Alzheimer's Disease Research Center

Icahn School of Medicine at Mount Sinai

50 Active
190 Finished

The role of metabotropic mGluR2 receptors in the chronic cognitive and behavioral effects of blast exposure
Elder, G.
U.S. Department of Veterans Affairs
1/10/22 → 30/09/23
Project: Research
Profiling and Elucidating Molecular Mechanism of Neurodegeneration in Parki
Yue, Z. Z., Yang, N. N., Crary, J., Wu, Z. Z., Blanchard, J. J. & Zhang, B. B.
Parkinson's Foundation
30/06/22 → 30/06/26
Project: Research
2022 Neurobiology of Brain Disorders GRC and GRS
Goate, A.
National Institute on Aging
1/04/22 → 31/03/23
Project: Research
Neuroprotective signaling and transcriptional pathways in microglia associated with Alzheimer's disease
Goate, A., Tarakhovsky, A. A. & Schaefer, A.
National Institute on Aging
1/02/22 → 30/11/23
Project: Research
Biomarkers of COVID-19 Induced Cognitive Loss in Diverse Older Populations
Li, C.
Alzheimer's Association
1/01/22 → …
Project: Research
SYSTEMS INTEGRATION AND THERAPEUTICS TRANSLATION IN ALZHEIMER'S DISEASE
Goate, A. & Marcora, E.
Cure Alzheimer's Fund
1/01/22 → …
Project: Research
MICROGLIAL-SPECIFIC INPP5D KNOCKDOWN MODULATES BEHAVIOR, AMYLOIDOSIS AND TAUOPATHY IN ALZHEIMER'S MOUSE MODELS
Gandy, S. & Ehrlich, M.
Cure Alzheimer's Fund
1/01/22 → …
Project: Research
SYSTEMS INTEGRATION AND THERAPEUTICS TRANSLATION IN ALZHEIMER'S DISEASE
Goate, A. & Marcora, E.
Cure Alzheimer's Fund
1/01/22 → …
Project: Research
Elevated FSH - A Driver for Sex Differences in Alzheimer's Disease
Zaidi, M., Yuen, T. & Haroutunian, V.
National Institute on Aging
30/09/21 → 31/08/23
Project: Research
A regulome and transcriptome atlas of fetal and adult human neurogenesis
Roussos, P., Cai, L., Hof, P., Sestan, N. & Yuan, G.
NATIONAL INSTITUTE OF MENTAL HEALTH
20/09/21 → 19/09/24
Project: Research
Genomics Core
Raj, T. & Raj, T. T.
National Institute of Neurological Disorders and Stroke
15/08/21 → 31/08/23
Project: Research
Project 1: Determination of molecular differences caused by tauopathy-associated H1 and H2 haplotypes
Goate, A. & Goate, A. A. M.
National Institute of Neurological Disorders and Stroke
1/07/21 → 31/08/23
Project: Research

139926 Citations
173 h-index
1640 Article
159 Review article
67 Comment/debate
46 Chapter
More

Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons
Popova, D., Gameiro-Ros, I., Youssef, M. M., Zalamea, P., Morris, A. D., Prytkova, I., Jadali, A., Kwan, K. Y., Kamarajan, C., Salvatore, J. E., Xuei, X., Chorlian, D. B., Porjesz, B., Kuperman, S., Dick, D. M., Goate, A., Edenberg, H. J., Tischfield, J. A., Pang, Z. P., Slesinger, P. A., & 1 othersHart, R. P., Feb 2023, In: Molecular Psychiatry. 28, 2, p. 746-758 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
A single closed head injury in male adult mice induces chronic, progressive white matter atrophy and increased phospho-tau expressing oligodendrocytes
Havlicek, D. F., Furhang, R., Nikulina, E., Smith-Salzberg, B., Lawless, S., Severin, S. A., Mallaboeva, S., Nayab, F., Seifert, A. C., Crary, J. F. & Bergold, P. J., Jan 2023, In: Experimental Neurology. 359, 114241.
Research output: Contribution to journal › Article › peer-review
BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPT^P301S mouse model of tauopathy
Perez-Garcia, G., Bicak, M., Haure-Mirande, J. V., Perez, G. M., Otero-Pagan, A., Gama Sosa, M. A., De Gasperi, R., Sano, M., Barlow, C., Gage, F. H., Readhead, B., Ehrlich, M. E., Gandy, S. & Elder, G. A., 16 Feb 2023, In: Neuroscience Letters. 797, 137080.
Research output: Contribution to journal › Article › peer-review
Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts
McKee, A. C., Stein, T. D., Huber, B. R., Crary, J. F., Bieniek, K., Dickson, D., Alvarez, V. E., Cherry, J. D., Farrell, K., Butler, M., Uretsky, M., Abdolmohammadi, B., Alosco, M. L., Tripodis, Y., Mez, J. & Daneshvar, D. H., 2023, (Accepted/In press) In: Acta Neuropathologica.
Research output: Contribution to journal › Review article › peer-review

Open Access
Correction: The molecular identity of the TLQP-21 peptide receptor (Cellular and Molecular Life Sciences, (2021), 78, 23, (7133-7144), 10.1007/s00018-021-03944-1)
Sahu, B. S., Nguyen, M. E., Rodriguez, P., Pallais, J. P., Ghosh, V., Razzoli, M., Sham, Y. Y., Salton, S. R. & Bartolomucci, A., Mar 2023, In: Cellular and Molecular Life Sciences. 80, 3, 66.
Research output: Contribution to journal › Comment/debate

Open Access
Evaluating memory testing to distinguish dementia severity among White, Black, and Spanish-speaking individuals in the Uniform Data Set (UDS)
Loizos, M., Zhu, C. W., Akrivos, J., Sewell, M., Li, C., Neugroschl, J., Melnick, J., Ljekocevic, M., Martin, J., Grossman, H., Aloysi, A., Schimming, C. & Sano, M., 2023, (Accepted/In press) In: Alzheimer's and Dementia.
Research output: Contribution to journal › Article › peer-review

Open Access
Genetic nurture effects for alcohol use disorder
COGA Collaborators, Feb 2023, In: Molecular Psychiatry. 28, 2, p. 759-766 8 p.
Research output: Contribution to journal › Article › peer-review
Integrative transcriptomic analysis of the amyotrophic lateral sclerosis spinal cord implicates glial activation and suggests new risk genes
NYGC ALS Consortium, Jan 2023, In: Nature Neuroscience. 26, 1, p. 150-162 13 p.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease
for the Dominantly Inherited Alzheimer Network, Feb 2023, In: Alzheimer's and Dementia. 19, 2, p. 632-645 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Progressive Transcriptional Changes in the Amygdala Implicate Neuroinflammation in the Effects of Repetitive Low-Level Blast Exposure in Male Rats
Gasperi, R. D., Gama Sosa, M. A., Perez Garcia, G. S., Perez, G. M., Abutarboush, R., Kawoos, U., Statz, J. K., Patterson, J., Hof, P. R., Katsel, P., Cook, D. G., Ahlers, S. T. & Elder, G. A., 1 Mar 2023, In: Journal of Neurotrauma. 40, 5-6, p. 561-577 17 p.
Research output: Contribution to journal › Article › peer-review
Repetitive head impacts and chronic traumatic encephalopathy are associated with TDP-43 inclusions and hippocampal sclerosis
Nicks, R., Clement, N. F., Alvarez, V. E., Tripodis, Y., Baucom, Z. H., Huber, B. R., Mez, J., Alosco, M. L., Aytan, N., Cherry, J. D., Cormier, K. A., Kubilius, C., Mathias, R., Svirsky, S. E., Pothast, M. J., Hildebrandt, A. M., Chung, J., Han, X., Crary, J. F., McKee, A. C., & 2 othersFrosch, M. P. & Stein, T. D., 2023, (Accepted/In press) In: Acta Neuropathologica.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Returning integrated genomic risk and clinical recommendations: The eMERGE study
eMERGE Consortium, Apr 2023, In: Genetics in Medicine. 25, 4, 100006.
Research output: Contribution to journal › Article › peer-review

Open Access

Icahn School of Medicine at Mount Sinai Reports Findings in Depression (Stress-related reduction of hippocampal subfield volumes in major depressive disorder: A 7-Tesla study)
Gaurav Verma, Hung-Mo Lin, Yael Jacob, Stephanie Brown, Lazar Fleysher, James Murrough, Patrick Hof & Priti Balchandani
7/03/23
1 item of Media coverage
Press/Media
Reports from New York University (NYU) Add New Data to Findings in Gene Therapy (The Contribution of Amyloid Deposition In the Aortic Valve To Calcification and Aortic Stenosis)
Samuel Gandy
21/02/23
1 item of Media coverage
Press/Media
AltPep Strengthens Advisory Board with Three Leading Experts in Alzheimer’s Disease and Neurodegenerative Disorders
Samuel Gandy
9/02/23
9 items of Media coverage
Press/Media
Study Data from Research and Development Service Provide New Insights into Post-Traumatic Stress Disorders (Progressive Transcriptional Changes In the Amygdala Implicate Neuroinflammation In the Effects of Repetitive Low-level Blast Exposure In ...)
Patrick Hof & Gregory Elder
1/02/23
1 item of Media coverage
Press/Media
Study Results from Washington University Update Understanding of Alzheimer Disease (Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer's disease)
Yan Li & Alison Goate
31/01/23
1 item of Media coverage
Press/Media
Katie Taylor vs. Amanda Serrano fight reignites debate around 2-minute rounds in women's boxing
Patrick Hof
31/01/23
3 items of Media coverage
Press/Media
New Alzheimer's drug appears to slow progression of disease
Mary Sano
30/01/23
1 item of Media coverage
Press/Media
Initial Symptoms Could Predict How Fast Alzheimer's Progresses
Mary Sano & David Reich
25/01/23 → 27/01/23
104 items of Media coverage
Press/Media
Initial Symptoms Could Predict How Fast Alzheimer's Progresses.
Mary Sano
25/01/23
1 item of Media coverage
Press/Media
New Amyotrophic Lateral Sclerosis Study Findings Have Been Reported from Icahn School of Medicine at Mount Sinai (Integrative Transcriptomic Analysis of the Amyotrophic Lateral Sclerosis Spinal Cord Implicates Glial Activation and Suggests New ...)
Sanan Venkatesh & Towfique Raj
23/01/23
1 item of Media coverage
Press/Media
University of Zagreb School of Medicine Researchers Add New Study Findings to Research in Alzheimer Disease (Heavy Metals and Essential Metals Are Associated with Cerebrospinal Fluid Biomarkers of Alzheimer's Disease)
Patrick Hof
23/01/23
1 item of Media coverage
Press/Media
New Findings Reported from Icahn School of Medicine at Mount Sinai Describe Advances in Alzheimer Disease [Dual-specificity Protein Phosphatase 4 (Dusp4) Overexpression Improves Learning Behavior Selectively In Female 5xfad Mice, and Reduces ...]
Noam Beckmann, Qian Wang, Eric Schadt, Minghui Wang, Michelle Ehrlich, Samuel Gandy & Rajeev Joshi
16/01/23
1 item of Media coverage
Press/Media