Addiction Institute of Mount Sinai

2023

Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons

Popova, D., Gameiro-Ros, I., Youssef, M. M., Zalamea, P., Morris, A. D., Prytkova, I., Jadali, A., Kwan, K. Y., Kamarajan, C., Salvatore, J. E., Xuei, X., Chorlian, D. B., Porjesz, B., Kuperman, S., Dick, D. M., Goate, A., Edenberg, H. J., Tischfield, J. A., Pang, Z. P., Slesinger, P. A., & 1 othersHart, R. P., Feb 2023, In: Molecular Psychiatry. 28, 2, p. 746-758 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Altered prefrontal signaling during inhibitory control in a salient drug context in cocaine use disorder

Ceceli, A. O., Parvaz, M. A., King, S., Schafer, M., Malaker, P., Sharma, A., Alia-Klein, N. & Goldstein, R. Z., 5 Jan 2023, In: Cerebral Cortex. 33, 3, p. 597-611 15 p.

Research output: Contribution to journal › Article › peer-review

A Regional and Projection-Specific Role of RGSz1 in the Ventrolateral Periaqueductal Grey in the Modulation of Morphine Reward

Sakloth, F., Sanchez-Reyes, O. B., Ruiz, A., Nicolais, A., Serafini, R. A., Pryce, K. D., Bertherat, F., Torres-Berrío, A., Gomes, I., Devi, L. A., Wacker, D. & Zachariou, V., 1 Jan 2023, In: Molecular Pharmacology. 103, 1, p. 1-8 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Associations Between Long-Term and Near-Term Stressful Life Events, Suicide Crisis Syndrome, and Suicidal Ideation

Rogers, M. L., Richards, J. A., Cao, E., Krumerman, M., Barzilay, S., Blum, Y., Chistopolskaya, K., Çinka, E., Dudeck, M., Husain, M. I., Yilmaz, F. K., Kravtsova, N. A., Kuśmirek, O., Menon, V., Peper-Nascimento, J., Pilecka, B., Titze, L., Valvassori, S. S., You, S. & Galynker, I., 2023, (Accepted/In press) In: International Journal of Stress Management.

Research output: Contribution to journal › Article › peer-review

Cannabis use is associated with low plasma endocannabinoid Anandamide in individuals with psychosis

Bassir Nia, A., Gibson, C. L., Spriggs, S. A., Jankowski, S. E., DeFrancisco, D., Swift, A., Perkel, C., Galynker, I., Honrao, C., Makriyannis, A. & Hurd, Y. L., 2023, (Accepted/In press) In: Journal of Psychopharmacology.

Research output: Contribution to journal › Article › peer-review

Cocaethylene cardiotoxicity in emergency department patients with acute drug overdose

Shastry, S., Manoochehri, O., Richardson, L. D. & Manini, A. F., Feb 2023, In: Academic Emergency Medicine. 30, 2, p. 82-88 7 p.

Research output: Contribution to journal › Article › peer-review

Computational models of behavioral addictions: State of the art and future directions

Kato, A., Shimomura, K., Ognibene, D., Parvaz, M. A., Berner, L. A., Morita, K. & Fiore, V. G., May 2023, In: Addictive Behaviors. 140, 107595.

Research output: Contribution to journal › Article › peer-review

CpH methylome analysis in human cortical neurons identifies novel gene pathways and drug targets for opioid use disorder

Traumatic Stress Brain Research Group, 19 Jan 2023, In: Frontiers in Psychiatry. 13, 1078894.

Research output: Contribution to journal › Article › peer-review

Open Access

Cross-national presence and sociodemographic correlates of the suicide crisis syndrome

Rogers, M. L., McMullen, L., Liang, Y., Perez, N., Richards, J. A., Akülker, G., Barzilay, S., Bilici, R., Blum, Y., Chistopolskaya, K., Dudeck, M., Husain, M. I., Kuśmirek, O., Luiz, J. M., Menon, V., Pilecka, B., Sadovnichaya, V., Titze, L., Valvassori, S. S., You, S., & 1 othersGalynker, I., 15 May 2023, In: Journal of Affective Disorders. 329, p. 1-8 8 p.

Research output: Contribution to journal › Article › peer-review

Effects of Early-Life Adversities on Neuropsychiatric and Executive Functions in HIV-Positive Adults

Clark, U. S., Herrington, O. D. & Hegde, R. R., 2 Jan 2023, In: Journal of the International Neuropsychological Society. 29, 1, p. 68-79 12 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Factor Structure and Validation of the Revised Suicide Crisis Inventory in a Korean Population

Park, J. Y., Rogers, M. L., Bloch-Elkouby, S., Richards, J. A., Lee, S., Galynker, I. & You, S., Feb 2023, In: Psychiatry Investigation. 20, 2, p. 162-173 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Functional characterization of a novel PIP₂-independent GIRK2 channel gating mechanism

Nguyen, H., Glaaser, I. W., Mathiharan, Y. K., Zhao, Y. & Slesinger, P. A., 10 Feb 2023, In: Biophysical Journal. 122, 3S1, p. 373a

Research output: Contribution to journal › Article › peer-review

Genetic nurture effects for alcohol use disorder

COGA Collaborators, Feb 2023, In: Molecular Psychiatry. 28, 2, p. 759-766 8 p.

Research output: Contribution to journal › Article › peer-review

Histone H3 dopaminylation in nucleus accumbens, but not medial prefrontal cortex, contributes to cocaine-seeking following prolonged abstinence

Stewart, A. F., Lepack, A. L., Fulton, S. L., Safovich, P. & Maze, I., Jun 2023, In: Molecular and Cellular Neurosciences. 125, 103824.

Research output: Contribution to journal › Article › peer-review

Open Access

Long-Term Outcomes of Adolescent THC Exposure on Translational Cognitive Measures in Adulthood in an Animal Model and Computational Assessment of Human Data

Ferland, J. M. N., Ellis, R. J., Betts, G., Silveira, M. M., De Firmino, J. B., Winstanley, C. A. & Hurd, Y. L., 4 Jan 2023, In: JAMA Psychiatry. 80, 1, p. 66-76 11 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Optical control of neuronal activities with photoswitchable nanovesicles

Xiong, H., Alberto, K. A., Youn, J., Taura, J., Morstein, J., Li, X., Wang, Y., Trauner, D., Slesinger, P. A., Nielsen, S. O. & Qin, Z., Jan 2023, In: Nano Research. 16, 1, p. 1033-1041 9 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Pattern and implications of neurological examination findings in autosomal dominant Alzheimer disease

for the Dominantly Inherited Alzheimer Network, Feb 2023, In: Alzheimer's and Dementia. 19, 2, p. 632-645 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Social trauma engages lateral septum circuitry to occlude social reward

Li, L., Durand-de Cuttoli, R., Aubry, A. V., Burnett, C. J., Cathomas, F., Parise, L. F., Chan, K. L., Morel, C., Yuan, C., Shimo, Y., Lin, H. Y., Wang, J. & Russo, S. J., 26 Jan 2023, In: Nature. 613, 7945, p. 696-703 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Spinal Cord Sensitization and Spinal Inflammation from an In Vivo Rat Endplate Injury Associated with Painful Intervertebral Disc Degeneration

Lai, A., Iliff, D., Zaheer, K., Wang, D., Gansau, J., Laudier, D. M., Zachariou, V. & Iatridis, J. C., Feb 2023, In: International Journal of Molecular Sciences. 24, 4, 3425.

Research output: Contribution to journal › Article › peer-review

Open Access

Study protocol for a multisite randomized controlled trial of a peer navigator intervention for emergency department patients with nonfatal opioid overdose

Doran, K. M., Welch, A. E., Jeffers, A., Kepler, K. L., Chambless, D., Cowan, E., Wittman, I., Regina, A., Chang, T. E., Parraga, S., Tapia, J., Diaz, C., Gwadz, M., Cleland, C. M. & McNeely, J., Mar 2023, In: Contemporary Clinical Trials. 126, 107111.

Research output: Contribution to journal › Article › peer-review

Syringe Service Program Perspectives on Barriers, Readiness, and Programmatic Needs to Support Rollout of the COVID-19 Vaccine

Corcorran, M. A., Austin, E. J., Behrends, C. N., Briggs, E. S., Frost, M. C., Juarez, A. M., Frank, N. D., Healy, E., Prohaska, S. M., Lakosky, P. A., Kapadia, S. N., Perlman, D. C., Schackman, B. R., Des Jarlais, D. C., Williams, E. C. & Glick, S. N., 1 Jan 2023, In: Journal of Addiction Medicine. 17, 1, p. E36-E41

Research output: Contribution to journal › Article › peer-review

Who are the patients who deny suicidal intent? Exploring patients' characteristics associated with self-disclosure and denial of suicidal intent

Bloch-Elkouby, S., Zilcha-Mano, S., Rogers, M. L., Park, J. Y., Manlongat, K., Krumerman, M. & Galynker, I., Feb 2023, In: Acta Psychiatrica Scandinavica. 147, 2, p. 205-216 12 p.

Research output: Contribution to journal › Article › peer-review

Whole-brain white matter abnormalities in human cocaine and heroin use disorders: association with craving, recency, and cumulative use

Gaudreault, P. O., King, S. G., Malaker, P., Alia-Klein, N. & Goldstein, R. Z., Feb 2023, In: Molecular Psychiatry. 28, 2, p. 780-791 12 p.

Research output: Contribution to journal › Article › peer-review

2022

17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes

International Parkinson’s Disease Genomics Consortium (IPDGC), Dec 2022, In: Molecular Neurodegeneration. 17, 1, 48.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

A case report and first-person account of an individual at risk for psychosis who improved during the COVID-19 pandemic

Herrera, S. N., Sarac, C., Bilgrami, Z. R., Dobbs, M. F., Jespersen, R., Haas, S. S., Garg, S., Shaik, R. B., Landa, Y. & Corcoran, C. M., 2022, In: Psychosis. 14, 2, p. 190-199 10 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Adjunctive Management of Opioid Withdrawal with the Nonopioid Medication Cannabidiol

Kudrich, C., Hurd, Y. L., Salsitz, E. & Wang, A. L., 1 Oct 2022, In: Cannabis and Cannabinoid Research. 7, 5, p. 569-581 13 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

A medical student-led model for telephone-based opioid overdose education and naloxone distribution during the COVID-19 pandemic

Hughes, T. M., Kalicki, A., Huxley-Reicher, Z., Toribio, W., Samuels, D. L., Weiss, J. J., Herscher, M. & Wang, L., 2022, In: Substance Abuse. 43, 1, p. 988-992 5 p.

Research output: Contribution to journal › Article › peer-review

A Meta-Analysis of fMRI Studies of Youth Cannabis Use: Alterations in Executive Control, Social Cognition/Emotion Processing, and Reward Processing in Cannabis Using Youth

Hammond, C. J., Allick, A., Park, G., Rizwan, B., Kim, K., Lebo, R., Nanavati, J., Parvaz, M. A. & Ivanov, I., Oct 2022, In: Brain Sciences. 12, 10, 1281.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

An integrative study of the microbiome gut-brain-axis and hippocampal inflammation in psychosis: Persistent effects from mode of birth

Joe, P., Clemente, J. C., Piras, E., Wallach, D. S., Robinson-Papp, J., Boka, E., Remsen, B., Bonner, M., Kimhy, D., Goetz, D., Hoffman, K., Lee, J., Ruby, E., Fendrich, S., Gonen, O. & Malaspina, D., Sep 2022, In: Schizophrenia Research. 247, p. 101-115 15 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

An Interpretable and Predictive Connectivity-Based Neural Signature for Chronic Cannabis Use

Kulkarni, K. R., Schafer, M., Berner, L. A., Fiore, V. G., Heflin, M., Hutchison, K., Calhoun, V., Filbey, F., Pandey, G., Schiller, D. & Gu, X., 2022, (Accepted/In press) In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

A novel HDAC1/2 inhibitor alleviates physical and emotional symptoms associated with spontaneous oxycodone withdrawal in neuropathic pain mice

Pryce, K. D., Ramakrishnan, A., Kronnman, H., Nicolais, A., Polizu, C., Ruiz, A., Serafini, R., Gaspari, S., Pena, C. J., Torres-Berrio, A., Mitsi, V., Darpe, M., Shen, L. I., Nestler, E. J. & Zachariou, V., 1 May 2022, In: FASEB Journal. 36

Research output: Contribution to journal › Article › peer-review

Open Access

APOE4 confers transcriptomic and functional alterations to primary mouse microglia

Machlovi, S. I., Neuner, S. M., Hemmer, B. M., Khan, R., Liu, Y., Huang, M., Zhu, J. D., Castellano, J. M., Cai, D., Marcora, E. & Goate, A. M., Mar 2022, In: Neurobiology of Disease. 164, 105615.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

A Randomized, Triple-Blind, Comparator-Controlled Parallel Study Investigating the Pharmacokinetics of Cannabidiol and Tetrahydrocannabinol in a Novel Delivery System, Solutech, in Association with Cannabis Use History

Berl, V., Hurd, Y. L., Lipshutz, B. H., Roggen, M., Mathur, E. J. & Evans, M., 1 Dec 2022, In: Cannabis and Cannabinoid Research. 7, 6, p. 777-789 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

A sisters search for the seeds of psychosis

Malaspina, D., Nov 2022, In: Psychiatry Research. 317, 114846.

Research output: Contribution to journal › Article › peer-review

Association between follow-up blood cultures for gram-negative bacilli bacteremia and length of hospital stay and duration of antibiotic treatment: A propensity score-matched cohort study

Mitaka, H., Fujitani, S., Kuno, T., Perlman, D. C. & Mitaka, H., 2022, (Accepted/In press) In: Infection Control and Hospital Epidemiology.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Association of BDNF Val66Met with Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease

Lim, Y. Y., Maruff, P., Barthélemy, N. R., Goate, A., Hassenstab, J., Sato, C., Fagan, A. M., Benzinger, T. L. S., Xiong, C., Cruchaga, C., Levin, J., Farlow, M. R., Graff-Radford, N. R., Laske, C., Masters, C. L., Salloway, S., Schofield, P. R., Morris, J. C., Bateman, R. J. & McDade, E., Mar 2022, In: JAMA Neurology. 79, 3, p. 261-270 10 p.

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Associations of medication with subcortical morphology across the lifespan in OCD: Results from the international ENIGMA Consortium

the ENIGMA-OCD Working Group, 1 Dec 2022, In: Journal of Affective Disorders. 318, p. 204-216 13 p.

Research output: Contribution to journal › Article › peer-review

Astrocyte-secreted glypican-4 drives APOE4-dependent tau hyperphosphorylation

Saroja, S. R., Gorbachev, K., Tcw, J., Goate, A. M. & Pereira, A. C., 23 Aug 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 34, e2108870119.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology

Morris, J. C., Weiner, M., Xiong, C., Beckett, L., Coble, D., Saito, N., Aisen, P. S., Allegri, R., Benzinger, T. L. S., Berman, S. B., Cairns, N. J., Carrillo, M. C., Chui, H. C., Chhatwal, J. P., Cruchaga, C., Fagan, A. M., Farlow, M., Fox, N. C., Ghetti, B., Goate, A. M., & 27 othersGordon, B. A., Graff-Radford, N., Day, G. S., Hassenstab, J., Ikeuchi, T., Jack, C. R., Jagust, W. J., Jucker, M., Levin, J., Massoumzadeh, P., Masters, C. L., Martins, R., McDade, E., Mori, H., Noble, J. M., Petersen, R. C., Ringman, J. M., Salloway, S., Saykin, A. J., Schofield, P. R., Shaw, L. M., Toga, A. W., Trojanowski, J. Q., Vöglein, J., Weninger, S., Bateman, R. J. & Buckles, V. D., 21 Oct 2022, In: Brain. 145, 10, p. 3594-3607 14 p.

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Availability of and Obstacles to Providing COVID-19 Vaccinations at Syringe Services Programs in the United States, 2021

Des Jarlais, D. C., Behrends, C. N., Corcorran, M. A., Glick, S. N., Perlman, D. C., Kapadia, S. N., Lu, X., Feelemyer, J., LaKosky, P., Prohaska, S. M. & Schackman, B. R., Nov 2022, In: Public Health Reports. 137, 6, p. 1066-1069 4 p.

Research output: Contribution to journal › Article › peer-review

Barriers to engaging people who use drugs in harm reduction services during the COVID-19 pandemic: A mixed methods study of syringe services program perspectives

Austin, E. J., Corcorran, M. A., Briggs, E. S., Frost, M. C., Behrends, C. N., Juarez, A. M., Frank, N. D., Healy, E., Prohaska, S. M., LaKosky, P. A., Kapadia, S. N., Perlman, D. C., Schackman, B. R., Jarlais, D. C. D., Williams, E. C. & Glick, S. N., Nov 2022, In: International Journal of Drug Policy. 109, 103825.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Baseline- and treatment-associated pain in the X:BOT comparative effectiveness study of extended-release naltrexone versus buprenorphine-naloxone for OUD

Wang, A. L., Shulman, M., Choo, T. H., Pavlicova, M., Langleben, D. D., Nunes, E. V. & Rotrosen, J., Mar 2022, In: Addiction Biology. 27, 2, e13112.

Research output: Contribution to journal › Article › peer-review

Blood miR-144-3p: a novel diagnostic and therapeutic tool for depression

van der Zee, Y. Y., Eijssen, L. M. T., Mews, P., Ramakrishnan, A., Alvarez, K., Lardner, C. K., Cates, H. M., Walker, D. M., Torres-Berrío, A., Browne, C. J., Cunningham, A., Cathomas, F., Kronman, H., Parise, E. M., de Nijs, L., Shen, L., Murrough, J. W., Rutten, B. P. F., Nestler, E. J. & Issler, O., Nov 2022, In: Molecular Psychiatry. 27, 11, p. 4536-4549 14 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Brain motor and fear circuits regulate leukocytes during acute stress

Poller, W. C., Downey, J., Mooslechner, A. A., Khan, N., Li, L., Chan, C. T., McAlpine, C. S., Xu, C., Kahles, F., He, S., Janssen, H., Mindur, J. E., Singh, S., Kiss, M. G., Alonso-Herranz, L., Iwamoto, Y., Kohler, R. H., Wong, L. P., Chetal, K., Russo, S. J., & 6 othersSadreyev, R. I., Weissleder, R., Nahrendorf, M., Frenette, P. S., Divangahi, M. & Swirski, F. K., 21 Jul 2022, In: Nature. 607, 7919, p. 578-584 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Brain structural covariation linked to screen media activity and externalizing behaviors in children

Zhao, Y., Paulus, M., Bagot, K. S., Todd Constable, R., Klar Yaggi, H., Redeker, N. S. & Potenza, M. N., 30 Jun 2022, In: Journal of Behavioral Addictions. 11, 2, p. 417-426 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

TCW, J., Qian, L., Pipalia, N. H., Chao, M. J., Liang, S. A., Shi, Y., Jain, B. R., Bertelsen, S. E., Kapoor, M., Marcora, E., Sikora, E., Andrews, E. J., Martini, A. C., Karch, C. M., Head, E., Holtzman, D. M., Zhang, B., Wang, M., Maxfield, F. R., Poon, W. W., & 1 othersGoate, A. M., 23 Jun 2022, In: Cell. 185, 13, p. 2213-2233.e25

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia

Farrelly, L. A., Zheng, S., Schrode, N., Topol, A., Bhanu, N. V., Bastle, R. M., Ramakrishnan, A., Chan, J. C., Cetin, B., Flaherty, E., Shen, L., Gleason, K., Tamminga, C. A., Garcia, B. A., Li, H., Brennand, K. J. & Maze, I., Dec 2022, In: Nature Communications. 13, 1, 2195.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Chronic Intermittent Hypoxia Enhances Pathological Tau Seeding, Propagation, and Accumulation and Exacerbates Alzheimer-like Memory and Synaptic Plasticity Deficits and Molecular Signatures

Kazim, S. F., Sharma, A., Saroja, S. R., Seo, J. H., Larson, C. S., Ramakrishnan, A., Wang, M., Blitzer, R. D., Shen, L., Peña, C. J., Crary, J. F., Shimoda, L. A., Zhang, B., Nestler, E. J. & Pereira, A. C., 15 Feb 2022, In: Biological Psychiatry. 91, 4, p. 346-358 13 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Circadian Effects on Attention and Working Memory in College Students With Attention Deficit and Hyperactivity Symptoms

Gabay, L., Miller, P., Alia-Klein, N. & Lewin, M. P., 16 May 2022, In: Frontiers in Psychology. 13, 851502.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease

Dominantly Inherited Alzheimer Network, Dec 2022, In: Acta neuropathologica communications. 10, 1, 29.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Addiction Institute of Mount Sinai

Research output

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