez, R. D., Rohan, Z., Rozemuller, A., Sakai, K., Schultz, C., Seilhean, D., Smith, V., Tacik, P., Takahashi, H., Takao, M., Thal, D. R., Weis, S., Wharton, S. B., White, C. L., Woulfe, J. M., Yamada, M. & Trojanowski, J. Q., Jul 2017, In: Journal of Neuropathology and Experimental Neurology. 76, 7, p. 605-619 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    32 Scopus citations

  • No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson’s disease in nine ADHD candidate SNPs

    International Parkinson Disease Genomics Consortium members, 1 Jun 2017, In: ADHD Attention Deficit and Hyperactivity Disorders. 9, 2, p. 121-127 7 p.

    Research output: Contribution to journal › Article › peer-review

    12 Scopus citations

  • Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci

    Fullard, J. F., Giambartolomei, C., Hauberg, M. E., Xu, K., Voloudakis, G., Shao, Z., Bare, C., Dudley, J. T., Mattheisen, M., Robakis, N. K., Haroutunian, V. & Roussos, P., 15 May 2017, In: Human Molecular Genetics. 26, 10, p. 1942-1951 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    53 Scopus citations

  • Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat

    Harony-Nicolas, H., Kay, M., du Hoffmann, J., Klein, M. E., Bozdagi-Gunal, O., Riad, M., Daskalakis, N. P., Sonar, S., Castillo, P. E., Hof, P. R., Shapiro, M. L., Baxter, M. G., Wagner, S. & Buxbaum, J. D., 31 Jan 2017, In: eLife. 6, e18904.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    101 Scopus citations

  • Parkinson’s disease-associated LRRK2 hyperactive kinase mutant disrupts synaptic vesicle trafficking in ventral midbrain neurons

    Pan, P. Y., Wang, J., Wang, Q., Hof, P. & Yue, Z., 22 Nov 2017, In: Journal of Neuroscience. 37, 47, p. 11366-11376 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    81 Scopus citations

  • Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

    Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J., Shaw, L. M., & 293 othersKhachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., 1 Dec 2017, In: Scientific Reports. 7, 1, 14052.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Polygenic risk scores in familial Alzheimer disease

    Tosto, G., Bird, T. D., Tsuang, D., Bennett, D. A., Boeve, B. F., Cruchaga, C., Faber, K., Foroud, T. M., Farlow, M., Goate, A. M., Bertlesen, S., Graff-Radford, N. R., Medrano, M., Lantigua, R., Manly, J., Ottman, R., Rosenberg, R., Schaid, D. J., Schupf, N., Stern, Y., & 2 othersSweet, R. A. & Mayeux, R., 21 Mar 2017, In: Neurology. 88, 12, p. 1180-1186 7 p.

    Research output: Contribution to journal › Article › peer-review

    42 Scopus citations

  • Preclinical modelling of militarily relevant traumatic brain injuries: Challenges and recommendations for future directions

    Cernak, I., Stein, D. G., Elder, G. A., Ahlers, S., Curley, K., DePalma, R. G., Duda, J., Ikonomovic, M., Iverson, G. L., Kobeissy, F., Koliatsos, V. E., Leggieri, M. J., Pacifico, A. M., Smith, D. H., Swanson, R., Thompson, F. J. & Tortella, F. C., 29 Jul 2017, In: Brain Injury. 31, 9, p. 1168-1176 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Qualitative and Quantitative Analysis of Primary Neocortical Areas in Selected Mammals

    Van Kann, E., Cozzi, B., Hof, P. R. & Oelschläger, H. H. A., 1 Nov 2017, In: Brain, Behavior and Evolution. 90, 3, p. 193-210 18 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations

  • Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R., Olaso, R., & 426 othersHoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, W. T., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., 1 Sep 2017, In: Nature Genetics. 49, 9, p. 1373-1384 12 p.

    Research output: Contribution to journal › Article › peer-review

    593 Scopus citations

  • Reducing Readmissions among Heart Failure Patients Discharged to Home Health Care: Effectiveness of Early and Intensive Nursing Services and Early Physician Follow-Up

    Murtaugh, C. M., Deb, P., Zhu, C., Peng, T. R., Barrón, Y., Shah, S., Moore, S. M., Bowles, K. H., Kalman, J., Feldman, PH. & Siu, A. L., Aug 2017, In: Health Services Research. 52, 4, p. 1445-1472 28 p.

    Research output: Contribution to journal › Article › peer-review

    68 Scopus citations

  • Serum high-density lipoprotein is associated with better cognitive function in a cross-sectional study of aging women

    Bates, K. A., Sohrabi, H. R., Rainey-Smith, S. R., Weinborn, M., Bucks, R. S., Rodrigues, M., Beilby, J., Howard, M., Taddei, K., Martins, G., Paton, A., Shah, T., Dhaliwal, S. S., Foster, J. K., Martins, I. J., Lautenschlager, N. T., Mastaglia, F. L., Gandy, S. E. & Martins, R. N., 4 Mar 2017, In: International Journal of Neuroscience. 127, 3, p. 243-252 10 p.

    Research output: Contribution to journal › Article › peer-review

    34 Scopus citations

  • Strong correlation of genome-wide expression after traumatic brain injury in vitro and in vivo implicates a role for SORLA

    Lamprecht, M. R., Elkin, B. S., Kesavabhotla, K., Crary, J. F., Hammers, J. L., Huh, J. W., Raghupathi, R. & Morrison, B., 1 Jan 2017, In: Journal of Neurotrauma. 34, 1, p. 97-108 12 p.

    Research output: Contribution to journal › Article › peer-review

    9 Scopus citations

  • Switching between internally and externally focused attention in obsessive-compulsive disorder: Abnormal visual cortex activation and connectivity

    Stern, E. R., Goodman, W. K., Stern, E. R., Hof, P. R., Goodman, W. K. & Muratore, A. F., 30 Jul 2017, In: Psychiatry Research - Neuroimaging. 265, p. 87-97 11 p.

    Research output: Contribution to journal › Article › peer-review

    27 Scopus citations

  • The Impact of Peer Substance Use and Polygenic Risk on Trajectories of Heavy Episodic Drinking Across Adolescence and Emerging Adulthood

    COGA Investigators, 1 Jan 2017, In: Alcoholism: Clinical and Experimental Research. 41, 1, p. 65-75 11 p.

    Research output: Contribution to journal › Article › peer-review

    25 Scopus citations

  • The Prohormone VGF Regulates β Cell Function via Insulin Secretory Granule Biogenesis

    Stephens, S. B., Edwards, R. J., Sadahiro, M., Lin, W. J., Jiang, C., Salton, S. R. & Newgard, C. B., 5 Sep 2017, In: Cell Reports. 20, 10, p. 2480-2489 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    37 Scopus citations

  • The Rare-Variant Generalized Disequilibrium Test for Association Analysis of Nuclear and Extended Pedigrees with Application to Alzheimer Disease WGS Data

    He, Z., Zhang, D., Renton, A. E., Li, B., Zhao, L., Wang, G. T., Goate, A. M., Mayeux, R. & Leal, S. M., 2 Feb 2017, In: American Journal of Human Genetics. 100, 2, p. 193-204 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations

  • The Utility of the Cognitive Function Instrument (CFI) to Detect Cognitive Decline in Non-Demented Older Adults

    Li, C., Neugroschl, J., Luo, X., Zhu, C., Aisen, P., Ferris, S. & Sano, M., 2017, In: Journal of Alzheimer's Disease. 60, 2, p. 427-437 11 p.

    Research output: Contribution to journal › Article › peer-review

    35 Scopus citations

  • Transethnic genome-wide scan identifies novel Alzheimer's disease loci

    Alzheimer's Disease Genetics Consortium, 1 Jul 2017, In: Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    115 Scopus citations

  • Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans

    Alzheimer's Disease Genetics Consortium, 1 Feb 2017, In: Alzheimer's and Dementia. 13, 2, p. 119-129 11 p.

    Research output: Contribution to journal › Article › peer-review

    58 Scopus citations

  • Variation in SWI/SNF Chromatin Remodeling Complex Proteins is Associated with Alcohol Dependence and Antisocial Behavior in Human Populations

    COGA Investigators, Dec 2017, In: Alcoholism: Clinical and Experimental Research. 41, 12, p. 2033-2040 8 p.

    Research output: Contribution to journal › Article › peer-review

    10 Scopus citations
  • 2016

    ABCA7 p.G215S as potential protective factor for Alzheimer's disease

    Sassi, C., Nalls, M. A., Ridge, P. G., Gibbs, J. R., Ding, J., Lupton, M. K., Troakes, C., Lunnon, K., Al-Sarraj, S., Brown, K. S., Medway, C., Clement, N., Lord, J., Turton, J., Bras, J., Almeida, M. R., Passmore, P., Craig, D., Johnston, J., McGuinness, B., & 29 othersTodd, S., Heun, R., Kölsch, H., Kehoe, P. G., Vardy, E. R. L. C., Hooper, N. M., Mann, D. M., Pickering-Brown, S., Brown, K., Lowe, J., Morgan, K., Smith, A. D., Wilcock, G., Warden, D., Holmes, C., Holstege, H., Louwersheimer, E., van der Flier, W. M., Scheltens, P., Van Swieten, J. C., Santana, I., Oliveira, C., Powell, J. F., Kauwe, J. S., Cruchaga, C., Goate, A. M., Singleton, A. B., Guerreiro, R. & Hardy, J., 1 Oct 2016, In: Neurobiology of Aging. 46, p. 235.e1-235.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    38 Scopus citations

  • Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

    Kovacs, G. G., Ferrer, I., Grinberg, L. T., Alafuzoff, I., Attems, J., Budka, H., Cairns, N. J., Crary, J. F., Duyckaerts, C., Ghetti, B., Halliday, G. M., Ironside, J. W., Love, S., Mackenzie, I. R., Munoz, D. G., Murray, M. E., Nelson, P. T., Takahashi, H., Trojanowski, J. Q., Ansorge, O., & 52 othersArzberger, T., Baborie, A., Beach, T. G., Bieniek, K. F., Bigio, E. H., Bodi, I., Dugger, B. N., Feany, M., Gelpi, E., Gentleman, S. M., Giaccone, G., Hatanpaa, K. J., Heale, R., Hof, P. R., Hofer, M., Hortobágyi, T., Jellinger, K., Jicha, G. A., Ince, P., Kofler, J., Kövari, E., Kril, J. J., Mann, D. M., Matej, R., McKee, A. C., McLean, C., Milenkovic, I., Montine, T. J., Murayama, S., Lee, E. B., Rahimi, J., Rodriguez, R. D., Rozemüller, A., Schneider, J. A., Schultz, C., Seeley, W., Seilhean, D., Smith, C., Tagliavini, F., Takao, M., Thal, D. R., Toledo, J. B., Tolnay, M., Troncoso, J. C., Vinters, H. V., Weis, S., Wharton, S. B., White, C. L., Wisniewski, T., Woulfe, J. M., Yamada, M. & Dickson, D. W., 1 Jan 2016, In: Acta Neuropathologica. 131, 1, p. 87-102 16 p.

    Research output: Contribution to journal › Article › peer-review

    335 Scopus citations

  • Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia

    Moreno, J. L., Miranda-Azpiazu, P., García-Bea, A., Younkin, J., Cui, M., Kozlenkov, A., Ben-Ezra, A., Voloudakis, G., Fakira, A. K., Baki, L., Ge, Y., Georgakopoulos, A., Morón, J. A., Milligan, G., López-Giménez, J. F., Robakis, N. K., Logothetis, D. E., Meana, J. J. & González-Maeso, J., 12 Jan 2016, In: Science Signaling. 9, 410

    Research output: Contribution to journal › Article › peer-review

    Open Access
    84 Scopus citations

  • Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

    Alzheimer's Disease Genetics Consortium (ADGC), Feb 2016, In: PLoS ONE. 11, 2, e0148717.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    72 Scopus citations