Alzheimer's Disease Research Center

Icahn School of Medicine at Mount Sinai

181627 Citations
194 h-index
1895 Article
190 Review article
81 Comment/debate
48 Chapter
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Alzheimer's disease-associated CD83(+) microglia are linked with increased immunoglobulin G4 and human cytomegalovirus in the gut, vagal nerve, and brain
Readhead, B. P., Mastroeni, D. F., Wang, Q., Sierra, M. A., de Ávila, C., Jimoh, T. O., Haure-Mirande, J. V., Atanasoff, K. E., Nolz, J., Suazo, C., Barton, N. J., Orszulak, A. R., Chigas, S. M., Tran, K., Mirza, A., Ryon, K., Proszynski, J., Najjar, D., Dudley, J. T. & Liu, S. T. H. & 21 others, Gandy, S., Ehrlich, M. E., Alsop, E., Antone, J., Reiman, R., Funk, C., Best, R. L., Jhatro, M., Kamath, K., Shon, J., Kowalik, T. F., Bennett, D. A., Liang, W. S., Serrano, G. E., Beach, T. G., Van Keuren-Jensen, K., Mason, C. E., Chan, Y., Lim, E. T., Tortorella, D. & Reiman, E. M., Jan 2025, In: Alzheimer's and Dementia. 21, 1, e14401.
Research output: Contribution to journal › Article › peer-review

Open Access
APOE genotype and brain amyloid are associated with changes in the plasma proteome in elderly subjects without dementia
Philippi, S. M., Kailash, B. P., Raj, T. & Castellano, J. M., Feb 2025, In: Annals of Clinical and Translational Neurology. 12, 2, p. 366-382 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
A structural haplotype in the 17q21.31 MAPT region is associated with increased risk for chronic traumatic encephalopathy endophenotypes
the DIAGNOSE CTE Research Project Investigators, 2025, (Accepted/In press) In: Cell Reports Medicine. 102084.
Research output: Contribution to journal › Article › peer-review

Open Access
Behavioral variant frontotemporal dementia with pathogenic variant in MAPT presenting as dementia with Lewy body disease
Xia, T., Li, C., Iverson, A., Spat-Lemus, J., Woroch, A. & Naasan, G., 2025, In: Neurocase. 31, 1, p. 23-28 6 p.
Research output: Contribution to journal › Article › peer-review
Biochemical characterization of Tau protein changes and amyloid dynamics in a novel non-transgenic rat model of tauopathy
Langer Horvat, L., Španić Popovački, E., Babić Leko, M., Zubčić, K., Mustapić, M., Hof, P. R. & Šimić, G., 2025, (Accepted/In press) In: Journal of Neural Transmission.
Research output: Contribution to journal › Article › peer-review
Brain Signatures of Very Early Cognitive Decline in Asymptomatic Middle-Aged Offspring of People With Alzheimer's Disease
Ramsingh, N., Lin, H. M., Ouyang, Y., Ravona-Springer, R., Livny, A., Soleimani, L., Bendlin, B. B., Matatov, A., Niv, T., Shamir, T., Ganmore, I., Heymann, A., Sano, M., Azuri, J. & Beeri, M. S., 1 Mar 2025, In: International Journal of Geriatric Psychiatry. 40, 3, p. e70060
Research output: Contribution to journal › Article › peer-review
CASP8 intronic expansion identified by poly-glycine-arginine pathology increases Alzheimer’s disease risk
Nguyen, L., Ajredini, R., Guo, S., Romano, L. E. L., Tomas, R. F., Bell, L. R., Ranum, P. T., Zu, T., Coronel, M. B., Kelley, C. P., Redding-Ochoa, J., Nizamis, E., Melloni, A., Connors, T. R., Gaona, A., Thangaraju, K., Pletnikova, O., Brent Clark, H., Davidson, B. L. & Yachnis, A. T. & 10 others, Golde, T. E., Lou, X. Y., Wang, E. T., Renton, A. E., Goate, A., Valdmanis, P. N., Prokop, S., Troncoso, J. C., Hyman, B. T. & Ranum, L. P. W., 19 Feb 2025, In: Proceedings of the National Academy of Sciences of the United States of America. 122, 7, e2416885122.
Research output: Contribution to journal › Article › peer-review

Open Access
Characterizing white matter and vascular pathologies in brain donors exposed to repetitive head impacts
Emrani, S., Koutures, A., Tripodis, Y., Uretsky, M., Abdolmohammadi, B., Nowinski, C., Daneshvar, D. H., Dwyer, B., Katz, D. I., Goldstein, L. E., Cantu, R. C., Martin, B. M., Palmisano, J. N., Dams-O’Connor, K., Crary, J. F., Stern, R. A., Mez, J., Alvarez, V. E., Huber, B. R. & McKee, A. C. & 2 others, Stein, T. D. & Alosco, M. L., Jun 2025, In: Acta Neuropathologica. 149, 1, 24.
Research output: Contribution to journal › Article › peer-review

Open Access
Clinical, Genomic, and Neurophysiological Correlates of Lifetime Suicide Attempts among Individuals with an Alcohol Use Disorder
Barr, P. B., Neale, Z., Chatzinakos, C., Schulman, J., Mullins, N., Zhang, J., Chorlian, D. B., Kamarajan, C., Kinreich, S., Pandey, A. K., Pandey, G., Saenz De Viteri, S., Acion, L., Bauer, L., Bucholz, K. K., Chan, G., Dick, D. M., Edenberg, H. J., Foroud, T. & Goate, A. & 10 others, Hesselbrock, V., Johnson, E. C., Kramer, J. R., Lai, D., Plawecki, M. H., Salvatore, J., Wetherill, L., Agrawal, A., Porjesz, B. & Meyers, J. L., 2025, (Accepted/In press) In: Complex Psychiatry.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Cohen-mansfield agitation inventory total score as a measure of agitation and aggression in Alzheimer's disease: A factor analysis
Hendrix, S. B., Sano, M., Lyketsos, C., Rosenberg, P. B., Porsteinsson, A. P., Brown, B. L., Hedges, D. & Cummings, J. L., 2025, (Accepted/In press) In: International Psychogeriatrics. 100056.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Copy Number Variation and Haplotype Analysis of 17q21.31 Reveals Increased Risk Associated with Progressive Supranuclear Palsy and Gene Expression Changes in Neuronal Cells
PSP Genetics Study Group, 2025, (Accepted/In press) In: Movement Disorders.
Research output: Contribution to journal › Article › peer-review

Open Access
Correction to: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction (Nature Neuroscience, (2021), 24, 10, (1367-1376), 10.1038/s41593-021-00908-3)
COGA Collaborators, Jan 2025, In: Nature Neuroscience. 28, 1, p. 213 1 p.
Research output: Contribution to journal › Comment/debate

Open Access

New Genetic Risk Study Findings Have Been Reported by Investigators at Icahn School of Medicine at Mount Sinai (Long-read Rna Sequencing Atlas of Human Microglia Isoforms Elucidates Disease-associated Genetic Regulation of Splicing)
Zeng, B., Sebra, R., Raj, T., Haroutunian, V., Roussos, P., Fullard, J., De Witte, L. & Hoffman, G.
9/04/25
1 item of Media coverage
Press/Media
Research on Lewy Body Disease Detailed by a Researcher at University College London (UCL) (Investigation of the genetic aetiology of Lewy body diseases with and without dementia)
Goate, A.
1/04/25
1 item of Media coverage
Press/Media
New AI tool dives deeper into sleep
Nadkarni, G., Suarez-Farinas, M., Kovatch, P. & Parekh, A.
1/04/25
1 item of Media coverage
Press/Media
Researchers at University of Florida Have Reported New Data on Alzheimer Disease ( casp8 Intronic Expansion Identified By Poly-glycine-arginine Pathology Increases Alzheimer's Disease Risk)
Goate, A. & Renton, A. E.
1/04/25
1 item of Media coverage
Press/Media
University of Zagreb School of Medicine Reports Findings in Alzheimer Disease (Biochemical characterization of Tau protein changes and amyloid dynamics in a novel non-transgenic rat model of tauopathy)
Hof, P.
31/03/25
1 item of Media coverage
Press/Media
New Findings on Alzheimer Disease from Icahn School of Medicine at Mount Sinai Summarized (Brain Signatures of Very Early Cognitive Decline In Asymptomatic Middle-aged Offspring of People With Alzheimer's Disease)
Sano, M. & Soleimani, L.
27/03/25
1 item of Media coverage
Press/Media
Scientists Announce Possible Breakthrough in Delaying Alzheimer’s
Gandy, S.
21/03/25
1 item of Media coverage
Press/Media
New AI Model Analyzes Full Night of Sleep With High Accuracy in Largest Study of Its Kind
Nadkarni, G., Suarez-Farinas, M., Kovatch, P. & Parekh, A.
17/03/25
2 items of Media coverage
Press/Media
New AI tool revolutionizes sleep analysis with comprehensive sleep data
Nadkarni, G., Suarez-Farinas, M., Kovatch, P. & Parekh, A.
17/03/25
2 items of Media coverage
Press/Media
AI Model Analyzes Sleep with High Accuracy in Major Study
Nadkarni, G., Suarez-Farinas, M., Kovatch, P. & Parekh, A.
17/03/25
1 item of Media coverage
Press/Media
Icahn School of Medicine at Mount Sinai Researchers Provide New Data on Central Nervous System (The thalamus: Structure, function, and neurotherapeutics)
Panov , F., Hof, P., Ghatan,, S., Jimenez-Shahed, J., Mayberg,, H., Figee, M. & Balchandani, P.
14/03/25
1 item of Media coverage
Press/Media
Researchers from State University of New York (SUNY) Stony Brook Describe Findings in Amyloidosis (Exposure Duration and Cerebral Amyloidosis In the Olfactory Cortex of World Trade Center Responders: a Positron Emission Tomography and Magnetic ...)
Gandy, S.
4/03/25
1 item of Media coverage
Press/Media